Thauera aminoaromatica: Tmz1t_3195
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Entry
Tmz1t_3195 CDS
T00804
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
tmz
Thauera aminoaromatica
Pathway
tmz00010
Glycolysis / Gluconeogenesis
tmz00020
Citrate cycle (TCA cycle)
tmz00620
Pyruvate metabolism
tmz00785
Lipoic acid metabolism
tmz01100
Metabolic pathways
tmz01110
Biosynthesis of secondary metabolites
tmz01120
Microbial metabolism in diverse environments
tmz01200
Carbon metabolism
tmz01210
2-Oxocarboxylic acid metabolism
Module
tmz_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tmz00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Tmz1t_3195
00020 Citrate cycle (TCA cycle)
Tmz1t_3195
00620 Pyruvate metabolism
Tmz1t_3195
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Tmz1t_3195
Enzymes [BR:
tmz01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Tmz1t_3195
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
ACR01790
UniProt:
C4KBL4
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Position
3478413..3481094
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AA seq
893 aa
AA seq
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MTGISTVLPQTDTDAQETKEWLDALAAVVEHEGPERAHYLIETLIATARQEGVNIPYSAT
TEYINTIPAERQPPYPGDPDLEIKIHSYIRWNAMAMVVRANKDTNVGGHIASFASAAALY
DVGFSHFWHAPSEAHDGDLIYFQGHSVPGVYARAFMLGRLTEEQMDSFRQEVGGKGISSY
PHPWLMPDFWQFPTVSMGLGPLCAIYSARFMKYLASRGLIDPARAQQRKVWAFLGDGETD
EVESLGAIGMAGREGLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIW
GTHWDALFARDKKGILKQRMMELCDGEYQTFKAKDGAYVREHFFNTPELRALVADWTDEQ
VWNLNRGGHDLFKIFSAYKAANEHKGQPTLILAKTIKGFGMGQAGEAMNISHQQKKMDVE
AIRRFRDRFGLPVPDDQLEALPYLKFAEDSPEHKYLLKHRMDLGGFLPQRRRKAAALEIP
GLDTFAALLKASGEGRELSTTMAVVRIMNTLLKDKQIGKHVVPIVPDESRTFGMEGMFRQ
YGIWNQQGQNYVPEDHDQLMFYKESKTGQVLQEGINEAGAMADWIAAGTAYSVHNVQMIP
FYIFYSMFGLQRTMDLCWAAADQRTRGFLIGGTAGRTTLNGEGLQHEDGHSLIMANMIPN
CISYDPTFQYEVAVIVQDGLRRMFAEQEDVYYYITVMNENYEHPEMPVGAEADILKGLYL
FRQGGQAKTPRVQLMGSGTIFREVIAAAELLKADWGVESDIWGAPSFNELARNGHDVERW
NLLHPMEEPRKTHVQQKLAGFAGPVVAATDYIRMFPEQIRAQLDRTYVTLGTDGFGRSDT
REQLRHFFEVDRHWVTLAALKALADEGTIGRDKVAAAMVKYQLDPSKPNPMSV
NT seq
2682 nt
NT seq
+upstream
nt +downstream
nt
atgaccggaatcagcaccgttctcccgcaaaccgacacggatgcgcaggaaacgaaggaa
tggctggacgcgctcgccgccgtcgtcgaacacgaaggccccgagcgcgcccactacctg
atcgagaccctgatcgccacggcgcgccaggagggggtgaacatcccctactcggccacg
accgagtacatcaacacgattccggccgagcgccagccgccctacccgggcgatccggat
ctggagatcaagatccactcctacatccgctggaacgcgatggcgatggtggtgcgggcg
aacaaggacaccaacgtgggcggtcacatcgcctccttcgcctcggcggcggcgctctac
gacgtgggcttctcgcacttctggcacgcgccctccgaggcgcacgacggcgacctgatc
tacttccagggccactcggtgccgggcgtgtatgcgcgcgcgttcatgctgggccgtctg
accgaagaacagatggacagcttccgccaggaagtgggcggcaagggcatctcgtcctac
ccgcacccctggctgatgcccgacttctggcagttccccaccgtgtcgatgggcctgggt
ccgctgtgcgcgatctactcggcgcgcttcatgaaatacctggccagccgcggcctgatc
gatccggcacgcgcgcagcagcgcaaggtgtgggccttcctgggcgacggcgagaccgac
gaggtcgaatcgctgggcgcgatcggcatggccggccgcgagggcctggacaacctcgtc
ttcgtgatcaactgcaacctgcagcgcctcgatggtccggtgcgcggcaacggcaagatc
atccaggagctcgagtccgagttccgcggcgcgggctggaacgtcatcaaggtgatctgg
ggcacgcactgggacgcgctcttcgcccgcgacaagaagggcatcctcaagcagcgcatg
atggagttgtgcgacggcgagtatcagaccttcaaggccaaggacggcgcctacgtgcgc
gagcacttcttcaacacgcccgagctgcgcgcgctggtggccgactggaccgacgagcag
gtgtggaacctgaaccgcggcggccacgatctcttcaagatcttctccgcctacaaggcc
gccaacgagcacaaggggcagcccacgctgatcctggccaagaccatcaagggcttcggc
atgggccaggccggcgaggcgatgaacatctcgcaccagcagaaaaagatggacgtcgag
gccatccgccgcttccgcgaccgcttcggcctgccggtgcccgacgaccagctcgaggca
ctgccctacctgaagttcgccgaggactctcccgagcacaagtacctgctcaagcaccgc
atggacctgggcggcttcctgccgcagcgccggcgcaaggccgccgcgctcgagatcccg
ggcctggacaccttcgccgcgctgctcaaggcctcgggcgagggccgcgagctgtcgacc
accatggcggtggtgcgcatcatgaacacgctgttgaaggacaagcagatcggcaagcat
gtcgtgccgatcgtcccggacgaaagccgcaccttcggcatggagggcatgttccgccag
tacggcatatggaaccagcaaggccagaactacgtgccggaagaccatgaccagctcatg
ttctacaaggagagcaagaccggccaggtgctgcaggaaggcatcaacgaggccggcgcg
atggccgactggatcgccgcgggcaccgcctacagcgtgcacaacgtgcagatgatcccg
ttctacatcttctattccatgttcggcctgcagcgcaccatggacctgtgctgggcggcc
gccgaccagcgcacccgcggcttcctgatcgggggcaccgccgggcgcacgaccctgaac
ggcgaaggcctgcagcacgaggacggccacagcctgatcatggccaacatgatccccaac
tgcatcagctacgacccgaccttccagtacgaggtcgcggtgatcgtgcaggacggcctg
cgccgcatgttcgccgagcaggaggacgtgtattactacatcacggtgatgaacgagaac
tacgaacatcccgagatgccggttggcgccgaggccgacatcctcaaaggcctgtacctg
ttccgccagggcggccaggccaagaccccgcgcgtgcagctgatgggttcgggcacgatc
ttccgcgaggtgatcgccgccgccgagctgctcaaggccgactggggcgtggagtcggac
atctggggcgcgcccagcttcaacgagctggcccgcaacggccacgacgtcgagcgctgg
aacctgctgcacccgatggaagagccgcgaaagacccacgtgcagcagaagctcgccggc
ttcgcaggcccggtcgtcgccgccaccgactacatccgcatgttccccgagcagatccgc
gcgcagctcgaccgcacttacgtcacgctgggcaccgacggcttcggccgctccgacacc
cgcgagcagctgcgccacttcttcgaggtggatcgccactgggtgacgctggccgcgctg
aaggcgctggccgacgagggcacgatcggccgcgacaaggtcgccgcggcgatggtcaag
taccagctcgacccgtccaaaccgaacccgatgtcggtctga
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