Triplophysa rosa: 130555852
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Entry
130555852 CDS
T09216
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
tros
Triplophysa rosa
Pathway
tros00140
Steroid hormone biosynthesis
tros01100
Metabolic pathways
Module
tros_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
tros_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
tros_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
tros00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
130555852 (hsd3b1)
Enzymes [BR:
tros01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
130555852 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
130555852 (hsd3b1)
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Gene cluster
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
Polysacc_synt_2
GDP_Man_Dehyd
NAD_binding_10
KR
NmrA
RmlD_sub_bind
adh_short
Motif
Other DBs
NCBI-GeneID:
130555852
NCBI-ProteinID:
XP_057192354
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Position
LG6:complement(16293020..16297477)
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AA seq
374 aa
AA seq
DB search
MSLAGEVCVVTGACGFLGEKLVRLLLEEEKLAEIRLLDRNMRSELIQSLDDCRGDTKLSV
FEGDIRECELLRRACRGAALVFHTASLIDVTGAIEYSELYGVNVKGTQLLIETCIQENMA
SFIYTSSIEVAGPNPCGDPIINGNEDTPYTSSLKFNYSKTKDEAEQICLQANGEILRNGG
QLATCALRPMYIFGEGCRFTLGHMRDGIRNGNLLLRTSSREAKVNPVYVGNVALAHLQAA
RALRDHQKRAVMGGNFYYISDDTPPVSYSDFNYAVLSTLGFGMQERHILPLPLLYLLSYF
MEFLHIVLHPFLRFTPPINRQLLTMLNTPFSFSYQKAHRDFGYSPRYDWEEARRRTTDWL
ASVLPIERQRLNSK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtctctggcaggagaagtatgtgtggtgacaggagcgtgtgggtttctgggagaaaag
ctggtcagactgttgctggaggaggaaaagcttgctgaaatccgactgctggacagaaac
atgcgatctgagctaatacagtctcttgacgattgcagaggagatactaaactgagtgtg
tttgagggagacatcagggagtgtgagctgttgagaagagcctgcaggggagcagcactt
gtttttcacactgcatctctcatcgatgtcactggagcaatcgagtacagtgaattatat
ggtgtcaatgttaaaggaacacaactactgattgagacatgcatacaggagaatatggcc
tccttcatttacacaagcagcattgaggttgctggtccaaatccttgcggtgatccaatc
atcaacggcaatgaggacacgccttacacctcaagtcttaagtttaactacagcaaaacc
aaagatgaggctgaacagatttgccttcaggctaatggagagattctgcgcaacggaggc
cagctggctacctgtgcattaagacccatgtacatcttcggagagggttgtcgttttaca
ttaggtcacatgagagatggaatccgtaatggaaacttgctgcttagaacctcaagtcgt
gaggcaaaagtgaatcctgtatatgtgggaaatgtagctcttgcacatctacaagctgcg
cgagccctcagagatcaccaaaagagagcagtgatgggtggaaacttctactacatctca
gatgacaccccacctgtcagctactcggactttaactacgctgttctttcaactttaggc
tttgggatgcaagagagacatattttgcccctcccccttctctatctgctgtcatacttc
atggaattcctgcatattgtgctccacccctttctgagatttaccccacccataaatcga
cagctattgaccatgttaaacacaccctttagtttctcatatcaaaaggcccacagagat
tttggatatagccctcgctatgactgggaagaggcacgcaggcgcactactgattggcta
gcgtctgtcttgcctatagagagacaaagattgaactcgaaataa
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