Trichomycterus rosablanca: 134323829
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Entry
134323829 CDS
T09921
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
trn
Trichomycterus rosablanca
Pathway
trn00140
Steroid hormone biosynthesis
trn01100
Metabolic pathways
Module
trn_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
trn_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
trn_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
trn00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
134323829 (hsd3b1)
Enzymes [BR:
trn01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
134323829 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
134323829 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
NmrA
KR
RmlD_sub_bind
adh_short
Motif
Other DBs
NCBI-GeneID:
134323829
NCBI-ProteinID:
XP_062861437
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Position
12:13035648..13042286
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AA seq
374 aa
AA seq
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MPLSGEVCVVTGACGFLGGKLVRLLLEEEKLTEIRLLDKNIRPELIQSLEGCRGEAKLSV
FEGDIRDSELLKSLCRGVSLVFHTASLIDVTGAIAYSKLHEVNVKGTQLLLEACMQENVA
SFIYTSSIEVAGPNHHGDPIINGNEDTEYLACLKFPYSQSKKEAERLCLNAQGEMLQNGG
RLATCALRPMYIYGEGCRFTLGHMRDGIRNGDVLLRTSKPEAKVNPVYVGNVALAHLQAA
RALRDPEKRSVVGGNFYYISDDTPPVSYSDFNHAVLSPLGFSIQERPSLPFSILYIICFL
MEVLKAVLYPILRFTPPLNRQLLIMLNTPFTFSYQKAKQDLGYAPRYDWAEARKRTTDWL
ASVLPRERERINAK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgcctctgtcaggagaagtgtgtgtggtaactggagcatgtggctttcttggtggaaag
ctggttaggctgttactggaggaagaaaaactcacagagattcgactcctagacaaaaac
attcgacctgaactcattcagtctctggaaggttgccggggtgaggcaaaactgagtgtg
tttgaaggggacatcagggacagtgagctgttaaagagtctgtgtagaggagtgtccctt
gtttttcacactgcctcacttattgatgtcacaggagctattgcctatagcaaactgcat
gaagtgaacgtcaaaggcactcagctgctcctagaagcgtgtatgcaggagaatgttgct
tccttcatatacaccagcagcattgaagttgcaggtccaaatcatcacggtgaccctatc
atcaatggtaatgaggacacagagtacctcgcctgcttaaagtttccctacagccaaagc
aaaaaagaagctgaacggctttgccttaacgcccagggtgaaatgcttcaaaatggtggc
cggctggctacctgtgctctgaggcccatgtatatctatggagagggttgccgatttacc
ttaggacatatgagggatggaattagaaatggtgatgtgttgctgcggacttcaaaaccc
gaggctaaagtcaatccagtgtacgtgggaaatgtggctctcgcacatttgcaagccgct
cgagcgctgagagacccagagaagagatctgtggtcggtggaaacttttactacatctca
gatgacacgccacctgtcagctattctgactttaatcatgccgttctgtcaccgctgggc
tttagcatacaggagaggcctagtttacctttctctatcctctacatcatttgctttctc
atggaagtgctcaaagctgtgctttatcccattctccgcttcacaccaccactaaacagg
cagcttctaatcatgcttaacacaccctttactttttcatatcaaaaggccaaacaagat
ttgggatatgctcctcgttatgactgggcagaggcacgcaaaagaactactgattggctg
gcgtctgtcttacctagagaaagagaaagaattaatgcaaaataa
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