Trichechus manatus latirostris (Florida manatee): 101354434
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Entry
101354434 CDS
T05135
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu01521
EGFR tyrosine kinase inhibitor resistance
tmu04010
MAPK signaling pathway
tmu04012
ErbB signaling pathway
tmu04020
Calcium signaling pathway
tmu04151
PI3K-Akt signaling pathway
tmu05205
Proteoglycans in cancer
tmu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101354434
04012 ErbB signaling pathway
101354434
04020 Calcium signaling pathway
101354434
04151 PI3K-Akt signaling pathway
101354434
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101354434
05205 Proteoglycans in cancer
101354434
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101354434
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tmu01001
]
101354434
Enzymes [BR:
tmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101354434
Protein kinases [BR:
tmu01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
101354434
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
TM_ErbB1
Kinase-like
Motif
Other DBs
NCBI-GeneID:
101354434
NCBI-ProteinID:
XP_004380000
UniProt:
A0A2Y9DRU8
LinkDB
All DBs
Position
Unknown
AA seq
1340 aa
AA seq
DB search
MRAKGALQVLSLLLSLAQGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLYKLYNRCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRFTQLTEILSGGVYIERNEKLCHMDTIDWRDIVRHQDAEIVVKENG
KSCPPCHEVCKGRCWGPGLEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD
TDCIACRHFNDSGACVRQCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQAS
CVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFQTVREITGYLNIQSWPPHMHNFSVFSNLTTIEG
RSLYNRGFSLLIMKNLNITSLGLRSLREISAGRIYISANRQLCYHHSLNWTKLLRGPAEE
RLDIKHNRPRRDCVAEGKVCDPLCSGGCWGPGPGQCLSCQNYSRGGVCVTHCNFLNGEPR
EFAHEAECFSCHPECQPMEGTATCNGSGSDACAQCAHFRDGPHCVSSCPHGVLGAKGPIY
KFPDVQNECRPCHENCTQGCKGPDLQDCLDQNQVPISKTHLAMALALVVGSLMIFLILGC
TFLYWRGRQIQNKRAMRRYLERGESIEPLDPREKANKVLARIFKETELRKLKVLGSGVFG
TVHKGVWIPEGESIKIPVCIKVIEDKSGRQNFQAVTDHMLAIGSLDHAHIVRLLGLCPGS
SLQLVTQYLPLGSLLDYVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNVL
LKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVTV
WELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKEL
ANEFTRMARDPPRYLVIKSESGPGIPPGAEPPALTNKELEEVELEPELDLDLDLEAEEDN
LATTLGSALSLPVGTLTRPRGSQSLLSPSSGYMPMNQGNLGEACQESAVGGGSERCPRPA
SLHPVPRRHLTSESSEGHVTGSEAELQENASVCRSRSRSRSPRPCGDSAYHSQRHSLLTP
VTPLSPPGLEEEDVNGYVMPDTHLKGTPSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNG
RRRCSPPRPPRPSSLEELGYEYMDVGSDLSASLGSTQSCPLHPVPIMPTAGTTPDEDYEY
MNRRHGGGDPGGDYASMGACSAAEQGYEEMRALRGPGHHAPTVHYARLKTLRSLEATDSA
FDNPDYWHSRLFPKTNAQRT
NT seq
4023 nt
NT seq
+upstream
nt +downstream
nt
atgagggcgaaaggggctctgcaggtgctgagcttgcttctcagcctggcccaaggctct
gaggtgggcaactcgcaggcagtgtgtcctggaactctgaatgggctgagtgtgactggc
gatgcagagaaccaataccagacactgtacaagctctacaataggtgcgaggtggtgatg
gggaaccttgagatcgtgctcacaggacacaatgctgacctctcgttcctgcagtggatc
cgagaagtgacgggctatgtccttgtggccatgaatgaattctccacactgcccctgccc
aacctgcgagtggtacgggggacccaggtctacgatgggaagtttgccatcttcgtcatg
ttgaactataacaccaactccagccacgctctgcgccagctccgctttactcagctcact
gaaattctgtcagggggtgtttatattgagaggaatgagaaactttgtcacatggacaca
attgactggagggacatcgtgaggcaccaggatgctgaaatagtggtgaaggaaaatggc
aagagctgtcccccctgtcatgaggtctgcaaaggacgatgctggggtccaggactggaa
gattgccagacattgaccaagaccatctgtgcccctcaatgtaacggtcactgctttgga
cctaaccccaaccagtgctgccatgatgagtgtgcagggggatgctcaggccctcaggac
acagactgcattgcctgccgacacttcaatgacagtggagcctgtgtacgtcagtgtcca
cagcctcttgtctacaacaagctaactttccagctggagcccaatccccacaccaagtat
cagtatggaggagtttgtgtggccagctgtccccataactttgtggtggatcaagcttct
tgtgtcagggcctgtcctccagacaagatggaggtagataaaaatgggctcaagatgtgt
gagccttgtggagggctgtgccccaaagcctgtgaagggacgggctctggcagccgcttc
cagactgtggactcgagcaacatcgatggatttgtgaactgcaccaagatcctaggcaac
ctggacttccttatcactggcctcaatggagacccctggcacaagatccctgccctagac
cctgagaaactcaatgtcttccagacagtacgggagatcacaggttacctaaacatccag
tcctggcctccgcacatgcacaacttcagtgtcttttccaacctgacaaccattgagggc
agaagtctttacaaccggggcttctcactgttgatcatgaagaacttgaatatcacgtct
ctgggcctccggtccctgagggaaattagtgctggacgtatctacataagtgccaatcgg
cagctctgctatcaccattctctgaactggaccaagctgcttcggggacctgcagaagag
agactagacatcaagcataatcggccccgcagagattgcgtggcagagggcaaagtgtgt
gacccactgtgctccgggggatgctggggcccaggccctggtcagtgcttatcttgccaa
aactacagccgaggaggtgtctgcgtgacccactgcaactttctgaatggggagcctcgt
gagtttgcccatgaggctgaatgtttctcctgccacccggaatgccaacccatggagggc
actgccacatgcaatggctcgggctctgatgcttgtgctcagtgtgcccattttcgagat
gggccccactgtgtgagcagctgcccccatggagtcctaggtgccaagggtcccatctac
aagttcccggatgttcagaatgaatgccgaccctgtcatgagaactgcacccaagggtgt
aaaggaccagacctgcaagattgtttagaccaaaatcaggtgccgatcagcaaaacccat
ctggcaatggctttggcattggtagtaggatcgcttatgattttcctgatcctgggctgc
acttttctctactggcgtgggcgccagatccagaataaaagggccatgaggcgctacttg
gaacggggtgagagtatagagcctctggatcccagagagaaggctaacaaggtcttggcc
agaatcttcaaagagacagagctgaggaagcttaaagtgcttgggtcaggcgtctttgga
actgtgcacaaaggtgtgtggatccctgaaggtgaatccatcaagattccagtctgcatt
aaagtcattgaggacaagagtggacggcagaattttcaagctgtgacagaccatatgctg
gccattggcagcctagaccatgcccacattgtacggctgctgggactgtgcccagggtca
tctctacagctcgtcacgcaatacttgcctctgggttccctactggattatgtgagacaa
caccggggggccctaggaccacaactgctgctcaactggggagtacaaattgccaagggt
atgtactaccttgaggagcatggtatggtgcataggaacctggccgctcgaaacgtgcta
ctcaagtcacccagtcaggttcaggtggcagattttggggtggctgacctgctgccccct
gatgataagcagctactacacagtgaggccaagactccaattaagtggatggccctcgag
agcatccactttgggaaatacacacaccagagtgacgtctggagctatggtgtgacagtt
tgggagctgatgaccttcggggcagagccctatgcagggttgcgactggctgaagtacca
gatctgctggagaagggggagcggttggcacagccccagatctgcaccattgatgtctac
atggtcatggtcaagtgttggatgattgacgagaacattcgccccacctttaaagaacta
gccaatgagttcaccaggatggctcgtgacccaccccggtatctggtcataaagagcgag
agcgggcctggaatcccccctggggcagagccccctgctctgacaaataaggaactagaa
gaagtagagctggagccagagctagacctggacctggacttggaggcagaggaggacaac
ctggcaaccacactgggctctgccctcagcctgccagttggaacacttactcggccacgt
ggaagccagagtcttctaagtccatcatctggatacatgcccatgaaccagggtaatctt
ggggaggcttgccaggaatctgcagttggtgggggtagtgaacggtgccctcgtccagcc
tccttgcacccagtgccacggcgacacctgacatcagagtcatcagagggccacgtgaca
ggctctgaggccgagctccaggagaatgcatcagtgtgtaggagccggagccggagccgg
agcccgcggccatgtggggacagcgcctaccattcccagcgccacagcctgcttactcct
gtcaccccactctccccaccagggctagaggaagaggatgtcaatggttatgtcatgcca
gatacccaccttaaaggtactccctcctcccgggaaggtactctttcttcagtgggtctc
agttctgtcctgggtacggaagaagaagatgaagatgaggagtatgaatacatgaacggg
aggagaaggtgcagtccacctcgtcctcctaggccaagttccctcgaggagctgggttat
gaatacatggatgtgggatcagacctcagtgcgtccctgggcagcacacagagttgccca
ctccaccctgtgcccatcatgcccactgctggcacaactccagatgaagactatgagtac
atgaaccgacgacacggtggaggagatcctgggggggattatgcatccatgggggcctgc
tcggcagctgagcaagggtatgaagagatgagagctttgcgggggcctggacaccatgcc
cccactgtccattatgcccgtctcaaaactctacggagcttagaagccactgactctgcc
tttgataaccctgattactggcatagcaggcttttccccaagaccaatgcccagagaaca
taa
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