Trueperella pyogenes TP8: X956_08065
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Entry
X956_08065 CDS
T03579
Symbol
kgd
Name
(GenBank) alpha-ketoglutarate decarboxylase
KO
K01616
multifunctional 2-oxoglutarate metabolism enzyme [EC:
2.2.1.5
4.1.1.71
1.2.4.2
2.3.1.61
]
Organism
tpyo
Trueperella pyogenes TP8
Pathway
tpyo00020
Citrate cycle (TCA cycle)
tpyo00630
Glyoxylate and dicarboxylate metabolism
tpyo00785
Lipoic acid metabolism
tpyo01100
Metabolic pathways
tpyo01110
Biosynthesis of secondary metabolites
tpyo01120
Microbial metabolism in diverse environments
tpyo01200
Carbon metabolism
tpyo01210
2-Oxocarboxylic acid metabolism
Module
tpyo_M00009
Citrate cycle (TCA cycle, Krebs cycle)
tpyo_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
tpyo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
X956_08065 (kgd)
00630 Glyoxylate and dicarboxylate metabolism
X956_08065 (kgd)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
X956_08065 (kgd)
Enzymes [BR:
tpyo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.2 oxoglutarate dehydrogenase (succinyl-transferring)
X956_08065 (kgd)
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.5 2-hydroxy-3-oxoadipate synthase
X956_08065 (kgd)
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.61 dihydrolipoyllysine-residue succinyltransferase
X956_08065 (kgd)
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.71 2-oxoglutarate decarboxylase
X956_08065 (kgd)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
E1_dh
2-oxoacid_dh
Transket_pyr
OxoGdeHyase_C
2-oxogl_dehyd_N
Glyco_hydro_38N
Motif
Other DBs
NCBI-ProteinID:
AJC69975
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All DBs
Position
1723510..1727265
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AA seq
1251 aa
AA seq
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MQRKARQTVSSTNDDFGANQGFIEELYAAYLGNKDGVGPQWAEMFRAWEAEGRTPRLGKD
AEHIGETAEKKEVTATQRAVHSQADRASTPSTNVTRSDLPPQPRAAAAPAITPYAKSYTL
RPADAEQDMDPKAKDVTPLKGGDRGLAKNMDASLSIPTATSLRALPARVMFDNRAVINRY
LAATRGGKISFTHLIAYAMVESLAEMPEMNVAYALENGKPALVAPKHVNLGIAIDVVKPD
GARTLVVPSIKAAETMTFSEFVSAYEDLVERGRQNKLSIEDYQGTTATLTNPGGLGTTES
VPRLMVGQGLIVGVGSMTYPPEFQGTAEETIARLGISKVVNIGSTYDHRVIQGATSGRFL
RLMETKLLGLDGFYERVYVSLRVPYTPITWEKDVEYDAERELGKPARIAELIHAYRSRGH
LIADTDPLSFHLRRHPDLEISSYGLSLWDLDRSFPTGGFAGTSHLTLRDILTNLRDAYCR
TVGIEYMHIQDPVQRAWFQERLECKPKSTTAQQRIRILEKLNQAEAFEVFLQTKYVGQKR
FSLEGGESLIPALDAILGGAANDGLHQVAIGMAHRGRLNVLTNIAGKSFGQVFSEFDGVM
DPKKPGSGDVKYHLGTEGTYTAANGDQVGVYLAANPSHLEAADGVLEGVARAMQDQLDLD
DDGAAVVPLLIHGDAAFSGQGVVTEVLNLSQLPAYRTGGTVHIIVNNQIGFTTAPSNSRS
SRYTTDIAKGLQLPIFHVNGDDPEAVCRMARMAYDYRMEFRKDVILDIICYRKRGHNEGD
DPSMTQPIMYSLVDEKRSTRQLYREALLGRGDISDEEAAKVEQDFHTLLEQAFQKVREVE
NKAETAQGKAADSLGVPSSQQEDAGTMVGWATAVAPEVLQRIGKAHTTPPEGFTVHKKVM
SLFHKRNAMTHEGHIDWGFGELLAFGSLLIEGVPVRMSGQDSRRGTFTQRHAVVHDSRTG
AEWTPLMGLTEDQARFKIYDSALSEYSIMAFEYGYSVQRPDALVLWEAQFGDFANGAQTV
VDEFISSAEQKWHQSSSIVLLLPHGYEGQGPDHSSARIERYLQLCAEENMVVVQPTTPAN
YFHMLREQAYRRPRKPMIVFSPKQLLRRKGVESALAEFTSGTVRKVIGETRQLGAVDRVL
LCTGRIYYDLLEQREKNDDERTAIIRVEQLYPNPVDEVRAELEKYPGAEVFWVQDEPANQ
GAWAHFALDMFPQLDRGIARISRPAAASTAAGMASLHRTETAELMRQAFER
NT seq
3756 nt
NT seq
+upstream
nt +downstream
nt
atccaacgaaaagcgaggcagacagtgtcgtcaaccaacgatgattttggagcgaaccag
ggcttcattgaggagctctacgcggcctacctaggcaacaaggatggagtgggtccacag
tgggcggagatgttccgcgcctgggaagcagaagggcgcacgccgcgcctcggcaaagat
gccgaacacatcggggagacggcagagaagaaggaagtgacagccacgcagcgcgctgtg
cattcccaggccgaccgcgcttccacaccctcgacgaatgtcacgcgctccgacctaccc
ccacagccgcgtgcagccgccgcgcccgccatcacaccctacgccaagtcctacacgctg
cgcccggccgacgccgagcaggacatggatcccaaggccaaagacgtcacgcccctcaag
ggcggcgaccgtgggctagcaaaaaacatggacgcctcgctgtccatccccaccgccacc
tcgctgcgcgcccttcccgcacgcgtcatgttcgacaaccgggccgtcatcaaccgctac
ctggcggccacgcgcggcggaaagatctccttcacccacctcatcgcctacgccatggtc
gaatcgctcgccgaaatgccggagatgaacgtcgcctacgcgctggaaaacggcaaaccc
gccctcgttgcgcccaaacatgtcaacctcggcatcgcgatcgacgtcgtcaagcccgac
ggcgcccgcacgctcgtcgtgccctcgatcaaggcagccgaaacgatgacgttctccgag
ttcgtctctgcctacgaagatctcgtcgagcgcgggcgccaaaataagctcagtatcgag
gactaccaaggcactaccgccacactcaccaatccagggggcctcggtacgaccgagtcc
gtgccacgcctgatggtaggccaggggctcattgtcggcgtcggttcgatgacctacccg
cccgagttccagggcaccgccgaggagacgatcgcccgcctgggcatatcgaaagtggtc
aacatcggctccacctacgatcaccgcgtcattcaaggggcgacctccgggcgcttcctg
cgcctcatggagaccaagctcctcgggctcgatggcttctatgagcgcgtctatgtctca
ctgcgcgtcccctacacgcccatcacgtgggaaaaggacgtcgaatacgacgccgaacgc
gagctcggcaagcccgcgcgcatcgccgagctcatccacgcttatcgttcccgcgggcac
ctcatcgcggacaccgacccgctttctttccacctacgccgccaccccgacctcgagatc
agctcctacggcctgagcctgtgggatctagatcggtccttccccaccggtggcttcgcc
ggcaccagccacctgaccctgcgcgacatcctcaccaaccttcgcgatgcctactgccgc
acggtaggcatcgaatacatgcatatccaagatcctgtgcagcgcgcatggttccaggaa
cgtcttgaatgcaaaccgaaatccacgacggcgcaacagcgcatccgtatcctcgaaaag
ctcaaccaggccgaagccttcgaagtttttctccagacgaaatacgtcggccaaaagcgc
ttctccttggagggtggcgagtcgctcatccctgcgctcgatgcgatcctcggtggcgcg
gccaatgacgggctgcaccaggtcgccatcggtatggcacaccggggacgcctcaacgtg
ctcaccaacattgctggcaagtcctttggccaggtgttttccgaatttgacggcgtcatg
gaccccaaaaagccgggatcgggtgatgttaagtatcacctcggcacggagggcacttac
actgcggccaacggcgaccaggtgggcgtctatctcgcggccaacccctcccacctcgag
gcggccgacggggtcctcgaaggcgtcgcccgcgccatgcaagaccagctcgacctcgac
gacgacggcgccgcggtcgtccccctgcttatccatggcgatgcggccttttccggtcag
ggcgtcgtcaccgaggtgttgaatctctcccagctgcccgcctaccgcaccggcggcacg
gttcacatcatcgtcaacaaccaaatcggcttcaccacagccccatcgaattcccgatcc
tcgcgctacaccactgacatcgccaagggtctgcaactgccgatattccacgtcaacggt
gacgatcccgaggcggtgtgccgcatggcacgcatggcctacgactaccgcatggaattt
aggaaagacgtcatcctcgatatcatctgctaccgcaagcgtggccataacgaaggcgac
gacccgtcgatgacgcaacccatcatgtactcgctcgtcgatgagaagcgctccacacgc
cagctctaccgggaggctttgctcggccgcggtgacatctccgacgaagaagcggccaag
gtcgaacaggactttcacaccctgctcgaacaggccttccaaaaagtccgcgaagtggaa
aacaaggctgagaccgcgcagggcaaggccgccgatagcctcggcgtgccctcctcccag
caagaagacgccggcacgatggtgggctgggccaccgccgtcgcccccgaggtgcttcaa
cgcattggtaaagcccataccaccccgccagagggcttcaccgtccataagaaagtcatg
tcgctctttcacaagcgcaacgccatgactcacgaaggccacatcgactggggctttggc
gaactactcgccttcggctctctcctcatcgaaggcgtaccggttcgcatgtccggccaa
gactcccgccgcggcacgtttacccagcgccacgccgtcgtacacgactcccgcaccggc
gcagagtggacgccgctcatgggcctgaccgaggatcaggcgcgctttaagatatacgac
tcggcgctgtcggagtactcgatcatggccttcgagtacggctattcggttcagcgccca
gacgcgctcgtcctgtgggaagcacagttcggagattttgccaacggcgcccaaaccgtc
gtcgacgaattcatctcgtctgccgaacaaaagtggcaccaatcttcgtcgatcgtgctg
ctcttgccgcacggctacgaaggccaaggccccgatcactcctccgcccgcattgagcgc
tacttgcagctgtgtgcagaggagaacatggtcgtcgtccagccgaccaccccggcgaac
tacttccacatgttgcgtgagcaagcctaccgacgcccgcgcaagccgatgatcgtcttc
tcgcccaagcagctgctgcgccgcaaaggagtcgagtccgccctcgcggaatttacctct
ggcacggtgcgcaaggtgatcggggagacgcgccaactcggcgccgtcgaccgcgtgctc
ctgtgcaccggcagaatctactacgacctgcttgagcagcgcgaaaagaacgacgacgaa
cggacggccatcatccgcgtcgaacagctttacccaaatcccgtagacgaggtgcgggca
gagctggagaagtatccaggtgccgaggtcttctgggttcaggacgagccagccaatcaa
ggtgcatgggcgcactttgctctcgacatgttcccacagctcgatcgcggcatcgcgcgc
atatcgcgccccgccgcggcgtcgacggcggcaggtatggctagcctccatcgcaccgaa
acggccgagttgatgcgccaagcctttgaacggtga
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