Trichechus manatus latirostris (Florida manatee): 101345051
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Entry
101345051 CDS
T05135
Name
(RefSeq) insulin receptor substrate 2
KO
K07187
insulin receptor substrate 2
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu04022
cGMP-PKG signaling pathway
tmu04068
FoxO signaling pathway
tmu04081
Hormone signaling
tmu04140
Autophagy - animal
tmu04152
AMPK signaling pathway
tmu04211
Longevity regulating pathway
tmu04213
Longevity regulating pathway - multiple species
tmu04910
Insulin signaling pathway
tmu04920
Adipocytokine signaling pathway
tmu04923
Regulation of lipolysis in adipocytes
tmu04930
Type II diabetes mellitus
tmu04931
Insulin resistance
tmu04932
Non-alcoholic fatty liver disease
tmu04935
Growth hormone synthesis, secretion and action
tmu05010
Alzheimer disease
tmu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
101345051
04022 cGMP-PKG signaling pathway
101345051
04152 AMPK signaling pathway
101345051
09133 Signaling molecules and interaction
04081 Hormone signaling
101345051
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101345051
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101345051
04923 Regulation of lipolysis in adipocytes
101345051
04920 Adipocytokine signaling pathway
101345051
04935 Growth hormone synthesis, secretion and action
101345051
09149 Aging
04211 Longevity regulating pathway
101345051
04213 Longevity regulating pathway - multiple species
101345051
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101345051
09164 Neurodegenerative disease
05010 Alzheimer disease
101345051
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
101345051
04932 Non-alcoholic fatty liver disease
101345051
04931 Insulin resistance
101345051
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
MEKK4_N
Motif
Other DBs
NCBI-GeneID:
101345051
NCBI-ProteinID:
XP_012412892
UniProt:
A0A2Y9G2Q0
LinkDB
All DBs
Position
Unknown
AA seq
1311 aa
AA seq
DB search
MTPQKEPRRRSVQESAPAPRKAPPRAGGKAGEGGLGSWRAMQRSKARAGPGFPGSSRSSD
PRPRPSPHPAPGFPSTKGRGAAADPALAGQLIWMLVNKRQRALRTATPVLAASCSASLPG
SGAFGGSAGAADDNYGLVAPATSVYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFV
KLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILE
AMKALKELFEFRPRSKSQSSGSSSTHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAA
TPPAAASANAAAGAKCNSCRVRTASEGDGSAGAAGAGGCRPVSVAGSPMSPGPVRTPLSR
SHTLSSGCGGHPSKVMLAPAGGALQHSRSMSMPVSHSPPAATSPGSLSSSSGHGSGSYSL
PPGPHPHLPPPLHHHQGQRPSSGSASASGSPSDPGFISLDEYGSSPGDLRAFCSHRSNTP
ESIAETPPAREGSGGELYGYMTMDRPPSHCGRPYRRVSGDGAQDLDKGLRKRTYSLTTPA
RQRAVPQPSSASLDEYTLMRATFSGSSGRLCPSCPASSPKVAYHPYPEVYGDVESGPHRS
SGSNVGADDGYMPMTPGVAPLMGGGSCKIDDYMPMSPTSVSAPKQILQPRVAAAALPPTG
AGVPATTSAAGRGFSVNGGSYKTSSPAEGSPEDNRYMRMWCGSKLSMENSDSKLLSNGDY
LNMSPSDAGTSCTPPDFFSAALHSGGETLKRVPGYCYSSLPRSYKAPYTCNGDNDQYVLM
SSPVGRILEEDRQEQQTSPQPLATPVTTQSASAFGASGGSHIPPHHPAVPSPMRQSGSGR
PEGFLNQRCRAVRPTRLSLEGLQTLPSMHEYPLPPEPKSPGEYINIDFGEAGARLSPPAP
PLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGTQSG
DPVGSLDGLLSPEASSPYPPLPPRPSASPSSASSHRQQPPLPPPPGALYRLPPVTVAATS
PGPCAASSSSLETGDNGDYTEMAFGVAATPPQPIAAPPKPEGGRVTSPTAGVKRLSLMDQ
VSGVEAFLQASQAPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHN
SASVENVSLRKSGDGGSGGVGMGLGGGDEPPRSPHQAQPALPVPSLPQQPRPWTQSQPVG
LIGCPGGSVSPMRRETSAGFQNGLNYIAIDVREETGLLPPPQQPPQPPQQPGDKNSWGRN
HSLGGLINAVGGGSSSGVCGGPGAGPLPSANAYASIDFLSHHLKEATVVKE
NT seq
3936 nt
NT seq
+upstream
nt +downstream
nt
atgacgccccagaaagagccgcgaagacggagtgtccaggagagcgctcccgccccgcga
aaggcgcccccgcgagccggtgggaaagcgggagagggcggactaggctcctggcgagcc
atgcagcgcagcaaagcccgcgcgggcccaggctttccggggagctcacgttcatccgat
ccccgcccgcggccctccccgcacccggcccccggctttccttccactaaagggcgcggg
gctgccgcggatcctgcgctcgccgggcagctaatctggatgctcgtaaacaagcgccag
cgggctctgcgcaccgccacccccgtgctcgccgcgtcctgcagcgcctccctgcccggc
agcggcgccttcgggggctcggccggcgccgccgacgacaactacgggctcgtcgcgccc
gccacctccgtctatcgcgaggtctggcaggtgaacctgaagcccaagggcctggggcag
agcaagaacctgacgggcgtgtaccggctgtgcctgtcggcgcgcaccatcggcttcgtg
aagctcaactgcgagcagccgtcggtcacgctgcagctgatgaacatccgccgctgcggc
cactcggacagcttcttcttcatcgaggtgggccgctcggccgtcacgggccccggcgag
ctgtggatgcaggccgacgactcggtggtggcgcagaacatccacgagaccatcctggag
gccatgaaggcgctcaaggagctcttcgagttccggccgcgcagcaagagccagtcgtcg
ggctcatcctccacgcaccccatcagcgtgcccggcgcgcggcgccaccaccacctggtc
aacctgccccccagccagacgggcctggtgcgccgctcgcgcaccgacagcctggccgcc
acgccgccggccgcggccagcgccaacgctgcggcgggcgccaagtgcaactcctgccgg
gtgcgcacggccagcgagggggacggcagcgcgggcgcggcgggggcagggggctgcagg
cccgtgtcggtggctgggagccccatgagtccgggaccggtgaggacgcctctgagccgc
tcgcacaccctgagcagcggctgcggcggccatccgagcaaggtgatgctggcgccggca
gggggcgccctgcaacacagccgctccatgtccatgcccgtgtcccactctcctccggcc
gccaccagccctggcagtctctcgtccagcagtgggcacggctcgggctcgtactcgctg
cctccaggcccgcacccgcacctaccgccccctctgcaccatcaccagggccagcggccc
tccagtggcagtgcctctgcctcgggctcccccagcgatcccggtttcatatcgctggat
gagtacggctctagtcctggcgacttgcgagccttttgcagccacagaagcaacactcca
gagtccatcgcagagactcctcctgccagagagggcagcgggggtgagctgtatgggtat
atgaccatggacaggcccccgagccactgtggccgcccctaccgcagagtctcaggggac
ggcgctcaggacttggacaaagggctgaggaagaggacttactccctgaccacacctgcc
cgtcagcgggcagtgccccagccctcgtccgcgtcgctggatgagtacactctgatgcgg
gccaccttttccggcagctcgggccgtctctgcccctcgtgccccgcctcctcccccaaa
gtggcctaccatccctaccccgaggtctatggagacgtagagagcggtccccacagaagc
tctggcagcaatgtgggggcagacgatggctacatgcccatgaccccgggtgtggctccc
ctgatgggtggtggcagctgtaagattgatgattacatgcccatgagccccaccagcgtg
tctgctcccaagcagatcctgcagccccgagttgccgctgcagccttgcctcccaccgga
gctggggtgccagcaacaacctctgcagctggaagaggcttctcggtcaacgggggcagc
tacaagaccagctcccccgcagagggctccccagaggacaacaggtacatgcgcatgtgg
tgtggttccaagctgtccatggagaattctgacagcaagctgctttccaacggggactac
ctcaacatgtcccccagtgacgcgggcacctcctgtaccccacctgacttcttctcagct
gccttgcacagtggtggagaaacgctcaagagagtccctggttactgctacagctctcta
ccccgctcttacaaggctccttatacttgcaacggggacaacgaccagtatgtcctcatg
agctccccagtggggcggattctggaagaggacagacaagaacaacagaccagtccgcag
ccgctggccaccccagtgaccacccagtcggccagcgccttcggggccagcgggggcagc
cacatcccacctcaccacccagcagtgccttcccccatgcgacagagcggcagcggccgc
ccagagggtttcctgaaccagcgctgccgggcggtgcggcccactcgcctgtccctggag
gggcttcagactctgcccagcatgcacgagtaccctttgcccccggagcccaagagcccg
ggcgagtacatcaacattgactttggcgaggcgggagcccgcctttccccacctgcccct
ccgctgctggcctcggcggcctcgtcttcctcgctgctgtcagccagcagcccagcctcc
tcgctgggctccggcacccccgggacgagcagcgacagccggcaacgctcccctctctcc
gactacatgaacctcgacttcagctcgcccaagtcacccaaaccggggactcagagcggg
gacccagtgggctcgttggacggcctcctctcgcccgaggcttcctcgccctacccgccc
ctgccgcctcgcccctccgcctcgccctcctctgcctcctcccaccgacagcagccaccc
ctgccgccgccaccgggggcgctgtaccgcctgcctccggtgacggtggccgccacatcc
ccgggcccctgcgccgcctcttcgtcgtccttggagactggggacaacggtgactacacc
gagatggcctttggggtggctgccaccccgccacagcccatcgcggcacccccgaagccg
gagggtggccgtgtgaccagcccgacggcgggcgtgaagcggctgagcctcatggatcag
gtgtcgggcgtcgaagccttcctgcaggcgagccaagcgccagacccgcaccggggtgcc
aaggtcatccgcgccgacccgcaggggggccgccgccggcacagctcggagaccttctcc
tcgaccaccactgtgacccctgtgtccccgtccttcgcccataaccctaagcgccacaat
tcggcctccgtggaaaacgtctctctcaggaaaagtggcgatggtggcagcgggggcgtg
ggcatgggccttggagggggagatgagccgcccagatccccccaccaggcgcagccagct
cttcccgtgccatcgcttccccagcagccaaggccgtggacgcagagtcagcccgtgggg
ttgataggctgccctgggggcagtgtctccccaatgcgtagggagacctctgctggcttc
cagaatggtctcaactacatcgccattgacgtgagggaggagactgggctgctacccccg
ccgcagcagccgccgcagccgccgcagcagccaggagacaagaactcctggggccggaac
catagcctcggtggtctcatcaacgctgtaggtggcggcagctccagtggggtctgtggg
gggccaggcgctggcccgctgccctctgccaacgcctacgccagcattgacttcttgtcc
catcacctgaaggaggctactgttgtgaaagagtga
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