Talpa occidentalis (Iberian mole): 119235583
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Entry
119235583 CDS
T07495
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01522
Endocrine resistance
tod04012
ErbB signaling pathway
tod04062
Chemokine signaling pathway
tod04148
Efferocytosis
tod04151
PI3K-Akt signaling pathway
tod04360
Axon guidance
tod04370
VEGF signaling pathway
tod04510
Focal adhesion
tod04670
Leukocyte transendothelial migration
tod04810
Regulation of actin cytoskeleton
tod04935
Growth hormone synthesis, secretion and action
tod05100
Bacterial invasion of epithelial cells
tod05135
Yersinia infection
tod05146
Amoebiasis
tod05163
Human cytomegalovirus infection
tod05165
Human papillomavirus infection
tod05170
Human immunodeficiency virus 1 infection
tod05200
Pathways in cancer
tod05202
Transcriptional misregulation in cancer
tod05205
Proteoglycans in cancer
tod05208
Chemical carcinogenesis - reactive oxygen species
tod05222
Small cell lung cancer
tod05417
Lipid and atherosclerosis
tod05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
119235583 (PTK2)
04370 VEGF signaling pathway
119235583 (PTK2)
04151 PI3K-Akt signaling pathway
119235583 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
119235583 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
119235583 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
119235583 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
119235583 (PTK2)
04062 Chemokine signaling pathway
119235583 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
119235583 (PTK2)
09158 Development and regeneration
04360 Axon guidance
119235583 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
119235583 (PTK2)
05202 Transcriptional misregulation in cancer
119235583 (PTK2)
05205 Proteoglycans in cancer
119235583 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
119235583 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
119235583 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
119235583 (PTK2)
05163 Human cytomegalovirus infection
119235583 (PTK2)
05165 Human papillomavirus infection
119235583 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
119235583 (PTK2)
05100 Bacterial invasion of epithelial cells
119235583 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
119235583 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
119235583 (PTK2)
05418 Fluid shear stress and atherosclerosis
119235583 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
119235583 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119235583 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
tod01009
]
119235583 (PTK2)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
119235583 (PTK2)
Protein kinases [BR:
tod01001
]
Non-receptor tyrosine kinases
FAK family
119235583 (PTK2)
Protein phosphatases and associated proteins [BR:
tod01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
119235583 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
119235583
NCBI-ProteinID:
XP_037354961
LinkDB
All DBs
Position
Unknown
AA seq
1038 aa
AA seq
DB search
MAAAHLDPNLNHTPNSSPKTHLGPGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGD
ATDVRGIIQKIVDSHKVKHVACYGFRLSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEW
KYELRIRYLPKGFLNQFTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSY
WEMRGNALEKKSNYEVLEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESI
LKFFEILSPVYRFDKECFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQ
TIQYSNSEDKDRKGMLQLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFII
RPQKEGERALPSIPKLASSEKQGVRTHAVSVSETDDYAEIIDEEDTYTMPSKSYGIDEAR
DYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEAL
TMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTA
LAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPES
INFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYS
LMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMESRRQVPVSWDSGGADEAPP
KPSRPGYPSPRSSEGFYPSPQHMVQANHYQVSGYPGSHGVTAMAGSVYPGQASLLDQTDT
WNHRPQEVAMWQPGVEDAAALDLRGVGQALPSHLMEERLIRQQQEMEEDQRWLEKEERFL
TGNQHIYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLGSPGDSYNEGVKLQPQEISPPPT
ANLDRSNDRVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETVPA
LPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNL
LDVIDQARLKMLGQTRPH
NT seq
3117 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcgcacctcgacccaaacttgaaccatacaccgaactccagccccaagacg
cacctgggtcccggcgtggagcgctcccccggggcgatggagcgcgtgttgaaggtcttt
cattacttcgagaacagtagtgagccagccacctgggccagtattatccggcatggagac
gccaccgacgtcaggggcatcatccagaagatagtggacagccacaaggtgaagcacgtg
gcctgctacgggttccgcctcagtcacctgcggtccgaggaggtgcactggctccatctg
gacatgggcgtctctaacgtgagggagaagtatgaactcgcacaccccccagaggagtgg
aagtatgaattaagaattcgttatttgccaaaaggatttctaaaccagttcactgaggac
aagccaactctgaatttcttctaccagcaggtgaagagcgattacatgttggagatcgcc
gaccaggtggaccaggagatcgctttgaagttggggtgtctagaaattcggcggtcctac
tgggagatgcggggcaacgcgctggagaagaagtccaactacgaggtgctagaaaaagat
gttggtctgaagcgattttttcctagaagtttactggattctgtcaaggccaaaacacta
agaaaactgatccaacaaacttttagacagtttgccaaccttaacagagaagaaagtatt
ctgaagttcttcgagatcctctccccggtgtacagattcgataaggagtgcttcaagtgt
gcgctgggctcaagctggatcatctcagtggagctcgccattggcccagaagaaggcatc
agctacctcacggataagggctgcaatcccacacatctggccgacttcaatcaggtgcag
accattcagtattccaacagcgaagacaaggacagaaaaggaatgctgcagctgaagatc
gcgggcgcccctgagccgctgaccgtgacggcaccgtcgctgaccatcgcggagaacatg
gccgatctgatcgacgggtactgccggctggtgaatggagccacacagtccttcatcatc
aggccccagaaagaaggtgaacgggctttgccatcaataccaaagctggccagcagcgag
aagcagggcgtgcggacccatgccgtctccgtgtcagaaaccgacgattacgccgagatc
atagacgaagaagatacgtacaccatgccctcgaaaagctatggaatagatgaagccagg
gattatgagatccaaagagagagaatagaactcggacggtgtatcggcgaaggccaattt
ggagatgtgcaccaaggcgtgtacatgagcccagagaatccagctctggcggttgcaatt
aaaacatgtaaaaactgtacttcggacagtgtgagagaaaagttccttcaagaagcctta
accatgcgccagtttgaccacccacacatcgtgaagctgatcggtgtcatcacagagaac
cccgtctggataatcatggagctttgcacgcttggagagctgagatcatttttgcaagtg
aggaaatacagtttggatctagcctccctgatcctgtatgcctatcaactcagtactgcg
ctggcctatctagagagcaaaagatttgtgcacagggatattgctgctcgaaatgttctg
gtgtcctccaatgactgtgtaaaactaggagactttggactgtcccgatacatggaagac
agcacttactacaaagcttccaaaggaaagttgcctattaagtggatggctccagagtca
atcaattttcgacgttttacctcagctagtgacgtgtggatgtttggtgtgtgtatgtgg
gagatactcatgcacggcgtgaagccctttcaaggagtgaagaacaatgatgtgatcggc
cgaattgagaacggggagaggctgcccatgcctccaaattgccctcccaccctctacagc
cttatgacgaaatgctgggcctacgaccccagcaggcggccccggttcacagagctcaaa
gctcagctcagcacaatcctggaggaggagaaggctcagcaggaagagcggatgaggatg
gagtccagaagacaggtccctgtgtcctgggactccggaggggccgacgaagctccgccc
aagcccagcagacctggctatcccagcccaaggtccagtgaaggattttaccccagccct
cagcacatggtgcaggccaatcactaccaggtctccggctaccccggctcccatggcgtc
acagccatggccggcagcgtctaccctgggcaggcgtctctcttggaccagacagataca
tggaaccacaggccacaggaggtcgccatgtggcagcctggcgtggaggatgcagcggcc
ctggacctgcgtggagttgggcaggcactgccctcccacctgatggaagagcggctgatc
cgacagcagcaggagatggaagaagaccagcgctggctggagaaggaggagcgcttcctg
accgggaaccagcacatctaccagcctgtgggcaaaccagaccctgcagctccaccgaag
aagccgccgcgccccggagcccctggccacctgggcagcctggccagtctcggcagtccc
ggggacagctacaacgagggcgtcaagctgcagccccaggagatcagccccccgcccacc
gccaacctggaccgctccaacgacagggtgtacgagaatgtcacgggcctggtgaaggcc
gtcattgagatgtccagtaagatccagccggcgccgccagaggagtacgtgcccatggtg
aaggaagtcggcttggccctgaggacgctactggccactgtggatgagaccgtccctgcc
ctgccagccagcactcaccgagagattgagatggcccagaagctgctcaactccgacttg
ggcgagctcatcaacaagatgaaactggcccagcagtacgtgatgaccagcctgcagcag
gagtacaagaagcagatgctgactgccgcccacgccctggccgtggacgccaaaaactta
ctcgacgtcattgaccaagcaagactgaaaatgcttgggcagacgaggccgcactga
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integrated database retrieval system
