KEGG   Talpa occidentalis (Iberian mole): 119243289
Entry
119243289         CDS       T07495                                 
Symbol
IL6
Name
(RefSeq) interleukin-6
  KO
K05405  interleukin 6
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod01521  EGFR tyrosine kinase inhibitor resistance
tod01523  Antifolate resistance
tod04060  Cytokine-cytokine receptor interaction
tod04061  Viral protein interaction with cytokine and cytokine receptor
tod04066  HIF-1 signaling pathway
tod04068  FoxO signaling pathway
tod04151  PI3K-Akt signaling pathway
tod04218  Cellular senescence
tod04620  Toll-like receptor signaling pathway
tod04621  NOD-like receptor signaling pathway
tod04623  Cytosolic DNA-sensing pathway
tod04625  C-type lectin receptor signaling pathway
tod04630  JAK-STAT signaling pathway
tod04640  Hematopoietic cell lineage
tod04657  IL-17 signaling pathway
tod04659  Th17 cell differentiation
tod04668  TNF signaling pathway
tod04672  Intestinal immune network for IgA production
tod04931  Insulin resistance
tod04932  Non-alcoholic fatty liver disease
tod04933  AGE-RAGE signaling pathway in diabetic complications
tod04936  Alcoholic liver disease
tod05010  Alzheimer disease
tod05020  Prion disease
tod05022  Pathways of neurodegeneration - multiple diseases
tod05132  Salmonella infection
tod05133  Pertussis
tod05134  Legionellosis
tod05135  Yersinia infection
tod05142  Chagas disease
tod05143  African trypanosomiasis
tod05144  Malaria
tod05146  Amoebiasis
tod05152  Tuberculosis
tod05161  Hepatitis B
tod05162  Measles
tod05163  Human cytomegalovirus infection
tod05164  Influenza A
tod05166  Human T-cell leukemia virus 1 infection
tod05167  Kaposi sarcoma-associated herpesvirus infection
tod05168  Herpes simplex virus 1 infection
tod05169  Epstein-Barr virus infection
tod05171  Coronavirus disease - COVID-19
tod05200  Pathways in cancer
tod05202  Transcriptional misregulation in cancer
tod05321  Inflammatory bowel disease
tod05323  Rheumatoid arthritis
tod05332  Graft-versus-host disease
tod05410  Hypertrophic cardiomyopathy
tod05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    119243289 (IL6)
   04668 TNF signaling pathway
    119243289 (IL6)
   04066 HIF-1 signaling pathway
    119243289 (IL6)
   04068 FoxO signaling pathway
    119243289 (IL6)
   04151 PI3K-Akt signaling pathway
    119243289 (IL6)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    119243289 (IL6)
   04061 Viral protein interaction with cytokine and cytokine receptor
    119243289 (IL6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    119243289 (IL6)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    119243289 (IL6)
   04620 Toll-like receptor signaling pathway
    119243289 (IL6)
   04621 NOD-like receptor signaling pathway
    119243289 (IL6)
   04623 Cytosolic DNA-sensing pathway
    119243289 (IL6)
   04625 C-type lectin receptor signaling pathway
    119243289 (IL6)
   04659 Th17 cell differentiation
    119243289 (IL6)
   04657 IL-17 signaling pathway
    119243289 (IL6)
   04672 Intestinal immune network for IgA production
    119243289 (IL6)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119243289 (IL6)
   05202 Transcriptional misregulation in cancer
    119243289 (IL6)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    119243289 (IL6)
   05161 Hepatitis B
    119243289 (IL6)
   05171 Coronavirus disease - COVID-19
    119243289 (IL6)
   05164 Influenza A
    119243289 (IL6)
   05162 Measles
    119243289 (IL6)
   05168 Herpes simplex virus 1 infection
    119243289 (IL6)
   05163 Human cytomegalovirus infection
    119243289 (IL6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119243289 (IL6)
   05169 Epstein-Barr virus infection
    119243289 (IL6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    119243289 (IL6)
   05135 Yersinia infection
    119243289 (IL6)
   05133 Pertussis
    119243289 (IL6)
   05134 Legionellosis
    119243289 (IL6)
   05152 Tuberculosis
    119243289 (IL6)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    119243289 (IL6)
   05144 Malaria
    119243289 (IL6)
   05142 Chagas disease
    119243289 (IL6)
   05143 African trypanosomiasis
    119243289 (IL6)
  09163 Immune disease
   05323 Rheumatoid arthritis
    119243289 (IL6)
   05321 Inflammatory bowel disease
    119243289 (IL6)
   05332 Graft-versus-host disease
    119243289 (IL6)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    119243289 (IL6)
   05020 Prion disease
    119243289 (IL6)
   05022 Pathways of neurodegeneration - multiple diseases
    119243289 (IL6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    119243289 (IL6)
   05410 Hypertrophic cardiomyopathy
    119243289 (IL6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    119243289 (IL6)
   04932 Non-alcoholic fatty liver disease
    119243289 (IL6)
   04931 Insulin resistance
    119243289 (IL6)
   04933 AGE-RAGE signaling pathway in diabetic complications
    119243289 (IL6)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    119243289 (IL6)
   01523 Antifolate resistance
    119243289 (IL6)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:tod04052]
    119243289 (IL6)
Cytokines and neuropeptides [BR:tod04052]
 Cytokines
  Interleukins
   119243289 (IL6)
SSDB
Motif
Pfam: IL6 IL23 GCSF Sec16 ABC2_membrane_3
Other DBs
NCBI-GeneID: 119243289
NCBI-ProteinID: XP_037364886
LinkDB
Position
Unknown
AA seq 211 aa
MSFLSTSVFSPIAISLGLLLVMATAFPTPIPLGEDSKDVILNRAPLTSSNKTEELIKYIL
IKISALKNEMCKKYDKCDNNKEALAENNLNLPKMTAKDGCFQSGFNKETCLMRITTGLLD
FQIYLEYLQYKFEGDKENAEAVQNSTKALRQILRQKVKNPDALMIPSPTANARLLDELQS
QNEWLKNTTIHLTLQSLEDFLQFSLRAIRIM
NT seq 636 nt   +upstreamnt  +downstreamnt
atgagcttcctctccacaagcgtcttcagcccaattgccatctccctggggctgctcctg
gtgatggctactgcttttcccaccccaatacccctgggagaagattccaaagatgttatc
ctaaacagagcaccactcacctcttcaaacaaaaccgaagaactcattaaatacatcctc
atcaaaatctctgctctgaaaaatgagatgtgtaaaaagtatgacaagtgtgacaataac
aaggaggcactggcagaaaataacctgaaccttccaaaaatgacagcaaaagatggatgc
ttccaatctggattcaataaggagacctgcctgatgagaatcaccaccggtcttttggac
tttcagatatacctagagtacctccagtataagtttgaaggtgataaggaaaatgccgag
gctgtacagaacagtaccaaagccctgagacagatcctaaggcaaaaggtaaagaatcca
gatgctctcatgatccctagcccaactgcaaatgccaggctgctagatgaactgcagtca
cagaacgaatggttgaaaaacacaacaattcacctcaccctacaaagccttgaggatttc
ctgcagttcagcctgagggctattcggataatgtag

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