KEGG   Talpa occidentalis (Iberian mole): 119260947
Entry
119260947         CDS       T07495                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase isoform X1
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
tod  Talpa occidentalis (Iberian mole)
Pathway
tod00670  One carbon pool by folate
tod00790  Folate biosynthesis
tod01100  Metabolic pathways
tod01240  Biosynthesis of cofactors
tod01523  Antifolate resistance
tod04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:tod00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    119260947 (DHFR)
   00670 One carbon pool by folate
    119260947 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    119260947 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    119260947 (DHFR)
Enzymes [BR:tod01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     119260947 (DHFR)
SSDB
Motif
Pfam: DHFR_1 VWA_3
Other DBs
NCBI-GeneID: 119260947
NCBI-ProteinID: XP_037385990
LinkDB
Position
Unknown
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFNYFRRMTTTSSVEGKQNLVIMGRKTWFS
IPEKSRPLKDRINLVLSRELKEPPLGAHYLAKSLDDALKLIQQPELTNKVDMVWIVGGSS
VYKEVMNKPGHVRLFVTRIMQEFESDTFFPEIDLKKYKLLPEYPGVLSDVQEEKGIKYKF
EVYEKND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctcaactgcatcgtcgcggtgtcccagaacatgggcatcggcaagaac
ggggacctgccctggcccccgctcagaaatgaattcaattatttccgaagaatgaccaca
acttcctcagtggaaggtaaacagaatttggtgattatgggtaggaagacttggttctcc
attcctgagaaaagtcggcctttaaaagacagaattaatttagttctcagtagagaactc
aaggaacctccactaggagctcattatcttgccaaaagtctggatgatgccttaaaactt
atccagcaaccagaattaacaaacaaagtagacatggtttggatagtgggaggcagttct
gtttataaggaagtcatgaataaaccaggccatgttagactgtttgtgacaagaatcatg
caagaatttgaaagtgacacattttttccagaaattgatttgaagaaatataaacttctc
ccagaatacccaggtgttctttctgatgtccaggaagagaaaggcattaagtacaaattt
gaagtttatgaaaagaatgattaa

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