KEGG   Thauera aminoaromatica: Tmz1t_0606
Entry
Tmz1t_0606        CDS       T00804                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
tmz  Thauera aminoaromatica
Pathway
tmz00270  Cysteine and methionine metabolism
tmz00450  Selenocompound metabolism
tmz00670  One carbon pool by folate
tmz01100  Metabolic pathways
tmz01110  Biosynthesis of secondary metabolites
tmz01230  Biosynthesis of amino acids
tmz04980  Cobalamin transport and metabolism
tmz04981  Folate transport and metabolism
Module
tmz_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:tmz00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Tmz1t_0606
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Tmz1t_0606
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Tmz1t_0606
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Tmz1t_0606
   04980 Cobalamin transport and metabolism
    Tmz1t_0606
Enzymes [BR:tmz01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Tmz1t_0606
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: ACK53379
UniProt: C4ZMW7
LinkDB
Position
682965..686663
AA seq 1232 aa
MQADRSIELRQLLAERILILDGAMGTMIQQEKLGEADYRGERFLDHPKDLKGNNDLLVLT
RPDVVAGIHRAYLEAGADLIETNTFNATRVSQAEYGLEALAYELNVEGARLVRRLCDEYT
AKDPARPRFCAGVLGPTSRTLSISPDVNDPGYRNISFDALADDYYASAKGLLEGGADILL
IETIFDTLNAKAAVFAIEKLFEDLGRRWPVMISGTITDASGRTLSGQTAEAFWNSLGHAQ
PISFGLNCALGADQLRQYVEELSTACDTHVSAHPNAGLPNPLSPTGYDETPEHLAGQIRE
WAQSGLVNIVGGCCGTTPAHIAAIAEAVRGLAPRAVPVLEKKLRLSGLEPFNVGGDSLFV
NVGERTNVTGSKAFARMILEGRFDDALAVARQQVENGAQVIDINMDEAMLDSVAAMERFC
KLIATEPDISRVPIMLDSSKWSVIEAGLKCIQGKGVVNSISMKEGEAEFLRQARLARRYG
AAVIVMAFDEKGQADTFRRKTEICERAYRLLVKPVAEGGAGFPAEDIIFDPNIFAIATGI
EEHDNYAVDFINAVAWIKENLPYAKTSGGVSNVSFSFRGNDPVREAIHTVFLYHAIKAGL
SMGIVNAGQLGVYDELAPELRDKVEDVVMNRKPGAGEALVEFAQTVKGQAKESAQDLAWR
EWAVEERLSHALVKGITEFVVADTEEVRAKLEAAGKPPLAVIEGPLMAGMNVVGDLFGAG
KMFLPQVVKSARVMKQAVAHLIPYIEAEKLRTGASSKGRIVVATVKGDVHDIGKNIVGVV
LGCNGYEVIDLGVMVPAAKILEAAKEHGAQAIGLSGLITPSLEEMAHVAAEMKRQGFSVP
LLIGGATTSRNHTAIKIAPHYDQPVVYVPDASRAVGVVTALLSEGRSEAFKAEVAADYEK
IRALHANKKGMQLVSLEAARANAFRVASEYQPPRPNMLGVQAIDVELGELVDYIDWGPFF
QTWDLAGRFPAILDDEVVGEAARNVFADGKAMLDKIVAEEWLQAKAVFGLFPANAVGDDI
ELYTGEDRKHLAMVWHGLRQQHERPAGKPHWCLADFVAPKDSGVPDWVGAFAVTAGLGIE
PRVAAFEAAHDDYHAIMLKSLADRLAEACAEWLHERVRRECWGYAADETLDNAALIAEQY
RGIRPAPGYPACPDHTVKGPLFELLGARERIGMELTESYAMMPAAAVSGFYFAHPESHYF
AISKIGRDQLEDWARRTGMEVDEAARWLAPLL
NT seq 3699 nt   +upstreamnt  +downstreamnt
atgcaagccgaccgcagcatcgaactccgccagcttctcgccgagcgcatcctgatcctg
gacggcgccatgggcacgatgatccagcaggagaagctgggcgaggcggactaccgcggc
gagcgcttcctcgaccaccccaaggacctcaagggcaacaacgatctgctggtgctcacg
cgtccggacgtggtcgccggtatccatcgcgcctacctcgaggctggcgccgacctcatc
gagaccaacaccttcaacgccacccgcgtgtcgcaggcggagtacggcctggaggcgctg
gcctacgagctcaacgtcgagggcgcccgcctggtgcgccggctgtgcgacgaatacacc
gcaaaggaccccgccaggccgcgcttctgcgccggcgtgctcgggccgacctcgcgcacg
ctgtcgatctcgcccgatgtgaacgatcccggctaccgcaacatcagcttcgatgcgctt
gccgacgactactacgcctcggcgaagggcctgctcgaaggcggtgccgacatcctgctg
atcgagaccatcttcgatacgctgaatgccaaggcggcggtgttcgcgatcgagaagctg
ttcgaggacctcggccggcgctggccggtgatgatctccggcaccatcaccgacgcctcg
ggccgcacgctgtcgggccagaccgcggaggccttctggaactcgctcggccacgcgcag
ccgatcagcttcggcctcaactgcgcgctcggcgccgaccagctgcgccagtacgtcgag
gaactctccaccgcctgcgacacccacgtgtccgcccaccccaacgccggcctgcccaac
ccgctgtcgcccaccggctacgacgagacgcccgagcacctcgccggccagattcgcgag
tgggcgcagagcggcctggtgaacatcgtcggcggctgctgcggcaccacgccggcgcac
atcgcggcgatcgccgaagcggtccggggcctggcgccgcgcgccgtgccggtgctggag
aaaaagctgcgcctgtccgggctggagcccttcaacgtcggcggcgacagtcttttcgtc
aacgtcggcgagcgcaccaacgtcaccggttccaaggccttcgcgcgcatgatcctcgag
ggccgcttcgacgacgcgctcgcggtggcgcgccagcaggtcgaaaacggtgcccaggtc
atcgacatcaacatggacgaggcgatgctggattcggtcgccgccatggagcgcttctgc
aagttgatcgccaccgagcccgacatctcgcgtgtgccgatcatgctcgactcgtcgaag
tggtcggtgatcgaggccggcctcaagtgcatccagggcaagggcgtggtcaactcgatc
tcgatgaaggagggcgaggcagagttcctgcgccaggcgcggctcgcacgccgctatggt
gcggcagtgatcgtgatggccttcgacgaaaagggtcaggccgacaccttccgccgcaag
accgagatctgcgagcgcgcctacaggctgctggtgaagccggtggccgagggcggcgcc
ggcttcccggccgaggacatcatcttcgaccccaacatcttcgccatcgccaccggcatc
gaggagcacgacaactacgcggtcgacttcatcaacgcggtggcctggatcaaggagaac
ctgccgtacgccaagacctcgggcggggtgtcgaacgtgtccttcagcttccgcggcaac
gacccggtgcgcgaggcgatccacaccgtgttcctctaccacgcgatcaaggccggcttg
tcgatgggcatcgtcaatgccggccagctcggcgtctatgacgagctcgcgcccgagctg
cgcgacaaggtcgaggacgtggtgatgaaccgcaagcccggggcgggcgaggcgctggtc
gagttcgcgcagacggtgaagggccaggccaaggagtccgcgcaggacctcgcctggcgc
gagtgggcggtcgaggagcgcttgagccacgcgctggtcaagggcatcaccgagttcgtc
gtcgccgataccgaggaggtgagggcgaagctggaggccgcgggcaagccgccgctggcg
gtgatcgagggcccgctgatggccggcatgaacgtggtcggcgacctcttcggcgcgggc
aagatgttcctgccccaggtggtgaagtcggcgcgcgtcatgaagcaggcggtggcgcac
ctgatcccctacatcgaggccgagaagctgcgcaccggcgccagcagcaagggccgtatc
gtcgtcgccacggtcaagggcgacgtgcacgacatcggcaagaacatcgtcggcgtggtg
ctcggctgcaatggctacgaggtgatcgacctcggcgtgatggtgccggcagcgaagatc
ctcgaggcggcgaaggagcacggcgcgcaggcgatcggcctgtccggcctgatcacgccc
tcgctcgaggagatggcccacgtcgccgccgagatgaagcgccagggcttttccgtgccg
ctgctgatcggcggcgccaccaccagccgcaaccacaccgcgatcaagatcgcgccgcac
tacgatcagccggtggtgtacgtgcccgacgcctcgcgtgcggtgggcgtggtcaccgcg
ctgctgtccgaaggccggagcgaggccttcaaggccgaggtcgccgccgactacgagaag
atccgcgcgctgcacgccaacaagaagggcatgcagttggtgagcctcgaggctgcgcgc
gccaacgccttccgcgtcgcctccgaataccagccgccgcgcccgaacatgctgggcgtg
caggcgatcgacgtcgagctcggcgagctggtcgactacatcgactggggcccgttcttc
cagacctgggacctcgccggccgcttccccgccatcctcgacgacgaagtggtgggtgag
gccgcgcgcaacgtgttcgccgacggcaaggcgatgctggacaagatcgtcgccgaggag
tggctgcaggcgaaggcggtgttcggcctgttcccggccaacgcggtgggcgacgacatc
gagctctacaccggcgaggaccgcaagcacctggccatggtgtggcacggcctgcgtcag
cagcacgagcgcccggcgggcaagccgcactggtgcctcgcggacttcgtcgcgcccaag
gactcgggcgtgcccgactgggtcggcgccttcgcggtgaccgccggcctcggcatcgag
cccagggtcgccgcgttcgaggccgcgcacgacgactaccacgcgatcatgttgaagagc
ctggccgaccgcctcgccgaggcctgcgccgagtggctgcacgagcgcgtgcgccgcgag
tgctggggctacgccgccgacgagacgctcgacaacgccgcgctgatcgccgagcagtac
cgcggcatccgcccggcgccgggctatccggcctgcccggaccacaccgtcaagggtccg
ctgttcgagctcctcggcgcgcgcgagcgcatcggcatggagctcaccgagagctacgcg
atgatgccggcggcggcggtgagcggcttctacttcgcccaccccgagagccactatttc
gcgatctcgaagatcggccgcgaccagctcgaggactgggcgcgccgtaccggcatggag
gtcgacgaagccgcgcgctggctggcgccgctgctctga

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