KEGG   Thermus scotoductus: TSC_c17960
Entry
TSC_c17960        CDS       T01414                                 
Symbol
ligA
Name
(GenBank) DNA ligase, NAD-dependent
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
tsc  Thermus scotoductus
Pathway
tsc03030  DNA replication
tsc03410  Base excision repair
tsc03420  Nucleotide excision repair
tsc03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:tsc00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    TSC_c17960 (ligA)
   03410 Base excision repair
    TSC_c17960 (ligA)
   03420 Nucleotide excision repair
    TSC_c17960 (ligA)
   03430 Mismatch repair
    TSC_c17960 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:tsc03032]
    TSC_c17960 (ligA)
   03400 DNA repair and recombination proteins [BR:tsc03400]
    TSC_c17960 (ligA)
Enzymes [BR:tsc01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     TSC_c17960 (ligA)
DNA replication proteins [BR:tsc03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     TSC_c17960 (ligA)
DNA repair and recombination proteins [BR:tsc03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     TSC_c17960 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     TSC_c17960 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     TSC_c17960 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      TSC_c17960 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 Nlig-Ia PTCB-BRCT DNA_ligase_ZBD HHH RNA_pol_A_CTD BRCT_2 Zn_ribbon_3
Other DBs
NCBI-ProteinID: ADW22410
UniProt: E8PLZ1
LinkDB
Position
complement(1699649..1701673)
AA seq 674 aa
MTLEEARKRINELRDLIRYHNYRYYVLDAPEISDAEYDRLLRELKELEERFPELKSPDSP
TEQVGAKPLEATFRPIRHPTRMYSLDNAFTLEEVRTFEERIERALGRKGPFVYTVEHKVD
GLSVNLYYEEGILVWGATRGDGETGEEVTQNLLTIPTIPRRLKGVPERLEVRGEVYMPIE
AFLRLNEELEEKGEKIFKNPRNAAAGSLRQKDPRITARRGLRATFYALGLGLEESGLKTQ
LDLLHWLREKGFPVEHGFARAEGAEGVERIYQGWLKERRSLPFEADGVVVKLDELSLWRE
LGYTARAPRFAIAYKFPAEEKETRLLQVVFQVGRTGRVTPVGILEPVFIEGSEVSRVTLH
NESYIEELDVRIGDWVLVHKAGGVIPEVLRVLKEKRTGEERPIRWPETCPECGHRLVKEG
KVHRCPNPLCPAKRFEAIRHYASRKAMDIGGLGEKLIEKLLEKGLVKDVADLYRLKEEDL
VGLERMGKKSAGNLLRQIEESRSRGLERLLYALGLPGVGEVLARNLAAHFGTMDRLLEAS
LEELLQVEEVGELTARGIYETLQDPAFRDLIRRLKEAGVEMEAKERGEEALKGLTFVITG
ELSRPREEVKALLRRLGAKVTDSVSRKTSYLVVGEAPGSKLEKARALGVPTLTEEELYRL
IEERTGKPVETLAS
NT seq 2025 nt   +upstreamnt  +downstreamnt
atgaccctggaagaggcacgcaaacggatcaacgagctccgggacctcatccgctaccac
aactaccgttactacgtcctggatgccccggagatttccgatgccgaatacgaccggctt
ttgagggagcttaaggagttggaggaacgctttcccgagctcaaaagcccggattccccc
acggagcaagtgggggctaagcccctcgaggccaccttccgccccatccgccatcccacc
cgcatgtactctctggataacgccttcaccctggaggaggtcaggacctttgaggagcgg
atcgagcgggccttggggaggaaggggcccttcgtgtacacggtggagcacaaggtggat
ggcctttccgtgaacctctactacgaggaagggattctggtatggggggccacccggggg
gacggggaaacaggggaggaggtcacccagaacctcctcaccatccccaccattccccga
aggcttaaaggggtaccggagcgcctcgaggtccggggcgaggtgtacatgcccatagag
gccttcctccgcctcaacgaggagctggaggaaaagggagagaagatcttcaaaaacccc
agaaacgccgccgccggctccctcaggcagaaggacccccggatcaccgcaaggaggggc
ctcagggccaccttctacgccctgggcctcggcctggaggaaagcgggctcaagacccag
ctggacctccttcactggcttagggagaaggggtttcccgtggagcacggcttcgcccgg
gcagaaggggcagagggggtggaaaggatctaccagggctggctgaaggagcggcgaagc
ctgccctttgaggcggatggggtggtggtgaagctggatgagctttccctctggcgggaa
ctggggtacaccgcccgggccccgcgctttgccatcgcctacaagttccccgcggaggag
aaggaaacccgcctgcttcaggtggtcttccaggtggggcgcacgggcagggtgacgccg
gtgggcatcctggagcccgtcttcattgagggaagcgaggtcagccgggttaccctgcac
aatgaaagctacattgaggagctggacgtgcgcatcggggactgggtcctggtgcacaag
gcggggggggtgatccccgaggtcctcagggtcctgaaggagaagaggaccggggaggag
aggcccattcgctggccggaaacctgtcccgagtgcggccaccgcctggtcaaggagggc
aaggtgcaccgctgccccaatcccttgtgcccggccaagcgctttgaggccatccgccac
tacgcctcccgcaaggccatggacatcgggggtcttggggagaagctcattgagaagctc
ctggaaaagggcttggtgaaggatgtggccgacctttaccggcttaaggaggaggacctg
gtgggcctcgaacgcatggggaagaagagcgcggggaaccttctccgccagattgaggag
agccggagccggggcctggagcggctcctctatgctctgggactgccgggggtgggggag
gtgctggcccgcaacctggcagcccacttcggcaccatggaccgcctcctcgaggccagc
ctggaggaactcctccaggtggaggaggtgggggaactcaccgcccgggggatttacgaa
accctgcaggaccctgccttccgggacctgataaggcgcctcaaggaggctggggtggag
atggaggccaaggaacggggggaggaggctttaaagggccttaccttcgtcatcaccggg
gagctttcccgcccccgggaggaggtgaaggccctcttgaggcgcctgggggccaaggtg
acggattccgtgagccgcaagaccagctacctggtggtgggggaggctccggggagcaag
ctggagaaggcccgggccctgggggtgcccaccttgacggaggaggagctgtacaggctc
atagaggagcgcacggggaagcctgtggaaaccttagcttcctag

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