KEGG   Talpa occidentalis (Iberian mole): 119255656
Entry
119255656         CDS       T07495                                 
Symbol
PAK1
Name
(RefSeq) serine/threonine-protein kinase PAK 1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod04010  MAPK signaling pathway
tod04012  ErbB signaling pathway
tod04014  Ras signaling pathway
tod04024  cAMP signaling pathway
tod04062  Chemokine signaling pathway
tod04360  Axon guidance
tod04392  Hippo signaling pathway - multiple species
tod04510  Focal adhesion
tod04625  C-type lectin receptor signaling pathway
tod04650  Natural killer cell mediated cytotoxicity
tod04660  T cell receptor signaling pathway
tod04666  Fc gamma R-mediated phagocytosis
tod04810  Regulation of actin cytoskeleton
tod05132  Salmonella infection
tod05170  Human immunodeficiency virus 1 infection
tod05205  Proteoglycans in cancer
tod05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119255656 (PAK1)
   04012 ErbB signaling pathway
    119255656 (PAK1)
   04014 Ras signaling pathway
    119255656 (PAK1)
   04392 Hippo signaling pathway - multiple species
    119255656 (PAK1)
   04024 cAMP signaling pathway
    119255656 (PAK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    119255656 (PAK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    119255656 (PAK1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    119255656 (PAK1)
   04650 Natural killer cell mediated cytotoxicity
    119255656 (PAK1)
   04660 T cell receptor signaling pathway
    119255656 (PAK1)
   04666 Fc gamma R-mediated phagocytosis
    119255656 (PAK1)
   04062 Chemokine signaling pathway
    119255656 (PAK1)
  09158 Development and regeneration
   04360 Axon guidance
    119255656 (PAK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    119255656 (PAK1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    119255656 (PAK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    119255656 (PAK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    119255656 (PAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tod01001]
    119255656 (PAK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tod04131]
    119255656 (PAK1)
   03036 Chromosome and associated proteins [BR:tod03036]
    119255656 (PAK1)
Enzymes [BR:tod01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     119255656 (PAK1)
Protein kinases [BR:tod01001]
 Serine/threonine kinases: STE group
  STE20 family
   119255656 (PAK1)
Membrane trafficking [BR:tod04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    119255656 (PAK1)
 Endocytosis
  Macropinocytosis
   Kinases
    119255656 (PAK1)
Chromosome and associated proteins [BR:tod03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     119255656 (PAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT
Other DBs
NCBI-GeneID: 119255656
NCBI-ProteinID: XP_037378919
LinkDB
Position
Unknown
AA seq 544 aa
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGTLNHGSKPLPPNPEEKKKKDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKLAEDYNSSNTLNVKTVSETPAVPPVSEDEDDD
DDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNAAPPDTLTRNTEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSAIFRDFLNRCLEMDVERRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNNH
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgtcaaataacggcctcgacattcaagataaacccccagcccctcccatgagaaacact
agcactatgattggcgctggcagcaaagatgctggaaccctaaaccatggttccaaacct
ctgcccccaaacccagaggagaagaaaaagaaggaccgattttaccgatccatcttgcct
ggagataaaacaaataaaaagaaggagaaagaacgaccagagatatctcttccttcagat
tttgagcacacaattcatgttggttttgatgctgtcacaggggagtttacggggatgcca
gagcagtgggctcgcttgcttcaaacatcaaatatcactaagtcagagcagaagaaaaac
ccgcaagctgtactggatgtattggaattttataactcaaagaagacttccaatagccag
aagtacatgagctttacagataaattagctgaggattataattcatccaacactttgaat
gtgaagacagtatctgagactccagcagtgcctccagtttcagaagatgaagatgatgat
gatgatgctaccccacctccagtgattgctcctcgcccagagcatacaaaatctgtatac
acacggtccgtgattgaaccacttcctgttactccaactcgggacgtggctacatctccc
atttcacctactgagaataatgctgctccaccagatactctcactcggaatactgagaaa
cagaagaagaaacctaaaatgtctgatgaggagattttggagaaattacgcagcatagtg
agtgtgggcgatcctaagaagaaatatacacgatttgagaagattggacaaggtgcttcg
ggcaccgtgtacactgcaatggatgtggccacagggcaggaggtggctattaagcagatg
aaccttcagcagcagccgaagaaagaactgattattaatgagatcctggtcatgagggaa
aacaagaacccaaatattgtgaactatttggacagttacctggtgggggatgaactgtgg
gttgtcatggaatacttggctggaggctctttgacagatgtggtgacagaaacctgcatg
gatgaaggccagattgcagctgtatgccgtgagtgcctgcaggctctggagtttctacat
tcaaaccaggtcattcacagagatatcaagagtgacaacatcctcttgggaatggatggc
tctgtcaagctcactgatttcggattctgtgcccagatcaccccagagcagagcaaacgg
agcaccatggtgggaaccccatactggatggcgccagaggttgtaactcggaaggcctat
ggacccaaggttgacatttggtccctgggcatcatggccattgagatgattgaaggggag
cccccatacctcaatgaaaaccctctgagagccctgtacctcattgccacaaatgggacc
ccagagcttcagaatccagagaaactatcagctatcttccgggactttctgaaccgctgt
cttgagatggatgtagagaggagaggttccgctaaagagctgctgcagcatcagttcctg
aagattgccaagcccctctccagcctcactccactgattgctgcagcaaaggaggcaact
aagaacaatcactaa

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