Talpa occidentalis (Iberian mole): 119244965
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Entry
119244965 CDS
T07495
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X2
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
tod
Talpa occidentalis (Iberian mole)
Pathway
tod04014
Ras signaling pathway
tod04072
Phospholipase D signaling pathway
tod04148
Efferocytosis
tod04360
Axon guidance
tod04625
C-type lectin receptor signaling pathway
tod04630
JAK-STAT signaling pathway
tod04650
Natural killer cell mediated cytotoxicity
tod04660
T cell receptor signaling pathway
tod04670
Leukocyte transendothelial migration
tod04722
Neurotrophin signaling pathway
tod04920
Adipocytokine signaling pathway
tod04931
Insulin resistance
tod05168
Herpes simplex virus 1 infection
tod05205
Proteoglycans in cancer
tod05208
Chemical carcinogenesis - reactive oxygen species
tod05211
Renal cell carcinoma
tod05220
Chronic myeloid leukemia
tod05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
tod00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
119244965 (PTPN11)
04630 JAK-STAT signaling pathway
119244965 (PTPN11)
04072 Phospholipase D signaling pathway
119244965 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
119244965 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
119244965 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
119244965 (PTPN11)
04660 T cell receptor signaling pathway
119244965 (PTPN11)
04670 Leukocyte transendothelial migration
119244965 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
119244965 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
119244965 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
119244965 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
119244965 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
119244965 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
119244965 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
119244965 (PTPN11)
05211 Renal cell carcinoma
119244965 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
119244965 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
119244965 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
tod01009
]
119244965 (PTPN11)
Enzymes [BR:
tod01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
119244965 (PTPN11)
Protein phosphatases and associated proteins [BR:
tod01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
119244965 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
119244965
NCBI-ProteinID:
XP_037367028
LinkDB
All DBs
Position
Unknown
AA seq
593 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGDCSDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPSDPGGVLDFLEEVHHKQEGIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLTDQTSGDQSPLPPCTPTPSCAEMREDNARVYENVGLMQQQKSFR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaatatcaccggtgtggaggcagaaaacctcctg
ttgacaagaggagtcgatggcagttttttggcgaggcctagtaagagtaaccctggagac
ttcacactttccgttagaagaaatggagcagtcacccacatcaagattcagaacactggc
gattactatgacttatatggaggggagaagtttgccactttggctgagttggtccagtat
tacatggaacaccatgggcaattaaaagagaagaatggagatgttattgagctcaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcacggacacctctctggcaaa
gaagcagagaaactactaactgagaaaggaaaacatggcagctttcttgtacgagagagc
cagagccaccctggagattttgttctctctgtccgaaccggcgatgacaaaggggattgt
agcgacggcaagtccaaagtgacccacgtcatgatccgctgtcaggaactgaaatacgat
gttggtggaggagaacggtttgactctttgacagacctcgtggagcattacaagaagaat
cccatggtggagacattgggcacggtgctccagctcaaacagcccctcaacacaactcgt
atcaatgctgctgaaatagaaagccgggttcgagaactaagcaaattagctgagaccaca
gacaaagtcaaacaaggcttttgggaagaatttgagacactacagcagcaggagtgcaag
cttctctatagccgaaaagaaggtcagaggcaagaaaataagaacaaaaatagatataaa
aacatcctaccatttgatcacaccagagttgtcctacacgatggtgatcccaatgagcca
gtctcagattacatcaacgcaaatattatcatgcctgaatttgaaaccaagtgcaacaat
tccaagcccaagaagagttacattgccacacaaggctgcctgcaaaacacagttaatgac
ttctggcggatggtgtttcaagagaactcccgagtgattgtcatgacaacgaaagaagtg
gagcgaggaaagagtaaatgtgtcaaatactggcctgacgagtatgcgctgaaagaatac
ggggtcatgcgcgttaggaacgtcaaagagagtgccgctcacgactacacattaagagaa
cttaaactttcgaaggttggacaagggaatacggagagaaccgtctggcaataccacttt
cggacctggccagaccatggagtgcccagtgaccccgggggcgtgctggacttcctggag
gaggtgcaccacaagcaggagggcatcatggacgcagggccggtggtggttcactgcagt
gctggaatcggccggacagggaccttcattgtgattgatatcctgatcgacatcatcaga
gagaaaggtgtggactgtgacatcgacgttcccaagaccattcagatggtgcggtctcag
aggtcagggatggtccagacagaagcacagtaccgattcatctacatggccgtccagcat
tacatcgaaacactacagcgcaggattgaagaagagcagaaaagcaagaggaaagggcac
gaatataccaatatcaagtattccctaacagaccagacaagcggagatcagagtcccctc
ccaccttgcacgccaacaccatcctgtgccgaaatgagagaagacaatgccagagtctat
gaaaatgtggggctgatgcagcagcagaagagcttcagatga
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