KEGG   Treponema primitia: TREPR_2640
Entry
TREPR_2640        CDS       T01507                                 
Symbol
ligA
Name
(GenBank) DNA ligase (NAD(+))
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
tpi  Treponema primitia
Pathway
tpi03030  DNA replication
tpi03410  Base excision repair
tpi03420  Nucleotide excision repair
tpi03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:tpi00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    TREPR_2640 (ligA)
   03410 Base excision repair
    TREPR_2640 (ligA)
   03420 Nucleotide excision repair
    TREPR_2640 (ligA)
   03430 Mismatch repair
    TREPR_2640 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:tpi03032]
    TREPR_2640 (ligA)
   03400 DNA repair and recombination proteins [BR:tpi03400]
    TREPR_2640 (ligA)
Enzymes [BR:tpi01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     TREPR_2640 (ligA)
DNA replication proteins [BR:tpi03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     TREPR_2640 (ligA)
DNA repair and recombination proteins [BR:tpi03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     TREPR_2640 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     TREPR_2640 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     TREPR_2640 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      TREPR_2640 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden HHH_5 DNA_ligase_OB BRCT HHH_2 HHH_3 RNA_ligase PTCB-BRCT HHH IMS_HHH_1 DNA_ligase_ZBD
Other DBs
NCBI-ProteinID: AEF85331
UniProt: F5YR93
LinkDB
Position
1537752..1539722
AA seq 656 aa
MTRKDDRAAALERLIKGYQDSYYNGEAEISDAEFDALWDELKGLKPDSAVLLRVGEDNID
GFPKARHLIPMGSQEKAANPLEFRAWAEKMAPPSFVVQYKLDGASLELQYEKGKLLRAIT
RGDGVIGDEITRNARRMSGVAAELDIPFSGGIRGEVVMTHQVWREKYADKANCRNAANGL
MRRKDGVGCEDLSLIAYDAAAKDDDSYFTDELSKIAWLKDRGFSVTETREFATAEDVIVY
REKIAEERKGLSVDIDGLVIKDPRTDMTDLRRARPEMQIAFKFDLEVAVSVLREVVWSKS
GATYTPIGIVDPVRLAGTTVQRANLNNPDMIRGMGLKIGSPVRVVKRGEIIPKIEGLAPA
LPAGNDAVEETDISFPVECETCGTELVDIGTRLYCPNLGCPKRLLHRLEKWVSVLDIREL
GEKLIYQLFETERVRQISELYTLETAELSELERMGEQSAAKVVRHIRTKRDLSLAAFIAG
FDFDGVGETIMEKVTAAGFDTLEKIRSASVEKLAEVYGLGEITARTIVEGLADTGEEMDR
ILANGVISIAAPPRAEDQPLQGCSFCFTGELSSMKRNQAEEKVKTLGGSSKSSVVKDLSF
LVTNDPGSGSAKNAKARSLGIPIIDEEGFLAILADPAKVKAYSPAGGVGALQGELF
NT seq 1971 nt   +upstreamnt  +downstreamnt
atgacaagaaaagatgacagggccgctgctctggaaagattgattaaagggtatcaggat
tcctactacaatggggaagctgagatatcagacgccgaatttgatgccctttgggacgaa
ttaaaaggcctgaaaccggatagcgcagttttactgcgggttggagaagacaatattgac
gggttccccaaagcccggcatctgattcccatgggcagccaggagaaggctgcaaacccc
cttgaattccgggcctgggctgaaaaaatggctcccccttcctttgtggtgcagtataaa
ctggatggggcaagccttgaacttcagtatgaaaaaggaaaactcctgcgggcaattacc
cggggtgacggggtgattggggacgaaattacccggaacgcccggcgtatgtccggggtt
gcggcggaactggatatccccttttcaggcggcatcaggggagaggtggtgatgacccac
caggtctggcgggaaaagtacgccgacaaggccaactgccggaatgccgccaacgggctc
atgcgccgcaaggatggtgtgggctgcgaggacctttccctcattgcctatgacgccgcc
gcaaaggatgatgacagttattttaccgatgaactttccaaaatagcctggcttaaggac
cggggcttttcggtaaccgaaacccgggaatttgccactgcagaggatgtgatagtttac
cgggaaaaaatagccgaggaacggaagggcctttctgtggacatcgacgggctggtgata
aaggacccccgcacggacatgaccgatctccggcgcgccaggccggaaatgcagattgcc
ttcaagtttgatctggaggtggcggtaagtgtactgcgggaagtggtttggagcaaatcc
ggcgccacctatacccccatcggcattgtagacccggtgcggcttgcggggaccacggtc
cagcgggccaacctcaacaaccccgacatgatccggggtatggggctgaagattggttct
ccggtgcgggtggtaaagcggggggagatcatccccaagattgaagggcttgccccggcc
ttgcctgcgggcaatgatgctgttgaagaaacggatatcagctttcctgttgagtgtgaa
acctgcggcacagaactggtggatatcggtacccggctttactgtcccaaccttgggtgc
cccaagcggctccttcaccggcttgaaaagtgggtttcggttttggatatccgtgagttg
ggggaaaagttgatttaccagctctttgaaacggaacgggtccgccaaatttcggaactc
tatactctggaaacggcggaactttctgaattggaacgcatgggtgaacagtctgctgcc
aaggtggtccgccatatcaggaccaagcgggacttgtccctggctgcctttattgcaggg
tttgactttgacggggtgggggagaccatcatggagaaagttaccgccgcagggtttgac
accctggaaaaaatacgttcagcttcggtagaaaaactggccgaagtttatggtctggga
gaaatcactgcccgcaccattgttgagggtcttgcggataccggggaagaaatggatagg
atacttgccaatggggtcatcagtattgctgcgccacccagggcagaagatcagcctttg
cagggttgctccttctgttttaccggggagctcagttccatgaaacggaaccaggctgag
gaaaaggtcaaaaccctgggaggctcctccaaatcatcggtggtaaaagacctttccttc
ctggtgaccaatgatcccggctcaggttccgccaaaaatgccaaagcccgcagcctgggt
atccccatcattgacgaggaaggctttttagccatactggctgacccggcgaaggtgaag
gcctacagcccggcaggcggcgtaggcgcactacagggggaacttttttga

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