KEGG   Talpa occidentalis (Iberian mole): 119248102
Entry
119248102         CDS       T07495                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod01522  Endocrine resistance
tod04110  Cell cycle
tod04115  p53 signaling pathway
tod04151  PI3K-Akt signaling pathway
tod04218  Cellular senescence
tod04530  Tight junction
tod04660  T cell receptor signaling pathway
tod04933  AGE-RAGE signaling pathway in diabetic complications
tod04934  Cushing syndrome
tod05160  Hepatitis C
tod05162  Measles
tod05163  Human cytomegalovirus infection
tod05164  Influenza A
tod05165  Human papillomavirus infection
tod05166  Human T-cell leukemia virus 1 infection
tod05167  Kaposi sarcoma-associated herpesvirus infection
tod05169  Epstein-Barr virus infection
tod05200  Pathways in cancer
tod05203  Viral carcinogenesis
tod05212  Pancreatic cancer
tod05214  Glioma
tod05218  Melanoma
tod05219  Bladder cancer
tod05220  Chronic myeloid leukemia
tod05222  Small cell lung cancer
tod05223  Non-small cell lung cancer
tod05224  Breast cancer
tod05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    119248102 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    119248102 (CDK4)
   04115 p53 signaling pathway
    119248102 (CDK4)
   04218 Cellular senescence
    119248102 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    119248102 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    119248102 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119248102 (CDK4)
   05203 Viral carcinogenesis
    119248102 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    119248102 (CDK4)
   05225 Hepatocellular carcinoma
    119248102 (CDK4)
   05214 Glioma
    119248102 (CDK4)
   05220 Chronic myeloid leukemia
    119248102 (CDK4)
   05218 Melanoma
    119248102 (CDK4)
   05219 Bladder cancer
    119248102 (CDK4)
   05224 Breast cancer
    119248102 (CDK4)
   05222 Small cell lung cancer
    119248102 (CDK4)
   05223 Non-small cell lung cancer
    119248102 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    119248102 (CDK4)
   05160 Hepatitis C
    119248102 (CDK4)
   05164 Influenza A
    119248102 (CDK4)
   05162 Measles
    119248102 (CDK4)
   05163 Human cytomegalovirus infection
    119248102 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    119248102 (CDK4)
   05169 Epstein-Barr virus infection
    119248102 (CDK4)
   05165 Human papillomavirus infection
    119248102 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    119248102 (CDK4)
   04934 Cushing syndrome
    119248102 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    119248102 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tod01001]
    119248102 (CDK4)
Enzymes [BR:tod01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     119248102 (CDK4)
Protein kinases [BR:tod01001]
 Serine/threonine kinases: CMGC group
  CDK family
   119248102 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo APH ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 119248102
NCBI-ProteinID: XP_037370978
LinkDB
Position
Unknown
AA seq 302 aa
MATSRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGDGAGGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MCQFLRGLEFLHANSIVHRDLKPENILVTSSGTVKLADFGLARIYSYQMALTPVVVTLWY
RAPEVLLQSTYATPVDMWSVGCIFAEMFRRRPLFCGNSEADQLGKIFDLIGLPPEEDWPR
DVSLPRGAFSPRGPRPVQSVVPEMEEAGAQLLLEMLAFNPHKRISALRALQHCYLQKEGN
PE
NT seq 909 nt   +upstreamnt  +downstreamnt
atggctacctcgcgatacgagccagtggccgagattggcgtcggtgcctatgggactgtg
tacaaagcccgcgaccctcacagtggccactttgtggccctcaagagcgtgagagtcccc
aacggagacggtgctggagggggcctccccatcagcacagtgcgggaggttgcgttactg
aggcgactggaggcttttgagcatcctaatgtggtccggctgatggacgtctgcgccact
gcacgaacggatcgggagaccaaagtgaccctggtgtttgagcatgtggaccaggacctc
aggacgtatctggacaaggcacccccgccaggcttgccagtggagaccattaaggatctg
atgtgccagtttctaagaggcctagaattccttcatgccaacagcatcgtccaccgagac
ctgaagccagagaacattctggtgacaagcagtggaacagtcaagctggctgacttcggc
ctagccaggatctacagctaccagatggcgctcacaccagtggttgtgacactctggtac
cgggccccggaggtgcttctgcagtctacgtatgcaacacccgtggacatgtggagcgtt
ggctgtatctttgcagagatgttccgccgaaggcctctcttctgtggaaactctgaagct
gaccagttgggcaagatctttgacctgattgggctgccgccagaagaggactggccccga
gatgtgtctctgccccgcggagccttttcccccagagggccccgcccagtgcagtctgtg
gtgcccgagatggaggaggctggagcgcagctgctgctggagatgctggcttttaaccca
cacaagcgaatctctgctctccgagccctgcagcactgttacctacaaaaagaaggtaac
ccagagtga

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