Trichechus manatus latirostris (Florida manatee): 101350401
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Entry
101350401 CDS
T05135
Name
(RefSeq) insulin receptor substrate 4 isoform X1
KO
K17446
insulin receptor substrate 4
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu04022
cGMP-PKG signaling pathway
tmu04068
FoxO signaling pathway
tmu04081
Hormone signaling
tmu04140
Autophagy - animal
tmu04152
AMPK signaling pathway
tmu04211
Longevity regulating pathway
tmu04213
Longevity regulating pathway - multiple species
tmu04910
Insulin signaling pathway
tmu04920
Adipocytokine signaling pathway
tmu04923
Regulation of lipolysis in adipocytes
tmu04930
Type II diabetes mellitus
tmu04935
Growth hormone synthesis, secretion and action
tmu05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
101350401
04022 cGMP-PKG signaling pathway
101350401
04152 AMPK signaling pathway
101350401
09133 Signaling molecules and interaction
04081 Hormone signaling
101350401
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101350401
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
101350401
04923 Regulation of lipolysis in adipocytes
101350401
04920 Adipocytokine signaling pathway
101350401
04935 Growth hormone synthesis, secretion and action
101350401
09149 Aging
04211 Longevity regulating pathway
101350401
04213 Longevity regulating pathway - multiple species
101350401
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101350401
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
101350401
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Motif
Pfam:
IRS
PH_11
PH_8
PH
Motif
Other DBs
NCBI-GeneID:
101350401
NCBI-ProteinID:
XP_004379819
UniProt:
A0A2Y9DRQ4
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Position
Unknown
AA seq
1267 aa
AA seq
DB search
MASCSFARDEVTSSLRAAAAAAAAASPAAATTPLLSSGTPTALIGTGSSCPGAMWLSAAT
GSRSDSESEEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH
SVRAAAAAAAAAASGAAMPALIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV
AENESEQESWYLLLSRLILESKRRRCGTPGVQPDQEGAALVAAAAAAEPPFYKDVWQVVI
KPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRS
TVIGPGELWMQVDDCVVAQNMHELFLEKMRALCADDYRARCRSYSISIGTHLLTLLSARR
HLDSLPFQPGGWLRRSRFEFCHLRAIGDGEDEMLLTRRFVSASEPVPHSRRGRQHLPRMH
RSRRAMSVPASCFRHLAPNPMLAPAEPPNDGACLSSEASGSGNSGEEGNPQSNESQEGNG
GDYMPMNNWGSGNGRGSGGGQGSSGQGSSSQGSGGNQCSGGGQGSGGGQSSSGGQGSGGQ
GSGGQGAGGNQCSGNGQGTAGGHGSGSGQGAGGGHGSGSGQGPGGGHGSGGGGKDSGGGK
GSGSGKGSDGNDERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPPGATGGKGKSGGR
FRLYFCADRGATKERKESKDVKEAEIPEGAARCPHRARAFDEDEDDPYVPMRPGVAAPLA
SSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDPNKEDDSKD
NDSDSDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNSFQSSPLGQSDHSEYVPML
PGKFLGRGPDKEASSSRGPKDTPSKPLVQGSCAKPGDGGSPSKPSDDGPPKNKAKRPNRL
PFVTKGNKIKPKPQKPTHQQRGAVSSRDYVNIDFTKRESNMPVPSSQRLPDSWGIIADPR
LSAFSHYVNVEFGVPFPNPANHLSNLLRAIPGANPPSLDGARWPLPPLPPSATGGNAEEE
GDYIEVIFNPAMTPAVPFADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVAR
LLQEEEQERRRPRSRSQSFFAAARAAVSAFPTDSLERELSASLASAAAAAAAPTLAVGRA
LAAASALAAAPGVGAAAASLEAAAGFDSASARWFLPVANAAAAAAAEAVRGFQNIACGSN
PEAPNPSADPARGENGVSGAAAPPPPPRRRPVPRPPEREDSDDDNTYVRMDFARPDSKKF
DSPERGW
NT seq
3804 nt
NT seq
+upstream
nt +downstream
nt
atggcgagttgctccttcgctcgcgacgaagtgacaagtagcctgagagctgcagcagcg
gcagcagcggcagcttcaccagcggcggcgaccaccccacttctttcctcgggaaccccg
accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccgcggccact
ggctcccggtcagactcggagtccgaggaggaagacctccccgtcggggacgaagtctgc
aaacgcggctacctgcggaagcagaagcatgggcacaggcgatacttcgtacttaaactc
gagaccgcggacgccccagctcggctggaatactacgaaaatgccaggaagttccggcac
agtgtccgcgccgcggcggctgcagctgcggcggccgcctcgggcgccgcgatgcccgcg
ctcatcccgccgcgacgcgtgatcaccctgtaccagtgcttctccgtgagccagcgagcc
gacgcaaggtaccgacacctcattgcccttttcacccaggacgagtactttgcaatggtg
gccgagaacgagtcggagcaggaaagctggtacttgctgctcagccgcctcatcctcgag
agcaagcgccgccgctgcggcacgcccggcgtgcagccggaccaagagggggccgcgttg
gtggcggcggcagcggcggcggagccacccttctacaaagatgtgtggcaggtagtaatc
aaaccaagggggctggggcacagaaaagagctgagcggcgtgttccggctttgcctgacc
gacgaggaggttgtgtttgtgaggctaaacaccgaagtggccagcgtggtcgtgcagctc
ctgagcattcgtcgctgcggccactcggagcagtatttctttttggaagtcggcaggtcc
accgtcatcggtccgggggagctatggatgcaggtcgatgactgtgtggtagcccaaaac
atgcacgagctgtttttggagaaaatgagagccttgtgtgcagacgactacagagcccgc
tgccgcagctacagcatcagcatcggcacccacctgttaaccctgttgtccgctaggagg
cacctggactcgctgcccttccagcctggcggctggctcagaaggtcccgctttgagttt
tgccacctgagggccattggtgacggggaagacgagatgctcctcaccaggcgtttcgta
tcagccagcgagcctgtaccccactccagacgaggaagacagcatctgcccagaatgcac
aggtccaggagagcaatgtcagtgccagccagctgttttcgccacttagcacccaacccg
atgcttgcccctgcagaaccccccaacgacggagcttgcctgtcttctgaagcatctggc
tctggtaactctggggaggaaggcaatcctcagagcaatgaaagtcaggaaggaaatgga
ggcgactacatgcccatgaacaattggggctcaggaaatggccggggctcaggaggtggc
cagggctcaagtggccagggctccagtagccagggttcaggaggaaaccagtgctccggt
gggggacagggctctggcggtggccagagctcaagtggtggccagggctcaggaggccag
ggctcaggaggccagggtgcaggaggaaaccagtgctcaggaaatggccagggcaccgca
ggtggccatggctcaggcagtggccagggggctggaggtggccatggctcaggtagtggc
caggggcctggaggtggccatggctcaggaggtggtggcaaggactctggagggggcaag
ggctcaggaagtgggaaaggctcagatggcaatgatgaacgtggaaaatctctgaagaaa
agatcctactttggcaaattaactcaaagcaagcaacagcaaatgccaccacctccacca
cccccacctccacccccaccacctggagcaactggtggaaaagggaagtctggaggcagg
ttccgactttatttttgtgctgacagaggagccacaaaagaacgaaaagaatccaaggat
gtcaaagaggcagagatccctgaaggtgcagctcggtgtccccacagagccagagctttt
gatgaagatgaagatgacccatacgtgccaatgaggccaggggttgctgcccctctcgca
agctccagcgattatatgcccatggctcctcaaaatgtctctgcctcaaaaaagcgccac
tctcgatcaccttttgaagattcaagagggtacatgatgatgtttcccagagtgagccca
ccacctgcaccaagtccccccaaagcacctgatcctaataaagaggatgactcaaaggac
aatgacagtgacagtgactacatgttcatggctcctggagctggtgcaattccaaaaaac
cccagaaatcctcagggcggctcttcgtctaaaagttggagctcctacttctctctgcca
aactcttttcagagctcccccttgggacagagtgaccacagtgagtatgtacccatgtta
cctgggaagttcctggggaggggcccagacaaagaagcctcatctagcagaggccccaaa
gatacaccttcaaagcctttagttcaggggtcgtgcgcaaagcctggagatggggggtca
ccctcaaagccctcagatgatgggcccccaaagaacaaggctaagagacccaatagactt
cctttcgttacaaaaggaaataaaatcaagccaaaaccacaaaagcccacacatcagcag
agaggagctgtcagctctcgtgactacgtcaacattgacttcactaagagagagagcaat
atgccagtcccctcttctcaaagactcccagattcgtggggcataattgctgaccctaga
ctgtcagccttttctcattatgtgaatgttgagtttggagtgccatttccaaatccagca
aaccacctctcaaatcttttaagagctattccaggtgccaatcccccatctctggacggt
gctaggtggccacttcctcctcttcctcccagtgctacgggtggcaacgccgaggaagag
ggcgactacattgaagtgattttcaacccagcaatgacaccagccgtgccttttgctgac
agtgccattcgctatgatgctgaaacaggtcgaatctatgtggtcgacccattttctgag
tgctgtatggacatttctctctcccccagccgatgctctgagccgccacctgtagctagg
ttgctgcaggaagaagagcaagagagaagacggccccgaagccgttcgcaaagtttcttt
gcagccgccagagccgctgtctctgcttttccaaccgacagcctcgagagagagctttct
gcctccttagcctcggccgccgcggcagccgctgctccaaccttagcggtgggccgggct
ttagccgcagcctccgccctggccgcggccccgggcgtcggcgcagccgccgcgagcttg
gaagcggccgctgggtttgactccgcctccgcccgctggtttctacctgttgctaatgct
gctgctgcagccgccgctgaagccgtaagggggttccaaaacattgcctgtggctcgaat
cccgaagccccaaacccatctgcagatcctgccagaggtgagaacggggtgagtggggct
gccgctcccccgccaccacctcgccgccgcccagtgccaagacccccggagcgagaagat
tctgacgacgacaacacttacgtgagaatggactttgccagacctgacagcaagaagttc
gactctcccgaaagaggttggtaa
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