Talpa occidentalis (Iberian mole): 119242012
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Entry
119242012 CDS
T07495
Symbol
PDPK1
Name
(RefSeq) 3-phosphoinositide-dependent protein kinase 1
KO
K06276
3-phosphoinositide dependent protein kinase-1 [EC:
2.7.11.1
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod01524
Platinum drug resistance
tod03320
PPAR signaling pathway
tod04068
FoxO signaling pathway
tod04071
Sphingolipid signaling pathway
tod04140
Autophagy - animal
tod04150
mTOR signaling pathway
tod04151
PI3K-Akt signaling pathway
tod04152
AMPK signaling pathway
tod04210
Apoptosis
tod04360
Axon guidance
tod04510
Focal adhesion
tod04660
T cell receptor signaling pathway
tod04664
Fc epsilon RI signaling pathway
tod04722
Neurotrophin signaling pathway
tod04910
Insulin signaling pathway
tod04919
Thyroid hormone signaling pathway
tod04931
Insulin resistance
tod04960
Aldosterone-regulated sodium reabsorption
tod05145
Toxoplasmosis
tod05205
Proteoglycans in cancer
tod05208
Chemical carcinogenesis - reactive oxygen species
tod05213
Endometrial cancer
tod05215
Prostate cancer
tod05223
Non-small cell lung cancer
tod05231
Choline metabolism in cancer
tod05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
119242012 (PDPK1)
04071 Sphingolipid signaling pathway
119242012 (PDPK1)
04151 PI3K-Akt signaling pathway
119242012 (PDPK1)
04152 AMPK signaling pathway
119242012 (PDPK1)
04150 mTOR signaling pathway
119242012 (PDPK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
119242012 (PDPK1)
09143 Cell growth and death
04210 Apoptosis
119242012 (PDPK1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
119242012 (PDPK1)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
119242012 (PDPK1)
04664 Fc epsilon RI signaling pathway
119242012 (PDPK1)
09152 Endocrine system
04910 Insulin signaling pathway
119242012 (PDPK1)
03320 PPAR signaling pathway
119242012 (PDPK1)
04919 Thyroid hormone signaling pathway
119242012 (PDPK1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
119242012 (PDPK1)
09156 Nervous system
04722 Neurotrophin signaling pathway
119242012 (PDPK1)
09158 Development and regeneration
04360 Axon guidance
119242012 (PDPK1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
119242012 (PDPK1)
05208 Chemical carcinogenesis - reactive oxygen species
119242012 (PDPK1)
05231 Choline metabolism in cancer
119242012 (PDPK1)
09162 Cancer: specific types
05215 Prostate cancer
119242012 (PDPK1)
05213 Endometrial cancer
119242012 (PDPK1)
05223 Non-small cell lung cancer
119242012 (PDPK1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
119242012 (PDPK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
119242012 (PDPK1)
09167 Endocrine and metabolic disease
04931 Insulin resistance
119242012 (PDPK1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
119242012 (PDPK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tod01001
]
119242012 (PDPK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tod04131
]
119242012 (PDPK1)
Enzymes [BR:
tod01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
119242012 (PDPK1)
Protein kinases [BR:
tod01001
]
Serine/threonine kinases: AGC group
PDK1 family
119242012 (PDPK1)
Membrane trafficking [BR:
tod04131
]
Exocytosis
Calcium ion-dependent exocytosis
Acrosomal exocytosis proteins
119242012 (PDPK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PH_3
PK_Tyr_Ser-Thr
Kinase-like
Pkinase_fungal
FTA2
ABC1
APH
Haspin_kinase
Kdo
Motif
Other DBs
NCBI-GeneID:
119242012
NCBI-ProteinID:
XP_037363656
LinkDB
All DBs
Position
Unknown
AA seq
555 aa
AA seq
DB search
MARTTSQLYDAVPIQPSVVLCSCPSPSMVRTQTEPGTAPGAPGGGRQGPAMDGTAAESRP
GGASLQHAAQPPLQPRKKRPEDFKFGKILGEGSFSTVVLARELATSREYAIKILEKRHII
KENKAPYVTRERDVMSRLDHPFFVRLYFTFQDDEKLYFGLSYAKNGELLKYIRKIGSFDE
TCTRFYTAEMVSALEYLHGRGIIHRDLKPENILLNEDMHIQITDFGTAKVLSPESKQARA
NSFVGTAQYVSPELLTEKSACKSSDLWALGCIIYQLVAGLPPFRAGNEYLIFQKIIKLEY
DFPEKFFPKARDLVEKLLVLDATKRLGCEEMGGYSPLKAHPFFESITWENLHHQTPPKLT
AYLPAMSEDDEDCYGNYDNLLSQFGCMQVSSSSHSLSAADPGPPPRAGSNIEQYIHDLDS
NSFELDLQFSEEEKRLLLEKQASGNPWHQFVENNLILKMGPVDKRKGLFARRRQLLLTEG
PHLYYVDPVNRVLKGEIPWSQELRPEAKNFKTFFVHTPNRTYYLMDPSGNAHKWCRKIQE
VWRHRYQSPPDAAVQ
NT seq
1668 nt
NT seq
+upstream
nt +downstream
nt
atggccaggaccaccagccagctgtatgacgcggtgcccatccagcccagcgtggtgtta
tgctcctgcccgtccccatccatggtgaggacccagactgagcccggcacggcccctggc
gctcccggcggagggaggcagggccccgccatggacggcacggcggccgagtcccggccc
ggcggcgcctccctgcagcacgccgcgcagccgccactgcagcctcggaagaaacggccc
gaagatttcaaattcgggaagattcttggcgaaggctctttttccacagttgtcctggcc
cgagagctggcgacctccagagaatacgctattaaaatcctagagaaacggcacattatc
aaagagaacaaggccccgtatgtaaccagggagagagacgtcatgtcgcgcctggaccac
cccttcttcgtcaggctgtacttcaccttccaggatgacgagaagctttattttggcctt
agttacgccaaaaatggagaattacttaagtacatccgcaaaatcggctcctttgacgag
acgtgcacgcgcttctacacggccgagatggtgtcggcgctggagtacctgcacggcagg
ggcatcatccacagggacctgaagccggagaacatcttgctgaatgaggacatgcacatc
cagatcacagacttcgggaccgcgaaggtgctgtccccggagagcaagcaagccagggcc
aactccttcgtgggcacggcccagtacgtctctccagagctgctcacagagaagtcggcc
tgtaagagctcagacctgtgggccctcggctgcatcatctaccagctcgtggcgggactg
ccgcccttccgggcaggaaacgagtatcttatatttcagaagatcattaagttggaatat
gactttccggaaaaattcttccctaaggccagagacctcgtggaaaagctcctggtttta
gatgctacaaagagattaggctgtgaagaaatgggcgggtacagtcctctgaaggcccat
cccttctttgagtccattacatgggagaatctgcaccaccagacgcccccgaagctcacg
gcatacttacccgccatgtccgaagacgacgaggactgctacgggaattacgacaacctc
ctgagccagtttggctgcatgcaggtgtcctcctcctcccactccctgtctgccgcagac
ccgggcccgccccccagggccggcagcaacatcgagcagtacatccacgacctggacagc
aattcttttgaactggacttgcagttttccgaggaggagaagcggttgttgctggagaag
caggccagtgggaacccttggcaccagtttgtagaaaacaacttaatactgaagatgggc
ccagtagacaagcggaagggcttatttgcacggcggcgacagctgctgctcacggaaggg
cctcacctgtactacgtggatcctgtcaacagagtcctgaagggcgagatcccgtggtcg
caggagctccggccagaggccaagaattttaagaccttctttgtccacacgcccaacagg
acgtattacctgatggacccgagcgggaatgctcacaagtggtgcagaaagatccaggag
gtgtggcggcacagataccagagcccaccggacgctgccgtgcagtga
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