KEGG   Talpa occidentalis (Iberian mole): 119231485
Entry
119231485         CDS       T07495                                 
Symbol
ADCY1
Name
(RefSeq) adenylate cyclase type 1 isoform X1
  KO
K08041  adenylate cyclase 1 [EC:4.6.1.1]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod00230  Purine metabolism
tod01100  Metabolic pathways
tod01522  Endocrine resistance
tod04015  Rap1 signaling pathway
tod04020  Calcium signaling pathway
tod04022  cGMP-PKG signaling pathway
tod04024  cAMP signaling pathway
tod04062  Chemokine signaling pathway
tod04072  Phospholipase D signaling pathway
tod04081  Hormone signaling
tod04082  Neuroactive ligand signaling
tod04114  Oocyte meiosis
tod04211  Longevity regulating pathway
tod04213  Longevity regulating pathway - multiple species
tod04261  Adrenergic signaling in cardiomyocytes
tod04270  Vascular smooth muscle contraction
tod04371  Apelin signaling pathway
tod04540  Gap junction
tod04611  Platelet activation
tod04713  Circadian entrainment
tod04714  Thermogenesis
tod04720  Long-term potentiation
tod04723  Retrograde endocannabinoid signaling
tod04724  Glutamatergic synapse
tod04725  Cholinergic synapse
tod04727  GABAergic synapse
tod04750  Inflammatory mediator regulation of TRP channels
tod04911  Insulin secretion
tod04912  GnRH signaling pathway
tod04913  Ovarian steroidogenesis
tod04914  Progesterone-mediated oocyte maturation
tod04915  Estrogen signaling pathway
tod04916  Melanogenesis
tod04918  Thyroid hormone synthesis
tod04921  Oxytocin signaling pathway
tod04923  Regulation of lipolysis in adipocytes
tod04925  Aldosterone synthesis and secretion
tod04926  Relaxin signaling pathway
tod04927  Cortisol synthesis and secretion
tod04928  Parathyroid hormone synthesis, secretion and action
tod04934  Cushing syndrome
tod04935  Growth hormone synthesis, secretion and action
tod04970  Salivary secretion
tod04971  Gastric acid secretion
tod04972  Pancreatic secretion
tod04976  Bile secretion
tod05032  Morphine addiction
tod05142  Chagas disease
tod05146  Amoebiasis
tod05163  Human cytomegalovirus infection
tod05166  Human T-cell leukemia virus 1 infection
tod05200  Pathways in cancer
tod05207  Chemical carcinogenesis - receptor activation
tod05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tod00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    119231485 (ADCY1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    119231485 (ADCY1)
   04371 Apelin signaling pathway
    119231485 (ADCY1)
   04020 Calcium signaling pathway
    119231485 (ADCY1)
   04072 Phospholipase D signaling pathway
    119231485 (ADCY1)
   04024 cAMP signaling pathway
    119231485 (ADCY1)
   04022 cGMP-PKG signaling pathway
    119231485 (ADCY1)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    119231485 (ADCY1)
   04081 Hormone signaling
    119231485 (ADCY1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    119231485 (ADCY1)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    119231485 (ADCY1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    119231485 (ADCY1)
   04062 Chemokine signaling pathway
    119231485 (ADCY1)
  09152 Endocrine system
   04911 Insulin secretion
    119231485 (ADCY1)
   04923 Regulation of lipolysis in adipocytes
    119231485 (ADCY1)
   04912 GnRH signaling pathway
    119231485 (ADCY1)
   04913 Ovarian steroidogenesis
    119231485 (ADCY1)
   04915 Estrogen signaling pathway
    119231485 (ADCY1)
   04914 Progesterone-mediated oocyte maturation
    119231485 (ADCY1)
   04921 Oxytocin signaling pathway
    119231485 (ADCY1)
   04926 Relaxin signaling pathway
    119231485 (ADCY1)
   04935 Growth hormone synthesis, secretion and action
    119231485 (ADCY1)
   04918 Thyroid hormone synthesis
    119231485 (ADCY1)
   04928 Parathyroid hormone synthesis, secretion and action
    119231485 (ADCY1)
   04916 Melanogenesis
    119231485 (ADCY1)
   04925 Aldosterone synthesis and secretion
    119231485 (ADCY1)
   04927 Cortisol synthesis and secretion
    119231485 (ADCY1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    119231485 (ADCY1)
   04270 Vascular smooth muscle contraction
    119231485 (ADCY1)
  09154 Digestive system
   04970 Salivary secretion
    119231485 (ADCY1)
   04971 Gastric acid secretion
    119231485 (ADCY1)
   04972 Pancreatic secretion
    119231485 (ADCY1)
   04976 Bile secretion
    119231485 (ADCY1)
  09156 Nervous system
   04724 Glutamatergic synapse
    119231485 (ADCY1)
   04727 GABAergic synapse
    119231485 (ADCY1)
   04725 Cholinergic synapse
    119231485 (ADCY1)
   04720 Long-term potentiation
    119231485 (ADCY1)
   04723 Retrograde endocannabinoid signaling
    119231485 (ADCY1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    119231485 (ADCY1)
  09149 Aging
   04211 Longevity regulating pathway
    119231485 (ADCY1)
   04213 Longevity regulating pathway - multiple species
    119231485 (ADCY1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    119231485 (ADCY1)
   04714 Thermogenesis
    119231485 (ADCY1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119231485 (ADCY1)
   05207 Chemical carcinogenesis - receptor activation
    119231485 (ADCY1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    119231485 (ADCY1)
   05163 Human cytomegalovirus infection
    119231485 (ADCY1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    119231485 (ADCY1)
   05142 Chagas disease
    119231485 (ADCY1)
  09165 Substance dependence
   05032 Morphine addiction
    119231485 (ADCY1)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    119231485 (ADCY1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    119231485 (ADCY1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    119231485 (ADCY1)
Enzymes [BR:tod01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     119231485 (ADCY1)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom Pex24p
Other DBs
NCBI-GeneID: 119231485
NCBI-ProteinID: XP_037349121
LinkDB
Position
Unknown
AA seq 1251 aa
MAGAPRGRGGGGRGAGEPGGAERAAGSGGRQGLRACGEEFACPELEALFRGYTLRLEQAA
TLKALVVLSLLAGTLALAELLGAPGPAPGLAKGSHPVHCILFLALLVVTNVRSLQVPQLQ
QVGRLALLFSLTFALLCCPFALGGPAGTQAGAAAVPVAAEQGVWQLLLVTFVSYALLPVR
SVLAIGFGLVVAASHLLVTATLVPTKRSRHWSTLGANALLFVSVNMYGVFVRILAERSQR
KAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPDRIFHKIYIQRHD
NVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGL
TQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWS
NDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKTHNIETFFIVPSH
RRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDKRRALRT
TSEKLRNRSSFSTNVVYTTPGTRVNRYIGRLLEARQTELEMADLNFFTLKYKQAERERKY
HQLQDEYFTSAVVLALILAALFGLVYLLIIPQSLALLLLLVFCICFLVTCVLYLHITRVQ
RRALRTTSEKLRNRSSFSTNVVYTTPGTRVNRYIGRLLEARQTELEMADLNFFTLKYKQA
ERERKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSLALLLLLVFCICFLVTCVLYL
HITRVQCLPGCLTIQIRTVLCIFIVVLIYSVAQGWVVDCLPWAWSSSSNGSLASGGWDPA
LPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLCVLTTSYILVLELSGYTKALGSGTV
SGHSFEPIVAILLFSCTLALHARQVDVKLRLDYLWTAQAEEERDDMERVKLDNKRILFNL
LPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEI
IADFDELMEKDFYKDLEKIKTIGSTYMAAVGLAPTAGAKAQKCISSYLSTLADFAIEMFD
VLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQV
TEEVHRLLCQGAYHFVCRGKVSVKGKGEMLTYFLEGKTNGNSSQNRSLNSERKMCPYGRA
GLQTRLATGRPPVPPVASLPVRASLGTLQGSRLTPGPPSQHLPPGAAGKEA
NT seq 3756 nt   +upstreamnt  +downstreamnt
atggcgggggcgccgcgcggccgaggcggcggcggacgcggcgcgggcgagcccgggggc
gctgagcgggcggcagggtcgggcggccggcaggggctccgagcgtgcggcgaggagttc
gcgtgcccggagctggaggcgctgttccgcggctacacgctgcggctggagcaggcggcc
acgctgaaggcgctggtcgtgctcagtctcctggcgggcacgctggcgctcgccgagctc
ctgggcgcgcccgggcccgcgcctggcctggccaaaggctcgcaccccgtgcactgcatc
cttttcctggcgctcctcgtggtcaccaatgtccgctccttgcaggtgccccagctgcag
caggtcggccggctcgccctgcttttcagcctcaccttcgcactgctctgctgccccttc
gcgctcggtggtcccgccgggactcaggctggggctgctgcggtgcccgtggccgcggag
caaggcgtttggcagctccttttagtcaccttcgtgtcctatgctctgctgcccgtgcgc
agcgtgctggccatcggcttcggtctcgtggtggctgcctcacacttgctggtcacggcc
accctggtgcccaccaagcgttcacgtcactggagtacgcttggcgccaatgccctgctc
ttcgtcagcgtgaacatgtatggggtctttgtgaggatccttgctgagcgctcccagagg
aaggccttcttgcaggcccggaactgcattgaggaccggctgaggctagaggacgagaac
gagaagcaggagcggctgctcatgagtcttctaccccggaatgtcgccatggagatgaag
gaggacttcctgaagcccccagacaggattttccacaagatttacatccagaggcatgac
aatgtcagcatcctctttgctgacatcgtgggcttcactggcttggcgtcccagtgcacg
gcacaggagctggtgaaactcctcaacgagctcttcggcaagtttgatgaattggccacg
gagaaccactgccgtcgcatcaagatcctgggggactgctattactgcgtgtctggcctc
acccagcccaagaccgaccatgcccactgctgtgtggagatgggcctggacatgatcgac
accatcacgtccgtggccgaggccactgaggtggatctgaacatgcgcgtggggctgcac
accggcagggtcctctgcggagtcctgggcctgcgcaagtggcaatatgacgtgtggtcc
aatgatgtgactctagccaatgtcatggaagctgccggcttaccaggcaaggttcacatc
accaagacaactctggcgtgcttgaatggtgactatgaagtggaaccaggtcacgggcat
gagaggaacagttttttgaaaacacataacattgagacttttttcattgtgccatcacat
cggcggaagatctttccaggactgattctctctgacataaaaccagccaagaggatgaag
ttcaagaccgtctgctacttgctcgtgcagctcatgcactgccggaagatgttcaaggct
gagatccccttctccaatgtcatgacatgtgaggatgacaagcggagggcattgagaaca
acttcagagaaactcagaaaccgctcatctttctctacgaatgttgtctataccaccccg
ggcacacgtgttaacaggtacattggccgcctcctggaagcccgccagacagagctggag
atggctgacctgaacttcttcactctgaagtataagcaagccgagcgagagcgaaagtac
caccagcttcaggacgagtatttcaccagtgccgtcgtgcttgccctcattctggctgcc
ttatttggccttgtctaccttctcataatcccacagagtctggccctcctgcttctgttg
gtgttctgcatctgtttcctggtgacctgtgttctgtacctgcacatcacccgggtccag
cggagggcattgagaacaacttcagagaaactcagaaaccgctcatctttctctacgaat
gttgtctataccaccccgggcacacgtgttaacaggtacattggccgcctcctggaagcc
cgccagacagagctggagatggctgacctgaacttcttcactctgaagtataagcaagcc
gagcgagagcgaaagtaccaccagcttcaggacgagtatttcaccagtgccgtcgtgctt
gccctcattctggctgccttatttggccttgtctaccttctcataatcccacagagtctg
gccctcctgcttctgttggtgttctgcatctgtttcctggtgacctgtgttctgtacctg
cacatcacccgggtccagtgtttaccaggatgcctgacaatccagatccgcacagtcttg
tgcattttcatagtggtcttaatctactctgtagcccaaggttgggtggtggactgcctg
ccgtgggcctggagctctagttccaatgggtccctggcatccggtggctgggaccctgcc
ctgccctgtgagtcagcgccccatgccctgctctgtggcctcgtgggcacccttcctctg
gccatatttctgcgggtctcttccttgccaaaaatgatcctgctctgcgtgctcaccacg
tcctacatcctggtcctggagctcagcggatacacgaaggccctggggagtggcactgtc
tccgggcacagcttcgagcccattgtggccatcctgctgttctcgtgtacgctggccctg
cacgcccggcaggtggatgtcaagcttaggctggactacctctggactgctcaggcagag
gaggagcgggatgacatggagcgggtgaagctggacaacaagaggatcctgttcaacctc
ctgccagcccacgttgctcagcacttccttatgtccaatccccggaacatggacctctac
taccagtcgtactcgcaggtgggcgtcatgtttgcctccatccccaacttcaatgacttt
tacattgagctggatggcaacaacatgggagtggagtgcctgcggcttctgaacgagatt
attgccgactttgatgagctcatggaaaaagacttttacaaggatctggagaagatcaag
accatcgggagcacctacatggctgcagtggggttggctcccacggctggggccaaggct
cagaagtgtatctcctcctacctcagcacgctggcggattttgccatcgagatgtttgat
gtcctggatgagatcaactatcagtcctacaatgactttgtgctcagagtcggtatcaat
gttggccctgtggtggctggagtaataggtgctcgcagaccgcagtacgacatctgggga
aacacagtcaacgtggccagtcggatggacagcactggtgtccagggcagaatccaggtg
actgaggaagtacaccggctgctgtgccagggtgcgtaccacttcgtgtgtcgaggcaaa
gtcagcgtcaagggcaagggggagatgctgacgtacttcctggaaggcaaaaccaatgga
aacagctcccaaaacaggtccctgaactcagagcggaaaatgtgtccttacgggagagcc
ggccttcagaccagactggccaccggccgccctccagtgccccctgtggccagcctacct
gtcagagcaagtctggggactttgcaaggctcgaggctcacccctgggccccccagccag
cacctgccccctggagcagctgggaaggaggcttag

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