Tsukamurella paurometabola: Tpau_2722
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Entry
Tpau_2722 CDS
T01228
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
tpr
Tsukamurella paurometabola
Pathway
tpr00010
Glycolysis / Gluconeogenesis
tpr00020
Citrate cycle (TCA cycle)
tpr00620
Pyruvate metabolism
tpr00785
Lipoic acid metabolism
tpr01100
Metabolic pathways
tpr01110
Biosynthesis of secondary metabolites
tpr01120
Microbial metabolism in diverse environments
tpr01200
Carbon metabolism
tpr01210
2-Oxocarboxylic acid metabolism
Module
tpr_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tpr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Tpau_2722
00020 Citrate cycle (TCA cycle)
Tpau_2722
00620 Pyruvate metabolism
Tpau_2722
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Tpau_2722
Enzymes [BR:
tpr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Tpau_2722
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
ADG79320
UniProt:
D5USP9
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All DBs
Position
2825209..2828022
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AA seq
937 aa
AA seq
DB search
MTDPTASTPAPASSGQGPAPSNDGRPDRVRVIREGVASYLPDIDPEETGEWLESFDDLIA
THGPARARYLMLRLLERASENRVSIPSLTSTDYVNTIPTDLEPWFPGDEEIERRYRAWIR
WNAAIMVHRAQRPGVGVGGHISTYASSAALYEVGFNHFFRGKEHPGGGDQVFIQGHASPG
IYARAFLEGRIPAERMDGFRQEKSHEDKGKGLPSYPHPRLLSNFWEFPTVSMGLGPMNAI
MQARFNHYLHDRGIKDTSDQHVWAFLGDGEMDEPESRGQIQIAATEGLDNLTFVVNCNLQ
RLDGPVRGNGKIIQELESFFRGAGWNVIKVIWGREWDELLHKDRDGALVNIMNTTPDGDY
QTFKANDGAFVREHFFGRDPRTKELVKDMTDEQIWGLRRGGHDYRKVYAAYKSAMEHKGQ
PTVILAHTIKGFGLGHNFEGRNATHQMKKLTLDDLKQFRDELRIPITDEELEKDPYLPPY
YNPGPESKEIQYMLERRKTLGGFLPARRTEAQALTTPDITALDVMRKGSGKQQVATTMAV
VRIFKELLRDPEVGHRIVPIIPDEARTFGMDSWFPSLKIYNRLGQTYTSVDAQLMLAYKE
NPQGVILHEGINEAGSTASFTAVGTSYATHDVPMIPLYIFYSMFGFQRTGDGLWAAADQM
ARGFVLGATAGRTTLTGEGLQHADGHSHVLASTNPAVVAYDPAFGYELAHIVIDGLRRMY
GENPENIYYYVTVYNEPIHQPAEPENLDVEGLLKGMYLYRPASAGHARKASILASGVTMP
DALVAQELLAQEWGVDASVYSVTSWVELSRDGIEAEKAALRDPAAPARTPHVTKVLADAQ
GPTVAASDFMRGTQDLIRAWVPGTYLTLGTDGFGFSDTRPAARRYFNVDAQSIVVGVLLA
LARDGELDFSVAAEAAKRYRIDDVLAAPKQTSDPGVA
NT seq
2814 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgacccgaccgcctccaccccggcacccgcatcatcgggacagggacccgcaccg
tcgaacgacggtcgcccggaccgggtccgcgtgatccgcgagggggtggcgtcctacctt
ccggacatcgacccggaggagaccggcgaatggctcgagtcgttcgacgacctgatagcc
acccacgggccggcccgcgcccgctacctgatgctgcgactcttggagcgcgccagcgag
aaccgggtgtcgatcccgtcgctcacgtccacggattacgtgaacaccatccccaccgat
ctcgagccgtggttccccggcgacgaggagatcgagcgccggtaccgcgcctggatccga
tggaacgccgcgatcatggtccaccgcgcccagcgccccggcgtgggcgtcggcgggcac
atctccacctacgccagctcggcggcgctgtacgaggtgggcttcaaccacttcttccgg
ggcaaggagcacccgggcggcggcgaccaggtgttcattcagggtcacgcctcccccggc
atctacgcccgcgcgttcctcgaaggccgtatcccggctgagcggatggacggcttccgc
caggagaagtcgcacgaggacaagggcaagggccttccctcgtacccgcacccccgtctg
ctgtcgaacttctgggagttcccgacggtgtcgatgggtctgggcccgatgaacgcgatc
atgcaggcgcgcttcaatcattacctgcacgaccgcggcatcaaggacacgtcggatcag
cacgtctgggcgttcctgggcgacggtgagatggacgaacccgaatcgcgcggccagatt
cagatcgccgcgaccgagggcctcgacaacctgaccttcgtggtcaactgcaacctgcag
cgactcgacgggccggtgcggggcaacggcaagatcatccaggagttggagtccttcttc
cgcggtgccggctggaacgtgatcaaggtgatctggggtcgcgagtgggacgagctgctg
cacaaggaccgcgacggcgcgctggtgaacatcatgaacaccacgccggacggcgactac
cagaccttcaaggcgaacgacggcgccttcgtccgtgagcacttcttcggccgcgatccg
cggaccaaggaactggtcaaggacatgaccgacgagcagatctggggcctgcggcgtggc
ggtcacgactaccgcaaggtgtacgccgcgtacaagtcggcgatggaacacaagggccag
cccaccgtgatcctggcgcacaccatcaagggcttcggcctgggccacaacttcgagggc
cgtaacgccacgcaccagatgaagaagctcacgctcgacgatctcaagcagttccgcgac
gagctccgcatcccgatcaccgacgaggagctggagaaggatccctaccttcccccgtac
tacaaccccggaccggagtcgaaggagatccagtacatgctggagcgtcgcaagacgctc
ggcggcttcctgcccgcccgccgtaccgaggcgcaggcactcacgacgccggacatcacc
gcgctcgatgtgatgcgcaagggctccggtaagcaacaggtggccaccacaatggcggtg
gtccggatcttcaaggagctgctgcgcgaccccgaggtcgggcaccgcatcgtcccgatc
attcccgacgaggcccgcaccttcggcatggacagctggttcccgtcgctgaagatctac
aaccgcctgggacagacctacacatcggtcgatgcgcagctgatgctggcctacaaggag
aacccgcagggcgtgatcctgcacgagggcatcaacgaggccggatccacggcgtcgttc
accgccgtcggcacctcctacgccacgcacgacgtgcccatgatcccgctgtacatcttc
tattcgatgttcggtttccagcgcacgggcgacggcctgtgggccgcggccgatcagatg
gcccgcgggttcgtgctcggcgccaccgctgggcgcaccacgctgaccggtgagggactg
cagcacgccgacggtcacagtcacgtcctggcttcgaccaatcccgccgtggtcgcctac
gacccggccttcggttacgagctcgcgcacatcgtcatcgacggcctgcgccggatgtac
ggcgagaacccggagaacatctactactacgtcaccgtgtacaacgagcccatccatcag
ccggccgagccggagaacctcgacgtcgagggtctgctcaaggggatgtacctctatcgt
ccggcatcggcggggcacgcgaggaaggccagcatcctcgcgtccggtgtgacgatgccc
gatgccctggtcgcgcaggaactgctcgcacaggaatggggcgtggatgcatcggtctac
tcggtcacgagctgggtggagctgtcccgggacggcatcgaggcggagaaggcggcgctg
cgcgatccggcggcgccggctcgcacgccgcacgtgaccaaggtgctcgccgatgcccag
ggcccgacggtggcggcatcggacttcatgcgcggcacccaggacctgatccgtgcgtgg
gttcccggcacctatctcaccctgggcaccgacggcttcggcttctccgacacccggccg
gcggcgcgtcgctacttcaacgtggacgcgcagtcgatcgtcgtaggggttctgctggca
ctcgcccgggacggggagctcgacttctccgtcgccgcggaggccgcgaagcggtaccgg
atcgacgacgtgctcgccgcgccgaagcagacgtcggaccccggcgtagcctag
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