KEGG   Talpa occidentalis (Iberian mole): 119260900
Entry
119260900         CDS       T07495                                 
Symbol
FGFR3
Name
(RefSeq) LOW QUALITY PROTEIN: fibroblast growth factor receptor 3
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod01521  EGFR tyrosine kinase inhibitor resistance
tod04010  MAPK signaling pathway
tod04014  Ras signaling pathway
tod04015  Rap1 signaling pathway
tod04020  Calcium signaling pathway
tod04144  Endocytosis
tod04151  PI3K-Akt signaling pathway
tod04550  Signaling pathways regulating pluripotency of stem cells
tod04810  Regulation of actin cytoskeleton
tod05200  Pathways in cancer
tod05206  MicroRNAs in cancer
tod05219  Bladder cancer
tod05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:tod00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    119260900 (FGFR3)
   04014 Ras signaling pathway
    119260900 (FGFR3)
   04015 Rap1 signaling pathway
    119260900 (FGFR3)
   04020 Calcium signaling pathway
    119260900 (FGFR3)
   04151 PI3K-Akt signaling pathway
    119260900 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    119260900 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    119260900 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    119260900 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    119260900 (FGFR3)
   05206 MicroRNAs in cancer
    119260900 (FGFR3)
   05230 Central carbon metabolism in cancer
    119260900 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    119260900 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    119260900 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tod01001]
    119260900 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:tod04090]
    119260900 (FGFR3)
Enzymes [BR:tod01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     119260900 (FGFR3)
Protein kinases [BR:tod01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   119260900 (FGFR3)
CD molecules [BR:tod04090]
 Proteins
  119260900 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set FGFR3_TM C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 119260900
NCBI-ProteinID: XP_054544117
LinkDB
Position
Unknown
AA seq 785 aa
MPLSAEASGPEPGIQEQLVFGSGDTVRLSCPVPAGVPVGPTIWVKDGAGLVPSARVLVGS
QQLQVLNASQEDAGAYSCRQRLTQRALCRFRVRVAEAPSSGDDEDGEDETEDAGAPFWTR
PERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVM
ESVVPSDRGNYTCIVENKFGSIQQTYMLDVLERSPHRPILQAGLPANQTAVLGSDVEFQC
KVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKSWISESVEADARLRLANVSERDGGE
YLCRATNFIGVAEKAFWLRVHEPRAAEEELVEAGEAGGVYAGVLSYGAGFLLFVLVVAAV
VLCRLHRPPKKGLGSPAVHRVSRFPLKRQVSLESDSSMNSNTPLVRVARLSSGEGPALAN
VSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAVGIDKDRAARPVTVAVKMLKDD
ATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREYLRARRPP
GMDYSFDTCKLPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKI
ADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWETFTXGGS
PYPGIPVEELFKLLREGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRILT
VTSTDEYLDLSVPFEQYSPGGQDTPSSGSSGDDSVFAHDLLSPRPLAAGALGREGLPACG
RAPPM
NT seq 2358 nt   +upstreamnt  +downstreamnt
atgcccctctccgcagaggcctcggggccggagccgggcatccaggagcagctggtcttt
ggcagcggtgacaccgtgcggctgagctgccccgtgccggcaggcgtccctgtaggaccc
accatctgggtcaaggacggggcggggctggtgccctcggcccgcgtcctggtggggtcg
cagcagctgcaggtgctcaatgcctcccaggaggacgccggggcctacagctgccggcag
cggctcacccagcgtgccctgtgccgcttccgcgtgcgggtggcagaggccccgtcctcg
ggagacgacgaagatggagaggacgagacggaagacgcaggggcccctttctggacgcgg
cctgagcggatggacaagaagctgctggctgtgccggccgccaacaccgtgcgcttccgc
tgcccggccgccggcaaccccaccccgtccatctcctggctgaagaacggcaaggagttc
cggggcgagcaccgcatcgggggcatcaagctgcggcaccagcagtggagcctggtcatg
gagagcgtggtgccctcggaccgcggcaactacacgtgcatcgtggagaacaagttcggc
agcatccagcagacctacatgctggacgtgctggagcgctccccgcaccggcccatcctg
caggcggggctgccggccaaccagacggcggtgctgggcagcgacgtggagttccagtgc
aaggtgtacagcgacgcgcagccccacatccagtggctgaagcatgtggaggtgaacggc
agcaaggtggggcccgacggcaccccgtacgtcacggtgctcaagtcctggatcagtgag
agtgtggaggctgacgcgcgcctccgcctggccaatgtgtccgagcgcgacgggggcgag
tacctctgtcgagccaccaatttcataggcgtggctgagaaggccttttggctgcgtgtg
cacgagccccgagcagccgaggaggagctggtggaggcgggagaggccggtggcgtgtac
gcgggcgtcctcagctacggggccggcttcctcctcttcgtcctggtggtggctgccgtg
gtgctctgccgcctgcacaggccgcccaagaagggcctgggctcgcccgcggtgcacaga
gtctcccgcttcccgctcaagcgacaggtgtccctggagtccgactcgtccatgaactcc
aacacccccctggtgcgcgtcgcccgcctgtcctcgggggagggccctgcgctggccaat
gtctcagagctggagctgcctgccgaccccaagtgggagctgtcccgggcccggctgacc
ctgggcaagccccttggggagggctgcttcggccaggtggtcatggcggaggcggttggc
attgacaaggaccgggcggccaggcccgtcaccgtggcggtgaagatgctgaaagacgac
gccactgacaaggacctgtcggacctggtgtcggagatggagatgatgaagatgatcggc
aagcacaagaacatcatcaacctgctgggggcctgcacgcagggcgggcccctgtacgtg
ctggtggagtacgcggccaagggcaacctgcgcgagtacctgcgcgcgcgccggccgccg
ggcatggactactccttcgacacgtgcaagctgcccgaggagcagctgaccttcaaggac
ctggtgtcctgcgcctaccaggtggcgcgcggcatggagtacctggcctcgcagaagtgc
atccaccgggacctggcggcccgcaacgtgctggtgaccgaggacaacgtgatgaagatc
gcggacttcgggctggcccgcgacgtgcacaacctggactactacaagaagaccaccaac
ggccggctgcccgtcaagtggatggcgcccgaggccctgttcgaccgcgtctacacccac
cagagcgacgtctggtcctttggggtcctgctctgggagaccttcaccnctgggggctcg
ccgtaccccggcatccccgtggaggagctgttcaagctgctgcgggagggccaccgcatg
gacaagccggccaactgcacgcacgacctgtacatgatcatgcgggagtgctggcacgcg
gcgccgtcccagaggcccaccttcaagcagctggtggaggacctggaccgcatcctcacc
gtgacgtcgaccgacgagtacctggacctgtcggtgcccttcgagcagtactcgccgggc
ggccaggacacccccagctccggctcctcgggggacgactccgtgtttgcccacgacctg
ctgtccccgcgtcccctggcagcgggggccctaggacgtgaagggctgccggcctgcggc
cgagccccaccaatgtga

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