KEGG   Talpa occidentalis (Iberian mole): 119249350
Entry
119249350         CDS       T07495                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X1
  KO
K13375  transforming growth factor beta-1
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod04010  MAPK signaling pathway
tod04060  Cytokine-cytokine receptor interaction
tod04068  FoxO signaling pathway
tod04110  Cell cycle
tod04148  Efferocytosis
tod04218  Cellular senescence
tod04350  TGF-beta signaling pathway
tod04380  Osteoclast differentiation
tod04390  Hippo signaling pathway
tod04659  Th17 cell differentiation
tod04672  Intestinal immune network for IgA production
tod04926  Relaxin signaling pathway
tod04932  Non-alcoholic fatty liver disease
tod04933  AGE-RAGE signaling pathway in diabetic complications
tod05140  Leishmaniasis
tod05142  Chagas disease
tod05144  Malaria
tod05145  Toxoplasmosis
tod05146  Amoebiasis
tod05152  Tuberculosis
tod05161  Hepatitis B
tod05166  Human T-cell leukemia virus 1 infection
tod05200  Pathways in cancer
tod05205  Proteoglycans in cancer
tod05210  Colorectal cancer
tod05211  Renal cell carcinoma
tod05212  Pancreatic cancer
tod05220  Chronic myeloid leukemia
tod05225  Hepatocellular carcinoma
tod05226  Gastric cancer
tod05321  Inflammatory bowel disease
tod05323  Rheumatoid arthritis
tod05410  Hypertrophic cardiomyopathy
tod05414  Dilated cardiomyopathy
tod05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119249350 (TGFB1)
   04350 TGF-beta signaling pathway
    119249350 (TGFB1)
   04390 Hippo signaling pathway
    119249350 (TGFB1)
   04068 FoxO signaling pathway
    119249350 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    119249350 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    119249350 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    119249350 (TGFB1)
   04218 Cellular senescence
    119249350 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    119249350 (TGFB1)
   04672 Intestinal immune network for IgA production
    119249350 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    119249350 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    119249350 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119249350 (TGFB1)
   05205 Proteoglycans in cancer
    119249350 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    119249350 (TGFB1)
   05212 Pancreatic cancer
    119249350 (TGFB1)
   05225 Hepatocellular carcinoma
    119249350 (TGFB1)
   05226 Gastric cancer
    119249350 (TGFB1)
   05220 Chronic myeloid leukemia
    119249350 (TGFB1)
   05211 Renal cell carcinoma
    119249350 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    119249350 (TGFB1)
   05161 Hepatitis B
    119249350 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    119249350 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    119249350 (TGFB1)
   05144 Malaria
    119249350 (TGFB1)
   05145 Toxoplasmosis
    119249350 (TGFB1)
   05140 Leishmaniasis
    119249350 (TGFB1)
   05142 Chagas disease
    119249350 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    119249350 (TGFB1)
   05321 Inflammatory bowel disease
    119249350 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    119249350 (TGFB1)
   05414 Dilated cardiomyopathy
    119249350 (TGFB1)
   05415 Diabetic cardiomyopathy
    119249350 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    119249350 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    119249350 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:tod03110]
    119249350 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:tod04052]
    119249350 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:tod00536]
    119249350 (TGFB1)
Chaperones and folding catalysts [BR:tod03110]
 Intramolecular chaperones
  Others
   119249350 (TGFB1)
Cytokines and neuropeptides [BR:tod04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   119249350 (TGFB1)
Glycosaminoglycan binding proteins [BR:tod00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   119249350 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 119249350
NCBI-ProteinID: XP_037372525
LinkDB
Position
Unknown
AA seq 392 aa
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGDVPPGPLPETVLALYNSTRDRVAGERAEPEPEPEADYYAKEVSRVLMVEYGNEI
YKKIKSGSHSIYMLFNTSELREAVPDPLLLSRAELRLQRQKLNTEQRVELYQKYSNNTWR
YLSNRLLAPSDTPEWLSFDVTGVVRQWLSHGAGEIEGFRLSAHCSCDNSNNTLQVEINAG
FSSSLRGDLATIRGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQL
YIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVP
QVLEPLPIVYYVGRKAKVEQLTNMIVRSCKCS
NT seq 1179 nt   +upstreamnt  +downstreamnt
atgccgccctcggggctgcggctgctgccgctgctgctgccgctgctgtggctgctcgtg
ctgacccccggccggccggccgccggcctctccacctgcaagaccatcgacatggagctg
gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgcc
agccccccgagccagggcgacgtgccgccgggcccgctgccggagacggtgctggcgctg
tacaacagcacccgcgaccgggtggccggggagagggccgagcccgagcccgagcccgag
gccgactactacgccaaggaggtctcccgcgtgctcatggtggagtacggcaacgaaatc
tataaaaaaatcaagtctggctctcacagcatatacatgctcttcaacacgtcagagctc
cgggaagcggtgcctgatcccttgttgctgtcccgggcagagctgcgcctgcagaggcaa
aaactgaacacagagcagcgcgtggagctgtaccagaaatatagcaataatacctggcgc
tacctcagcaaccggctactggcccccagcgacacgccggagtggctgtcctttgatgtc
actggagttgtgcggcaatggctgagccacggagcaggggaaatagagggctttcgactc
agtgcccactgttcctgtgacaacagcaataacacactccaagtggaaatcaacgcaggg
ttcagctccagtctccggggcgacctggccaccattcgtggcatgaaccggcctttcctg
ctcctcatggccaccccgctggagagggcccagcacctgcacagctcccggcaccgccga
gccctggacaccaactactgcttcagctccacagaaaagaactgctgtgtgcggcagctt
tacatcgacttccgcaaggacctgggctggaagtggatccacgagcctaagggctaccat
gccaacttctgcctggggccctgcccctacatctggagcctggacacacagtacagcaag
gtcctggccctgtacaaccagcacaacccgggcgcgtcggcagcgccgtgctgcgtgccg
caggtgctcgagccgctgcccatcgtgtactacgtgggccgcaaggccaaggtggagcag
ctgaccaacatgatcgtgcgctcctgcaagtgcagctga

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