Thermotoga maritima MSB8: THEMA_03540
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Entry
THEMA_03540 CDS
T02976
Name
(GenBank) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--LD-lysine ligase
KO
K01928
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [EC:
6.3.2.13
]
Organism
tmi
Thermotoga maritima MSB8
Pathway
tmi00300
Lysine biosynthesis
tmi00550
Peptidoglycan biosynthesis
tmi01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
tmi00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
THEMA_03540
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
THEMA_03540
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
tmi01011
]
THEMA_03540
Enzymes [BR:
tmi01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.13 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---2,6-diaminopimelate ligase
THEMA_03540
Peptidoglycan biosynthesis and degradation proteins [BR:
tmi01011
]
Precursor biosynthesis
Amino acid ligase
THEMA_03540
BRITE hierarchy
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Med2
Motif
Other DBs
NCBI-ProteinID:
AHD17999
UniProt:
Q9WY79
Structure
PDB
PDBj
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All DBs
Position
692248..693720
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AA seq
490 aa
AA seq
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MNISTIVSNLKDLILEVRAPYDLEITGVSNHSSKVKKGDLFICRRGEKFDSHEIIPEVME
KGAVAVVVEREIDLDFPYIQVFDSRYFEAKVASLFFEDPWKDVLTFGVTGTNGKTTTTMM
IYHMLTSLGERGSVLTTAVKRILGNSYYDDITTPDAITILSAMKENREGGGKFFALEVSS
HALVQQRVEGVRFDVGIFTNISRDHLDFHGTFENYLKAKLHLFDLLKDDGVAVLNESLAD
AFNRKSRKITFGTSKNADYRLGNIEVSWEGTQFVLETPDGLLKVFTRAIGDFNAYNAAAA
IAALHQLGYDPKDLASSLETFTGVEGRFEVVRGAKKIGLNVVVDFAHSPDALEKLLKNVR
KISQGRVIVVFGAGGNSDRGKRPMMSEVASKLADVVILTTDDPRGEDPEQIMEDLIKGID
KRKPYLVLFDRREAIETALTIANRGDSVVIAGRGHERYQIIDEEKKVPFQDREVVEEIIR
DKLKGRKYAQ
NT seq
1473 nt
NT seq
+upstream
nt +downstream
nt
atgaatatatcaactatcgtgtcgaatttaaaggatctcattttggaagttcgtgcaccc
tatgatctcgaaataacaggtgtgtccaaccactcttctaaggtaaaaaaaggagatctt
ttcatctgcagaagaggggagaagttcgattcccacgagataatacccgaagtgatggaa
aaaggagcagtggctgttgtcgttgaaagggaaatagatctggattttccctacattcag
gtttttgactcgcgctattttgaggcgaaagtggccagccttttcttcgaagatccctgg
aaagacgttttaacctttggagtcacaggaacaaatggcaaaaccacaacaaccatgatg
atctaccacatgctcacctctcttggagaaagaggaagcgttctcaccaccgctgtgaag
agaatccttggaaactcctactacgacgacatcaccacaccggatgcgatcaccatcctt
tccgccatgaaagaaaacagggaaggtggagggaagttcttcgccctcgaagtctcttcc
cacgcactggtccaacaaagggtcgaaggagtcagattcgatgtaggaatattcaccaac
atatcacgcgatcacctcgattttcacggcacattcgaaaactatctgaaagcaaagctt
cacctcttcgatctgctgaaagatgatggggtcgctgttctgaacgaatcactggcggac
gctttcaatcggaagtcgcgaaaaatcacctttggaacatcgaaaaacgccgattacagg
ctgggaaacatagaagtgagctgggaaggaacacagttcgttctggaaactcccgatggt
ttgctgaaggttttcacaagagcgataggagatttcaacgcctacaacgccgcggccgct
atcgcggctcttcaccagctcggatacgatccaaaagatctggcgagttcccttgagacg
ttcacaggggtcgagggaagattcgaagtagtacggggagcaaagaagatcgggctcaac
gtcgtcgtcgatttcgctcattctccagatgcactggaaaaattactgaaaaatgtcagg
aagatctctcagggaagagtgatagttgtcttcggggccgggggaaacagcgacagggga
aaacgtcccatgatgtccgaagttgcatcaaaactcgctgacgtcgtaatcctcacaacc
gatgatccacgaggggaagacccggaacagataatggaagacctgataaagggtatagat
aaacgcaaaccgtatctggtgctcttcgacagaagagaagccatcgaaacggctctaacc
atcgccaacagaggagattctgttgtcatagcggggagaggccatgaaagataccagata
atcgatgaagaaaagaaggtgccgttccaagacagagaagtcgtggaagagatcataaga
gacaagctgaaggggaggaaatacgcccaatga
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