Trichechus manatus latirostris (Florida manatee): 101346612
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Entry
101346612 CDS
T05135
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu01524
Platinum drug resistance
tmu04010
MAPK signaling pathway
tmu04071
Sphingolipid signaling pathway
tmu04141
Protein processing in endoplasmic reticulum
tmu04210
Apoptosis
tmu04530
Tight junction
tmu04668
TNF signaling pathway
tmu04714
Thermogenesis
tmu04722
Neurotrophin signaling pathway
tmu04932
Non-alcoholic fatty liver disease
tmu04936
Alcoholic liver disease
tmu05010
Alzheimer disease
tmu05012
Parkinson disease
tmu05014
Amyotrophic lateral sclerosis
tmu05016
Huntington disease
tmu05017
Spinocerebellar ataxia
tmu05022
Pathways of neurodegeneration - multiple diseases
tmu05208
Chemical carcinogenesis - reactive oxygen species
tmu05417
Lipid and atherosclerosis
tmu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101346612
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101346612
04668 TNF signaling pathway
101346612
04071 Sphingolipid signaling pathway
101346612
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
101346612
09144 Cellular community - eukaryotes
04530 Tight junction
101346612
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
101346612
09159 Environmental adaptation
04714 Thermogenesis
101346612
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
101346612
09164 Neurodegenerative disease
05010 Alzheimer disease
101346612
05012 Parkinson disease
101346612
05014 Amyotrophic lateral sclerosis
101346612
05016 Huntington disease
101346612
05017 Spinocerebellar ataxia
101346612
05022 Pathways of neurodegeneration - multiple diseases
101346612
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101346612
05418 Fluid shear stress and atherosclerosis
101346612
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101346612
04932 Non-alcoholic fatty liver disease
101346612
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101346612
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tmu01001
]
101346612
Enzymes [BR:
tmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
101346612
Protein kinases [BR:
tmu01001
]
Serine/threonine kinases: STE group
STE11 family
101346612
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
101346612
NCBI-ProteinID:
XP_004368947
UniProt:
A0A2Y9D6X7
LinkDB
All DBs
Position
Unknown
AA seq
1374 aa
AA seq
DB search
MGTEAGEGITFSVPRFGSLGLCTFAEGGSCRRGGAAATVEGEENQQPPPPPGSFWNVESA
AGPGTGCPAASSGGSATRSRGNSGGGGGRQTTVAYVINEASQGQLVVAESEALQSLREAC
EAVGAALETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANN
IILYCDTNSDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQP
NFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIR
QRIDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALN
RRNLPGDRAKALDIMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDLGASWFK
KAFESEPTLQSGINYAVLLLATGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGF
FLGASVLANDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFAKLTTEQPVVKQELVD
FWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIH
EWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRS
AEEGDCESDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQ
PLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTI
GFYTKQILEGLRYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFT
GTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVH
PEIPESMSAEAKAFILKCFEPDPDKRACANDLLMNEFLKVSSKKKKTQPKLSALSAGSNE
YLRSISLPVPVLVEDTSSSSEYGSVSPDNELKVDPFSFKTRPKSCGEKDVKGIRTLFLGI
PDENFEDHSAPPSPEEKDSGFFLLRKDSERRATLHRILTEDQDKIVRNLMESLAQGAEEP
KLKWEHITTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNK
VLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDVEDDHEE
QPSNQTVRRPHAVIEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELV
RKEKELQALLHQAIEEKDQEIKHLKLKSQPIDIPGLPVCHLNSPGINTEDPELTDWLREN
GADEDTISRFLAEDYTLVDVLYYVTRDDLKCLRLRGGMLCTLWKAIADFRDKQP
NT seq
4125 nt
NT seq
+upstream
nt +downstream
nt
atgggcacggaggcgggcgagggcatcactttctccgtgccacgtttcggctctttgggc
ttatgcaccttcgccgagggcggcagctgccggaggggaggagcggcggcgacggtggag
ggcgaggagaaccagcagccaccgccgccacccggtagtttctggaacgtggagagcgcc
gccggccctggcaccggctgtcccgctgccagctccgggggcagcgccactcggagccgg
ggcaactctggtggcggaggcggccgacagaccactgtggcatatgtgattaacgaagcg
agccaggggcagctggtggtggccgagagtgaggccctgcagagcctgcgggaggcgtgc
gaggctgtgggcgccgcgctggagaccctgcattttggtaaactggactttggggaaacc
acggtgctggaccgcttttacaatgcagatatcgctgtggtggagatgagtgatgccttc
cggcagccatccttgttttaccaccttggggtgagagaaagtttcagcatggccaacaac
atcatcctctactgtgatactaactcagactctctgcagtcactgaaggaaatcatttgc
cagaagaataccatgtgcactgggaactacacgtttgttccttacatgataactccacat
aacaaggtctactgctgtgacagcagcttcatgaaggggttgacagagctaatgcaaccg
aacttcgagctgcttcttggacccatctgcttacctcttgtggatcgttttattcagctt
ttgaaggtggcacaagcaagttctagccagtatttccgggaatctatactcaatgatatt
aggaaagctcgtaacttgtacactggtaaagaattggcagctgaattggcaagaatccgg
cagcgaatagacaatatcgaagtcttgacagcagatattgtgataaatctcttactttct
tacagagacattcaggattatgactctattgtgaagctggtagagacattagaaaaactg
ccaacctttgatttggcctcccatcaccatgtgaagtttcattatgcgtttgcactgaat
aggagaaatctccctggagatagagcaaaagctcttgatattatgattcccctggtgcaa
agtgaaggacaagttgcttcagatatgtattgcctagtgggtcgaatctacaaagatatg
tttttggactctaatttcacagacactgaaagtagagaccttggagcctcttggttcaaa
aaggcatttgaatctgagccaacactacagtcaggaattaattatgcggtccttctcctg
gcaactgggcaccagtttgaatcttcctttgagctccggaaagttggcgtgaagctaagt
agccttcttggtaaaaagggaaacttggaaaaactccagagctactgggaagttggattt
tttctgggggccagtgtcctggccaatgaccacttgagagtcattcaagcatctgaaaag
ctttttaaactgaagacaccagcatggtacctcaagtctattgtagagacaattttgata
tataagcattttgcaaaactgaccacagaacagcctgtggtgaagcaggaacttgtggac
ttctggatggatttcctggtcgaggccacaaagacagatgttactgtagttaggtttcct
gtattaatattagaaccaaccaagatctaccaaccttcttatttgtctatcaacaatgaa
gtcgaggaaaagacaatatctatttggcatgtgcttcctgatgacaagaaaggtatacat
gagtggaatttcagtgcctcttctgtcaggggagtgagtatttctaaatttgaagaacga
tgctgttttctttatgtgcttcataattctgatgatttccaaatctacttctgtacagaa
cttcactgtaaaaagttttttgaaatggtgaataccattactgaagagaaggggagaagc
gccgaggaaggggattgtgaaagtgactccctggagtatgactatgaatatgatgaaaac
ggtgacagagtcgttttaggaaaaggcacttacggcatagtctatgcaggtcgagacttg
agcaaccaagtcagaattgctattaaggaaatcccagagagagatagcagatactcgcag
cccctacatgaagaaatagcattgcataagcatctgaaacacaaaaatattgtccagtat
ctgggctcttttagtgagaatggcttcattaaaatcttcatggagcaggtcccaggagga
agtctttctgctctccttcgttccaaatggggcccattaaaagacaatgagcaaacaatt
ggcttttatacaaagcaaatacttgaaggattaagatacctccacgacaatcagatagtt
caccgggatataaagggtgacaatgtgttgattaatacctatagtggtgttctcaagatc
tccgacttcgggacatcaaagaggttggctggcataaatccatgtactgaaactttcact
ggtacccttcagtacatggcaccagaaataatagataaagggcccagaggctacggaaaa
gcagcagacatctggtctttgggctgcaccatcattgaaatggccacaggaaaaccaccc
ttttatgaactaggagaaccacaagcagctatgttcaaggtgggaatgtttaaagtccac
ccggagattcctgagtccatgtcagcagaggccaaggcattcatattgaaatgttttgaa
ccagatccagacaagagagcatgtgctaatgacttgctgatgaatgagttcttaaaagtg
tcaagcaaaaagaaaaagacacaacctaagctttcagccctttcagctggatcaaatgaa
tatcttaggagtatatccctaccggtccctgtcctggtcgaagatacgagcagcagtagt
gaatatggctcagtttcacctgacaatgagttaaaagtggaccccttctctttcaaaaca
agacccaaatcctgtggagaaaaagatgtaaaaggaatacggacactctttttgggcatt
ccagatgaaaattttgaagatcacagtgctccaccttcccctgaagaaaaagattccggt
ttctttctgttgaggaaggacagtgaaagaagagctactcttcacaggatcctaacagaa
gaccaagacaaaatcgtgagaaatttaatggagtctttggctcagggggctgaagaacct
aaactaaagtgggaacacatcacaaccctcatcgcaagcctcagagaatttgtgagatcc
actgaccgaaaaatcatagccaccactctgtcaaagctgaagctagagctagacttcgac
agccacggcatcagtcaagttcaagtggttctctttggttttcaagatgctgtcaataag
gttcttcggaatcataacatcaagccacactggatgtttgccttggacagtatcatccgg
aaggcggtgcagacagccattaccatcctggttccagaactgaggccacattttagcctt
gcatctgagagtgataccgctgatcaagaagacttggatgtagaagatgaccatgaggaa
cagccttcaaatcaaactgttcgaagacctcatgccgtcattgaagatgctgtggctacc
tcgggggtgagcacgctcagttctactgtgtcccacgattcccagagtgctcaccggtca
ctgaatgtacagcttggaaggatgaaaatagaaactaatagattactggaagaattggtt
cggaaagagaaagaattacaagcactccttcatcaagctattgaagagaaagaccaagaa
attaaacacctgaagttgaagtcccaaccaatagatattcctggattacctgtgtgtcac
ctaaattctcctggcataaatactgaagatcctgaacttactgactggctgagagaaaat
ggagctgacgaagacactataagccggtttctggctgaggattatacactagtggatgtt
ctctactatgttacacgtgatgatttaaaatgcctgagactaagaggcgggatgctatgc
acactgtggaaggccatcgctgactttcgagacaaacagccttga
DBGET
integrated database retrieval system
