Talpa occidentalis (Iberian mole): 119256101 Help Entry 119256101         CDS       T07495                                  Symbol CASP8 Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism tod  Talpa occidentalis (Iberian mole) Pathway tod01524   Platinum drug resistance tod04115   p53 signaling pathway tod04210   Apoptosis tod04215   Apoptosis - multiple species tod04217   Necroptosis tod04620   Toll-like receptor signaling pathway tod04621   NOD-like receptor signaling pathway tod04622   RIG-I-like receptor signaling pathway tod04623   Cytosolic DNA-sensing pathway tod04625   C-type lectin receptor signaling pathway tod04657   IL-17 signaling pathway tod04668   TNF signaling pathway tod04932   Non-alcoholic fatty liver disease tod04936   Alcoholic liver disease tod05010   Alzheimer disease tod05016   Huntington disease tod05022   Pathways of neurodegeneration - multiple diseases tod05132   Salmonella infection tod05134   Legionellosis tod05142   Chagas disease tod05145   Toxoplasmosis tod05152   Tuberculosis tod05160   Hepatitis C tod05161   Hepatitis B tod05162   Measles tod05163   Human cytomegalovirus infection tod05164   Influenza A tod05165   Human papillomavirus infection tod05167   Kaposi sarcoma-associated herpesvirus infection tod05168   Herpes simplex virus 1 infection tod05169   Epstein-Barr virus infection tod05170   Human immunodeficiency virus 1 infection tod05200   Pathways in cancer tod05203   Viral carcinogenesis tod05416   Viral myocarditis tod05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:tod00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     119256101 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     119256101 (CASP8)    04215 Apoptosis - multiple species     119256101 (CASP8)    04217 Necroptosis     119256101 (CASP8)    04115 p53 signaling pathway     119256101 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     119256101 (CASP8)    04621 NOD-like receptor signaling pathway     119256101 (CASP8)    04622 RIG-I-like receptor signaling pathway     119256101 (CASP8)    04623 Cytosolic DNA-sensing pathway     119256101 (CASP8)    04625 C-type lectin receptor signaling pathway     119256101 (CASP8)    04657 IL-17 signaling pathway     119256101 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     119256101 (CASP8)    05203 Viral carcinogenesis     119256101 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     119256101 (CASP8)    05161 Hepatitis B     119256101 (CASP8)    05160 Hepatitis C     119256101 (CASP8)    05164 Influenza A     119256101 (CASP8)    05162 Measles     119256101 (CASP8)    05168 Herpes simplex virus 1 infection     119256101 (CASP8)    05163 Human cytomegalovirus infection     119256101 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     119256101 (CASP8)    05169 Epstein-Barr virus infection     119256101 (CASP8)    05165 Human papillomavirus infection     119256101 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     119256101 (CASP8)    05134 Legionellosis     119256101 (CASP8)    05152 Tuberculosis     119256101 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     119256101 (CASP8)    05142 Chagas disease     119256101 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     119256101 (CASP8)    05016 Huntington disease     119256101 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     119256101 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     119256101 (CASP8)    05416 Viral myocarditis     119256101 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     119256101 (CASP8)    04932 Non-alcoholic fatty liver disease     119256101 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     119256101 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:tod01002]     119256101 (CASP8) Enzymes [BR:tod01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      119256101 (CASP8) Peptidases and inhibitors [BR:tod01002]  Cysteine peptidases   Family C14: caspase family    119256101 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED DUF943 Motif Other DBs NCBI-GeneID:  119256101 NCBI-ProteinID:  XP_037379726 LinkDB All DBs Position Unknown AA seq 487 aa AA seqDB search MDDFNSCLYNIGEELDSKEVASLKFLSLDYIPPKKQEPIKDALALFQRLQEKRMLEESNL SFLKELLFRIDRWDLLKKHLNTDKEEMKQELQIPSRAQISAYRVMLFQISEGLDDPKVKE FKFFLHEKIPKCKLDDDMNLFDVFIEMEKRVILGNRNLDYLKFICDRIDKSLLKIINNYE ELSEDARMSLERNPDELSNEEPQLLTGQRSFAMLAMSDSPGQQDSDTQTSDKIYQMKSKP RGYCLIFNNYDFSQAREDVPKLYKMKDRTGTKLDAVALEETFNHLHFEVIIYNDCTAEKI CETLKTYQLMDHTSKDCFVCCILSHGDKGIIYGCDGQEASICDLISYFTGSKCPSLAGKP KIFFIQACQGENYQKGIVVETDSEQNEGYLEMDSSLQMRYIPDEADFLLGMATVNNCVSY RNPMEGTWYIQSLCQSLRERCPRGEDILTILTGVNYEVSNKDDKKNMGKQMPQPTFTLRK KLFFPLN NT seq 1464 nt NT seq  +upstreamnt  +downstreamnt atggatgatttcaacagttgtctttataatattggggaagagctggatagcaaagaggtg gcctccctcaagttcctgagcctggattacatcccgccaaagaagcaggaacccatcaag gatgccttggcattattccagagactccaggaaaaaagaatgttggaggaaagcaaccta tccttcttgaaggagttgctttttcgaattgacagatgggatctgctgaagaaacatctg aacactgataaggaggagatgaagcaggagcttcagatacccagcagggcccagatctct gcctacagggtcatgctttttcagatttcagaaggattagatgaccccaaagtgaaggaa tttaagttttttttgcatgagaagatcccaaaatgtaagctggatgatgacatgaatctg tttgatgttttcatagaaatggaaaaaagggtcatcttagggaacagaaacttggactac ttaaaatttatctgtgaccgtatcgacaagagcttgttgaagataatcaataattatgaa gaactgagcgaagatgcaagaatgagtcttgaaagaaacccagatgaactttcaaatgag gagccccagttgctcacaggacagaggtcctttgcaatgctggcaatgtccgactctccg ggacaacaggacagtgacacacagacatcagacaaaatttaccaaatgaaaagcaaacct cggggatactgtttgatctttaacaattatgacttcagccaagcacgtgaggatgtgccc aaactttataagatgaaggataggactggaacaaaattggatgcagtggctttggaggag acctttaatcatcttcattttgaggtaattatatacaatgactgcacagcagagaaaatc tgtgaaactctgaaaacctaccaactcatggatcacactagcaaggactgcttcgtttgc tgcatcctctcacatggagacaaaggcatcatctatggctgtgatgggcaggaagcctcc atctgtgatctgatctcttacttcactggttccaaatgcccttcccttgcaggcaaaccc aaaatcttttttattcaggcttgtcaaggagaaaactaccagaaaggtatagttgttgag actgactctgaacagaatgaaggctatttagaaatggattcatcacttcagatgagatat atcccagatgaagctgactttctgctggggatggccactgtgaacaactgtgtttcctac cgaaaccctatggaggggacctggtatatccagtcactttgtcagagcctgagagaacga tgtcctaggggtgaagatattcttaccatcctcaccggagtcaactatgaagtgagcaat aaggatgacaaaaaaaatatggggaaacagatgccacaacctactttcacactgaggaaa aaactcttcttccctcttaattga

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