Trichechus manatus latirostris (Florida manatee): 101356519
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Entry
101356519 CDS
T05135
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
tmu
Trichechus manatus latirostris (Florida manatee)
Pathway
tmu04120
Ubiquitin mediated proteolysis
tmu04144
Endocytosis
tmu04330
Notch signaling pathway
tmu04668
TNF signaling pathway
tmu04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
tmu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101356519
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
101356519
04668 TNF signaling pathway
101356519
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101356519
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101356519
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tmu04131
]
101356519
04121 Ubiquitin system [BR:
tmu04121
]
101356519
Enzymes [BR:
tmu01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
101356519
Membrane trafficking [BR:
tmu04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
101356519
Ubiquitin system [BR:
tmu04121
]
Ubiquitin ligases (E3)
HECT type E3
101356519
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
PQQ_2
Motif
Other DBs
NCBI-GeneID:
101356519
NCBI-ProteinID:
XP_004370480
UniProt:
A0A2Y9QGU3
LinkDB
All DBs
Position
Unknown
AA seq
861 aa
AA seq
DB search
MSDSGSQLGSMGSLSMKSQLQITVISAKLKEKKNWFGPSPYVEVTVDGQSKKTEKCNNTN
SPKWKQPLTVIVTPMSKLHFRVWSHQTLKSDVLLGTATLDIYEMLKSNNMKLEEVVVTLQ
LVGDKEPAEIIGDLSICLDGLQLESEVVINGETTCSESASQNDDGSRPKDETRANTNGSD
DPEDAGSGENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESDG
SSTGSLPPTNTNANTSEGATSGLIIPLTISGGAGPRPLNPVAQAPLPPGWEQRVDQHGRV
YYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQL
QRSQLQGAMQQFNQRFIYGNQDLFATSQSKEFDPLGPLPSGWEKRTDSNGRVYFVNHNTR
ITQWEDPRSQGQLNEKPLPEGWEMRFTVDGISYFVDHNRRTTTYIDPRTGKSALDNGPQI
AYVRDFKAKVQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIFL
GEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFIG
RFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGLE
MYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGFN
EILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDNE
KRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYKS
YEQLKEKLLFAIEETGGFGQE
NT seq
2586 nt
NT seq
+upstream
nt +downstream
nt
atgtctgatagtggatcacaacttggttcaatgggtagcctgagcatgaaatcacaactt
cagatcaccgtcatctcagcaaaactcaaagaaaaaaagaattggtttggaccaagtcct
tatgtggaagtcacagttgatggacagtcaaagaagacagaaaaatgcaacaatacgaac
agtcccaaatggaagcagccccttacagttatcgtcacccctatgagtaaattacatttt
cgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctacattagat
atttatgaaatgttaaaatcaaacaatatgaaacttgaagaagtggttgtgactttgcag
cttgtaggtgacaaagagccagcagagataataggagacttgtccatttgtcttgatggg
ctgcagttagagtctgaagttgttattaatggtgaaactacatgctcagaaagtgcttca
cagaatgatgatggctccaggcccaaggatgaaacaagagcaaacacaaatggatcagat
gaccctgaggatgcagggtctggtgaaaatagaagggtcaatggaaataattctccatca
ctctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctccacct
accccacgtagaccagcatctgtcaacggttcgccatctgccacttcagaaagtgacgga
tctagtacaggctctctgccaccaacaaatacaaatgcaaatacatctgaaggcgctaca
tctggattaataattcctcttactatatctggaggtgcaggccctaggcccttaaatcct
gtcgctcaagctcccctaccacctggttgggagcagagagtggaccagcatgggcgagtc
tactatgtagatcatgttgaaaaacgaacaacatgggatagaccagaacctctacctccg
ggttgggagcggcgggttgacaacatgggacgtatttattatgttgaccatttcacaaga
acaacaacatggcagaggcctacattggaatctgtccgtaactatgaacagtggcagcta
caacgaagtcaacttcaaggagcaatgcagcagtttaaccagagattcatttatgggaat
caggatttgttcgctacatcacaaagtaaagaatttgatccccttggtccattgccatct
ggatgggagaagagaacggacagcaatggcagagtatattttgtcaaccacaacactcgt
attacacagtgggaagatcccagaagtcaaggccagttaaatgaaaagcccttaccagaa
ggctgggaaatgagattcactgtggatggaatttcatattttgtggaccacaatagaaga
acaaccacctatatagatccccgcacaggaaaatctgccctagacaatggaccccagatt
gcctatgttcgggacttcaaggcaaaggttcagtatttccggttctggtgtcagcaactg
gccatgcctcagcacataaagattacagtgacaagaaaaacattgtttgaggattccttt
cagcagataatgagcttcagtcctcaagatctgcgaagacgtttgtgggtgatttttcta
ggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtcacat
gaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactattgcttg
cagataaaccctgcctcttacatcaatccagatcacctgaaatattttcgttttattggc
aggtttattgccatggctctgttccatgggaaattcatagacacgggtttttctttgcca
ttctacaagcgtatcttgaacaaaccagtcggactcaaggatttagaatctattgatcca
gaattttacaattctctcatctgggtaaaagaaaacaatattgaagaatgtggtttggaa
atgtacttctcagtcgataaggaaattcttggtgaaattaagagtcatgatttgaaaccc
aatggcggcaatattcttgtaacagaagaaaataaagaggaatacatcagaatggtagct
gagtggaggttgtctcgaggcgttgaagaacagacacaagctttctttgagggctttaat
gaaatacttccccagcagtatttgcaatactttgatgcaaaggaattagaggtcctttta
tgtggaatgcaagagattgatttaaatgactggcaaagacatgccatctaccgtcattac
actaggacaagcaagcaaatcatgtggttttggcagtttgttaaagaaattgataatgag
aagagaatgagacttctgcagtttgtaactggaacctgccgactgccagttggaggattt
gctgacctcatggggagcaatggaccacagaagttttgcattgaaaaagttgggaaagaa
aattggttacccagaagtcatacctgttttaaccgcctggacctgccaccctataagagt
tatgagcaactgaaggaaaagctgttgtttgccatcgaagaaacaggaggatttggacaa
gaatag
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