Thalassoglobus polymorphus: Mal48_02460
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Entry
Mal48_02460 CDS
T09805
Symbol
metH
Name
(GenBank) Methionine synthase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
tpol
Thalassoglobus polymorphus
Pathway
tpol00270
Cysteine and methionine metabolism
tpol00450
Selenocompound metabolism
tpol00670
One carbon pool by folate
tpol01100
Metabolic pathways
tpol01110
Biosynthesis of secondary metabolites
tpol01230
Biosynthesis of amino acids
tpol04980
Cobalamin transport and metabolism
tpol04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
tpol00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
Mal48_02460 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
Mal48_02460 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
Mal48_02460 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
Mal48_02460 (metH)
04980 Cobalamin transport and metabolism
Mal48_02460 (metH)
Enzymes [BR:
tpol01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
Mal48_02460 (metH)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Met_synt_B12
S-methyl_trans
Pterin_bind
B12-binding_2
B12-binding
Motif
Other DBs
NCBI-ProteinID:
QDT31016
UniProt:
A0A517QHA6
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Position
283318..287007
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AA seq
1229 aa
AA seq
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MSSTEDKLNEILSERILLLDGSMGALIFSNNPSEEDYRGERFKDHPIDLRNQADILALTQ
PKLIESVHRSYLEAGSDIIETDTFTASIITLEEYQLDHLTYEINKAAAELAKRVAEEFTK
KNPDKPRFVAGSIGPTNRQLSMNADEPGTRPVKFDDMVASYAEQVRGLIDGGADILLPET
SFDTLNMKAALFAIDNVFEEKNVRLPIMVSGTIFDTGTSLTGQTVEAFYTSVSHMPLFSI
GLNCALGPKEMRPHIESLHGLANCRISCYPNAGMPDGMGGFNSNPEEVASNIRYMAENSW
VDIVGGCCGTTPEYIRKIAEAVEDLPSRKIPELSGASNYSGLVRYEITPQSNFSMIGERT
NVTGSRKFARLIKDENYDEALSIAQGQVEGGANIIDVNMDEGLLDSEACMQKFLWLLSDD
AMTVPIMVDSSKWEVIEAGLKCIQGKGIVNSISLKEGEEAFLEQARIIRKYGAAVVVMAF
DEQGQAVDADEKVRICKRAYDLLTTKANFPPEDIIFDPNILTVATGMEEHNNYAVEFFEA
VRRIKEECPGAKTSGGVSNVSFSFRGNNVVREAMNACFLYHAINAGLDMGIVNAGQLEVY
DEIEPKLRDLIEDVLLNRNPEATDRLIEYADEIKEKSSGKKDDTAIAEWRNGTVEERLQY
ALLKGITDHIEADTEEARQKYDRPLNVIQGPLMDGMAVVGQLFGTGKMFLPQVVKSARAM
KKSVAYLEPFMEQEKIDAGLENAPGRGTVVLATVKGDVHDIGKNIVGVVLRCNNFDVIDL
GVMVAADKILETAIEKNADIIGLSGLITPSLEEMIVVAKQMGRDGFTIPLLIGGATTSAK
HTAVRVAPAYSNPVVHVVDASLAVPAVEALIDKDKRAAFIEKNLAQQEKDRVAFGARQER
KLVPYAEAFKRRHQTDWESVEIPTPAFQGTKTIESMDLSNLRDYIDWSPFFSTWELRGKY
PKIFEDEFVGTEAKKLFDEANVLLDKIISEKLFKAKGVYGFWPAVSEGDDIHLFAPEAAN
ADGDPLVTFPMLRQQWERKGQKDFRSLSDYIAPKESGRLDYVGAFAVTAGLGCQELVEKF
DADHDDYNSIMAKALADRLAEAFAEFLHLQARIDWGYGVDEGLSREELIAEKYRGIRPAF
GYPACPDHTPKRTLFDLLDAERITGISLTESYAMWPAASVSGLYFAHPNSRYFSVDRVTK
DQVESYSRRTGMTMAETERWLAPNLGYES
NT seq
3690 nt
NT seq
+upstream
nt +downstream
nt
atgtcatcaactgaagacaaactgaacgaaattctttctgaacgaattctattgctcgac
ggatcaatgggagcgttgattttttctaacaaccctagcgaagaagactatcggggggag
cggttcaaagatcatccgatcgatctccggaatcaggccgacatccttgcgctcactcag
cccaagttgattgaaagtgtccatcgcagctaccttgaagctggttcggacattatcgaa
acagacaccttcaccgccagtatcatcactcttgaagagtaccaactcgatcatctgaca
tacgaaattaacaaagcggctgccgaactggcgaagcgagtcgctgaagaattcacgaag
aagaatcctgataaacctcgttttgtcgcgggaagtattgggccgacaaaccgtcagctt
tcgatgaatgcggacgagcccggaacacgtccggtcaagtttgacgacatggtcgcctcg
tatgccgagcaggttcgcggactcattgatggcggggccgacatcctcttgcctgagacg
tcctttgataccttgaacatgaaggcggcgctctttgccatcgataatgtcttcgaagag
aaaaacgtccgacttccaatcatggtttcaggaaccattttcgatactggaacatcttta
accgggcagacagtggaggcgttctatacatccgtttcgcacatgccgctgttcagtatt
gggttgaattgcgcgctcggtcccaaggaaatgcggccgcacatcgagtctttgcatggc
ttggcgaattgcagaatctcttgttatcccaacgctggaatgccggacggaatgggcggg
tttaattccaatccggaagaagtcgcctcaaacattcggtacatggcggagaacagctgg
gtcgatattgtcggggggtgctgcggaacgactcctgagtacattcgcaaaattgcggaa
gcggtcgaggatctgccttcccgtaagattcccgaactctccggggcgtccaattactcg
ggactggtccggtatgaaattacaccacaatccaacttcagcatgattggtgagcgaacc
aacgtgactggttcgcggaagttcgcccgtctcatcaaggacgagaattacgatgaagct
ctttccattgcacaagggcaagtggaaggtggcgcaaacatcatcgacgtcaacatggac
gaagggcttctcgattccgaagcctgtatgcagaagttcttgtggctcctttctgatgat
gcgatgaccgttccgatcatggtcgattcatcaaaatgggaagtcatcgaagctggtctg
aagtgcattcaagggaaggggatcgtcaactcgatcagcctcaaagaaggagaggaagcg
ttcctggagcaagcacggatcatccgaaagtatggtgcagctgttgtcgtcatggccttt
gatgaacaaggtcaggcagtcgatgccgatgagaaagttcgcatttgtaaacgggcttac
gatctcttaaccacgaaggcaaacttcccgccggaagatatcatcttcgacccgaacatt
ctgaccgtcgccaccggaatggaggagcataacaactatgctgtcgaattctttgaagcc
gtcaggcggatcaaggaagaatgccccggtgcgaaaacctctggtggtgtgagtaacgtt
tcgttttcattccgtgggaataacgttgttcgcgaagcgatgaatgcctgcttcctgtac
cacgccatcaatgctgggctggatatggggatcgtcaatgctggtcagttagaggtttac
gatgaaatcgaaccgaagctgcgcgacctcattgaagatgtcttgctgaaccgcaatcca
gaggcgacagaccggctcatcgagtacgctgatgaaattaaggagaaaagctccgggaag
aaagacgataccgcaatcgctgagtggcggaacggaaccgtcgaagagcggttgcagtat
gcactgctcaagggaatcaccgatcacatcgaagctgacaccgaagaagctcggcagaaa
tacgatcgcccgctgaatgtgattcaggggccgttgatggatggaatggctgtggtcggg
caactcttcggaacaggaaaaatgttcctgccgcaggttgtgaagtcggctcgtgcgatg
aagaaatcggtggcctatcttgaaccgttcatggagcaggaaaaaattgacgctggcctc
gagaatgctccggggcgaggaacggttgtccttgcgactgtgaagggagatgttcacgat
atcggtaagaatatcgtgggggtcgtcttgcgctgcaataactttgatgtcatcgatctt
ggagtgatggttgcagcggataaaattctcgagactgctattgaaaagaatgcagatatt
atcggcctctctggcctgatcactccttcgctggaagaaatgatcgtcgtggcgaagcag
atgggacgggacggttttacgatcccgctactgatcggcggagcaacgacatccgcaaag
cacacggctgtccgggtggcccctgcgtattccaacccagtggtgcatgttgttgatgcc
tcacttgctgtcccagcggtcgaagccctgatcgacaaggataaacgagctgcattcatt
gaaaagaatcttgcgcagcaagaaaaggatcgcgttgccttcggcgcccggcaggaacga
aaactcgtcccgtacgcagaggctttcaagcgacgacatcagactgattgggagtcggtg
gagattcccacgcctgcattccaggggacgaaaactatcgaatcgatggacctttcgaat
ctccgggactatatcgactggtcaccgttcttcagtacgtgggaattgcgaggaaagtat
ccgaagatctttgaagatgagtttgtcgggactgaagcgaagaagctctttgatgaagca
aacgtgctgttagacaaaattatttcggagaaactcttcaaagcgaagggcgtgtacgga
ttttggcctgccgtcagcgaaggggatgatattcatctgttcgcaccagaagcagccaat
gccgatggcgatccacttgtcaccttcccgatgcttcgccagcaatgggaacgaaaaggg
caaaaagacttccgctccctttccgactatatcgctccgaaagagtctggtcgactggac
tacgtcggagccttcgcggtgacggccggtctcggttgtcaggaactcgtcgagaagttt
gatgccgatcacgatgactacaattcaatcatggcgaaagccttggcggatcgtcttgcg
gaagcgttcgcggaatttctccatcttcaggcccgaattgactggggatatggagttgat
gaagggctcagccgagaagagctgattgcggagaaataccgcggaattcgtcccgcattt
ggatatcccgcctgtccggatcatacgccgaaaagaacccttttcgatctcctcgacgcc
gaaagaatcacaggcatttccctgacggaatcgtatgccatgtggccggcagcttcggtt
tctggactgtactttgctcatccgaatagccgatacttcagtgtcgaccgggtgactaaa
gaccaggttgaaagctattccaggcgtaccgggatgacaatggccgaaactgaacgctgg
ctcgccccgaatttgggctatgagagttga
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