KEGG   Thermotoga maritima MSB8: THMA_0096
Entry
THMA_0096         CDS       T03902                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
tmw  Thermotoga maritima MSB8
Pathway
tmw03030  DNA replication
tmw03410  Base excision repair
tmw03420  Nucleotide excision repair
tmw03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:tmw00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    THMA_0096 (ligA)
   03410 Base excision repair
    THMA_0096 (ligA)
   03420 Nucleotide excision repair
    THMA_0096 (ligA)
   03430 Mismatch repair
    THMA_0096 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:tmw03032]
    THMA_0096 (ligA)
   03400 DNA repair and recombination proteins [BR:tmw03400]
    THMA_0096 (ligA)
Enzymes [BR:tmw01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     THMA_0096 (ligA)
DNA replication proteins [BR:tmw03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     THMA_0096 (ligA)
DNA repair and recombination proteins [BR:tmw03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     THMA_0096 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     THMA_0096 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     THMA_0096 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      THMA_0096 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 HHH_5 BRCT DNA_ligase_ZBD HHH PTCB-BRCT HHH_8 HHH_3 5_3_exonuc RNA_ligase BRCT_2 RUBY_RBDX UPF0758_N UBA_3
Other DBs
NCBI-ProteinID: AKE27907
UniProt: Q9WXV5
LinkDB
Position
complement(103127..105193)
AA seq 688 aa
MSERKIPKEVIEEVERLREEIEYHNYRYYVLNDPVITDEEYDRLMRRLIELERMYPELVT
PDSPTQRVGGKVLEGFKTVKHSVPMLSLDNTYNEEEILEFDRRVKKALQEAEVEYVAELK
IDGVSIALRYENGRFVLGATRGDGIEGEDVSENVKTVRSIPLRLRKPVTIEVRGEIYMPV
DEFKRLNDEREEEGLPPFANPRNAAAGTLRQLNTALVAARRLDSFIYYVVHPENYGLKTQ
WEALQFLKELGFKVNPHSRLCKNIQEVIDYWKEWKERKRELDYWVDGVVVKVNRFDFQRI
LGETSKAPRWAIAFKFPAEQARTRVLDVTIQVGRTGVLTPVAELEPVQLAGTIVKRASLH
NFEYIREKDIRIGDYVFVEKAGGIIPQIVKSIPELRTGNEKEIKPPDKCPVCGGKVGKLN
PDEVAIRCLNPHCPAKLKRALRTLVSREALDIEGLGEKLIDRLVDAGLIKDIADIFYLTP
FDLAQLGPGIGQRTIAKILQEIEEAKKRPLHKLITGLGIPMVGQKTAKILAEHFKSLEAI
ADASYETLKDIPGIGPEIAKSIVEYFRNPKTREIIEKLKKAGVKLEEKVVKLDILRGLTF
AVTGTLKNFTREEIIEFLEKLGAKVVNSVSRNTDYLIVGENPGSKYERAKMLKVKMMSEE
EFLEFVRKRAELKGYNFDEIMRSWKEWS
NT seq 2067 nt   +upstreamnt  +downstreamnt
atgagtgagagaaagatcccaaaggaagtaattgaagaagtggaaaggctcagagaggag
atcgagtatcacaactacagatactacgttttgaacgatccagttattacggacgaagag
tacgatagactcatgagaaggctcattgaactggaaaggatgtatccagaactggttaca
ccggattcgccaactcagagggtagggggaaaggtactcgaaggttttaaaacggtaaag
cattccgttcctatgttgagtctggataacacgtacaacgaagaagagattctcgaattc
gatcggcgtgttaaaaaagctcttcaggaggcagaagtcgagtacgttgccgagctgaag
atagacggcgtttccatagctcttagatatgagaacggaaggttcgttctgggagcgaca
cgaggagatggaatagaaggagaagacgtctccgagaatgtgaaaaccgtacgcagtatt
ccacttcgtctgagaaagcccgtcaccatagaagtgagaggggaaatatacatgcctgtg
gatgaattcaaaagattgaacgatgaaagagaagaagaaggacttcctccctttgccaac
ccaaggaatgccgctgcaggaacgcttcggcagttgaacacggctcttgttgcggcaagg
cgtctggattcgttcatttactatgtggttcatcctgaaaactacggtctgaaaacacaa
tgggaagctcttcagtttctgaaagaactcggtttcaaggtgaatccacactccagactg
tgcaaaaacattcaggaagtgatcgattactggaaggaatggaaagaaagaaaaagggag
ctggattattgggttgatggcgttgtggtgaaggtgaacagattcgatttccagagaatt
ctcggtgagacatcgaaagcaccacgatgggctatcgcgttcaagtttcctgctgagcag
gcaagaactagggtgctggatgtcaccatccaggttggaagaacaggtgttctcacaccc
gttgccgagctcgaacccgttcagctcgctggaacgatcgtgaagagagcttcactgcac
aatttcgagtacataagagaaaaagatatcagaataggagactacgtctttgtggaaaaa
gccggtggaatcattcctcagatagtcaaatcgataccagaattgagaactggcaacgaa
aaggaaataaaaccacccgataagtgccctgtctgtggtgggaaagtaggaaagttgaat
cccgacgaggttgctatcaggtgtctaaacccgcattgtcctgctaaactgaagagagct
ttgaggactctggtttccagagaggctctcgatattgaaggactcggggagaagctgata
gacagactagtcgatgctggtctcataaaggatatagcagatatcttctaccttactcct
ttcgatctcgctcagcttggaccggggatcggtcagcgaacgatagcgaagattctccaa
gagatagaagaggcgaagaagagaccgcttcacaaactgataacgggtcttggaattccc
atggtaggtcagaagacggcaaagattctcgcggagcatttcaaatccctggaagcaatt
gcagatgcttcttatgaaacactaaaggacataccgggaatcggtccagaaatcgcaaag
agcatcgttgagtacttccgaaatccaaaaacaagggaaatcattgaaaaactcaaaaaa
gccggagtgaagctcgaagagaaagttgtgaaactcgatatcctgaggggattgactttc
gccgtgacaggtaccttgaagaactttacaagggaagaaataatagagttcctcgagaag
ctgggagcaaaagtcgtcaactctgtgagcaggaacacggattatctcatagtgggtgaa
aatcccggctccaagtacgaaagagcgaagatgttgaaagtaaaaatgatgagtgaggaa
gaattcctcgagtttgtcagaaaaagagcagaattgaagggatacaacttcgacgagata
atgaggagttggaaggaatggagttga

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