KEGG   Thalassoglobus polymorphus: Mal48_02460
Entry
Mal48_02460       CDS       T09805                                 
Symbol
metH
Name
(GenBank) Methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
tpol  Thalassoglobus polymorphus
Pathway
tpol00270  Cysteine and methionine metabolism
tpol00450  Selenocompound metabolism
tpol00670  One carbon pool by folate
tpol01100  Metabolic pathways
tpol01110  Biosynthesis of secondary metabolites
tpol01230  Biosynthesis of amino acids
tpol04980  Cobalamin transport and metabolism
tpol04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:tpol00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Mal48_02460 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Mal48_02460 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Mal48_02460 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Mal48_02460 (metH)
   04980 Cobalamin transport and metabolism
    Mal48_02460 (metH)
Enzymes [BR:tpol01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Mal48_02460 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: QDT31016
UniProt: A0A517QHA6
LinkDB
Position
283318..287007
AA seq 1229 aa
MSSTEDKLNEILSERILLLDGSMGALIFSNNPSEEDYRGERFKDHPIDLRNQADILALTQ
PKLIESVHRSYLEAGSDIIETDTFTASIITLEEYQLDHLTYEINKAAAELAKRVAEEFTK
KNPDKPRFVAGSIGPTNRQLSMNADEPGTRPVKFDDMVASYAEQVRGLIDGGADILLPET
SFDTLNMKAALFAIDNVFEEKNVRLPIMVSGTIFDTGTSLTGQTVEAFYTSVSHMPLFSI
GLNCALGPKEMRPHIESLHGLANCRISCYPNAGMPDGMGGFNSNPEEVASNIRYMAENSW
VDIVGGCCGTTPEYIRKIAEAVEDLPSRKIPELSGASNYSGLVRYEITPQSNFSMIGERT
NVTGSRKFARLIKDENYDEALSIAQGQVEGGANIIDVNMDEGLLDSEACMQKFLWLLSDD
AMTVPIMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGEEAFLEQARIIRKYGAAVVVMAF
DEQGQAVDADEKVRICKRAYDLLTTKANFPPEDIIFDPNILTVATGMEEHNNYAVEFFEA
VRRIKEECPGAKTSGGVSNVSFSFRGNNVVREAMNACFLYHAINAGLDMGIVNAGQLEVY
DEIEPKLRDLIEDVLLNRNPEATDRLIEYADEIKEKSSGKKDDTAIAEWRNGTVEERLQY
ALLKGITDHIEADTEEARQKYDRPLNVIQGPLMDGMAVVGQLFGTGKMFLPQVVKSARAM
KKSVAYLEPFMEQEKIDAGLENAPGRGTVVLATVKGDVHDIGKNIVGVVLRCNNFDVIDL
GVMVAADKILETAIEKNADIIGLSGLITPSLEEMIVVAKQMGRDGFTIPLLIGGATTSAK
HTAVRVAPAYSNPVVHVVDASLAVPAVEALIDKDKRAAFIEKNLAQQEKDRVAFGARQER
KLVPYAEAFKRRHQTDWESVEIPTPAFQGTKTIESMDLSNLRDYIDWSPFFSTWELRGKY
PKIFEDEFVGTEAKKLFDEANVLLDKIISEKLFKAKGVYGFWPAVSEGDDIHLFAPEAAN
ADGDPLVTFPMLRQQWERKGQKDFRSLSDYIAPKESGRLDYVGAFAVTAGLGCQELVEKF
DADHDDYNSIMAKALADRLAEAFAEFLHLQARIDWGYGVDEGLSREELIAEKYRGIRPAF
GYPACPDHTPKRTLFDLLDAERITGISLTESYAMWPAASVSGLYFAHPNSRYFSVDRVTK
DQVESYSRRTGMTMAETERWLAPNLGYES
NT seq 3690 nt   +upstreamnt  +downstreamnt
atgtcatcaactgaagacaaactgaacgaaattctttctgaacgaattctattgctcgac
ggatcaatgggagcgttgattttttctaacaaccctagcgaagaagactatcggggggag
cggttcaaagatcatccgatcgatctccggaatcaggccgacatccttgcgctcactcag
cccaagttgattgaaagtgtccatcgcagctaccttgaagctggttcggacattatcgaa
acagacaccttcaccgccagtatcatcactcttgaagagtaccaactcgatcatctgaca
tacgaaattaacaaagcggctgccgaactggcgaagcgagtcgctgaagaattcacgaag
aagaatcctgataaacctcgttttgtcgcgggaagtattgggccgacaaaccgtcagctt
tcgatgaatgcggacgagcccggaacacgtccggtcaagtttgacgacatggtcgcctcg
tatgccgagcaggttcgcggactcattgatggcggggccgacatcctcttgcctgagacg
tcctttgataccttgaacatgaaggcggcgctctttgccatcgataatgtcttcgaagag
aaaaacgtccgacttccaatcatggtttcaggaaccattttcgatactggaacatcttta
accgggcagacagtggaggcgttctatacatccgtttcgcacatgccgctgttcagtatt
gggttgaattgcgcgctcggtcccaaggaaatgcggccgcacatcgagtctttgcatggc
ttggcgaattgcagaatctcttgttatcccaacgctggaatgccggacggaatgggcggg
tttaattccaatccggaagaagtcgcctcaaacattcggtacatggcggagaacagctgg
gtcgatattgtcggggggtgctgcggaacgactcctgagtacattcgcaaaattgcggaa
gcggtcgaggatctgccttcccgtaagattcccgaactctccggggcgtccaattactcg
ggactggtccggtatgaaattacaccacaatccaacttcagcatgattggtgagcgaacc
aacgtgactggttcgcggaagttcgcccgtctcatcaaggacgagaattacgatgaagct
ctttccattgcacaagggcaagtggaaggtggcgcaaacatcatcgacgtcaacatggac
gaagggcttctcgattccgaagcctgtatgcagaagttcttgtggctcctttctgatgat
gcgatgaccgttccgatcatggtcgattcatcaaaatgggaagtcatcgaagctggtctg
aagtgcattcaagggaaggggatcgtcaactcgatcagcctcaaagaaggagaggaagcg
ttcctggagcaagcacggatcatccgaaagtatggtgcagctgttgtcgtcatggccttt
gatgaacaaggtcaggcagtcgatgccgatgagaaagttcgcatttgtaaacgggcttac
gatctcttaaccacgaaggcaaacttcccgccggaagatatcatcttcgacccgaacatt
ctgaccgtcgccaccggaatggaggagcataacaactatgctgtcgaattctttgaagcc
gtcaggcggatcaaggaagaatgccccggtgcgaaaacctctggtggtgtgagtaacgtt
tcgttttcattccgtgggaataacgttgttcgcgaagcgatgaatgcctgcttcctgtac
cacgccatcaatgctgggctggatatggggatcgtcaatgctggtcagttagaggtttac
gatgaaatcgaaccgaagctgcgcgacctcattgaagatgtcttgctgaaccgcaatcca
gaggcgacagaccggctcatcgagtacgctgatgaaattaaggagaaaagctccgggaag
aaagacgataccgcaatcgctgagtggcggaacggaaccgtcgaagagcggttgcagtat
gcactgctcaagggaatcaccgatcacatcgaagctgacaccgaagaagctcggcagaaa
tacgatcgcccgctgaatgtgattcaggggccgttgatggatggaatggctgtggtcggg
caactcttcggaacaggaaaaatgttcctgccgcaggttgtgaagtcggctcgtgcgatg
aagaaatcggtggcctatcttgaaccgttcatggagcaggaaaaaattgacgctggcctc
gagaatgctccggggcgaggaacggttgtccttgcgactgtgaagggagatgttcacgat
atcggtaagaatatcgtgggggtcgtcttgcgctgcaataactttgatgtcatcgatctt
ggagtgatggttgcagcggataaaattctcgagactgctattgaaaagaatgcagatatt
atcggcctctctggcctgatcactccttcgctggaagaaatgatcgtcgtggcgaagcag
atgggacgggacggttttacgatcccgctactgatcggcggagcaacgacatccgcaaag
cacacggctgtccgggtggcccctgcgtattccaacccagtggtgcatgttgttgatgcc
tcacttgctgtcccagcggtcgaagccctgatcgacaaggataaacgagctgcattcatt
gaaaagaatcttgcgcagcaagaaaaggatcgcgttgccttcggcgcccggcaggaacga
aaactcgtcccgtacgcagaggctttcaagcgacgacatcagactgattgggagtcggtg
gagattcccacgcctgcattccaggggacgaaaactatcgaatcgatggacctttcgaat
ctccgggactatatcgactggtcaccgttcttcagtacgtgggaattgcgaggaaagtat
ccgaagatctttgaagatgagtttgtcgggactgaagcgaagaagctctttgatgaagca
aacgtgctgttagacaaaattatttcggagaaactcttcaaagcgaagggcgtgtacgga
ttttggcctgccgtcagcgaaggggatgatattcatctgttcgcaccagaagcagccaat
gccgatggcgatccacttgtcaccttcccgatgcttcgccagcaatgggaacgaaaaggg
caaaaagacttccgctccctttccgactatatcgctccgaaagagtctggtcgactggac
tacgtcggagccttcgcggtgacggccggtctcggttgtcaggaactcgtcgagaagttt
gatgccgatcacgatgactacaattcaatcatggcgaaagccttggcggatcgtcttgcg
gaagcgttcgcggaatttctccatcttcaggcccgaattgactggggatatggagttgat
gaagggctcagccgagaagagctgattgcggagaaataccgcggaattcgtcccgcattt
ggatatcccgcctgtccggatcatacgccgaaaagaacccttttcgatctcctcgacgcc
gaaagaatcacaggcatttccctgacggaatcgtatgccatgtggccggcagcttcggtt
tctggactgtactttgctcatccgaatagccgatacttcagtgtcgaccgggtgactaaa
gaccaggttgaaagctattccaggcgtaccgggatgacaatggccgaaactgaacgctgg
ctcgccccgaatttgggctatgagagttga

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