KEGG   Thioalkalivibrio paradoxus: THITH_09580
Entry
THITH_09580       CDS       T03590                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
tti  Thioalkalivibrio paradoxus
Pathway
tti03030  DNA replication
tti03410  Base excision repair
tti03420  Nucleotide excision repair
tti03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:tti00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    THITH_09580 (ligA)
   03410 Base excision repair
    THITH_09580 (ligA)
   03420 Nucleotide excision repair
    THITH_09580 (ligA)
   03430 Mismatch repair
    THITH_09580 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:tti03032]
    THITH_09580 (ligA)
   03400 DNA repair and recombination proteins [BR:tti03400]
    THITH_09580 (ligA)
Enzymes [BR:tti01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     THITH_09580 (ligA)
DNA replication proteins [BR:tti03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     THITH_09580 (ligA)
DNA repair and recombination proteins [BR:tti03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     THITH_09580 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     THITH_09580 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     THITH_09580 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      THITH_09580 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 Nlig-Ia DNA_ligase_ZBD HHH PTCB-BRCT PP2C_2
Other DBs
NCBI-ProteinID: AHE98474
UniProt: W0DIM6
LinkDB
Position
complement(2033910..2035931)
AA seq 673 aa
MTSLTDAAPARRAAELRERIAHHDWRYYVLDDPEVSDAEYDQLFRELQRLEAEHPELVVP
ESPTQRVSGALTGGFTAVRHRLPMLSLNNAFSEDEIRSFDRRVRERLDADAAVDYMAEPK
LDGLAISLLYRDGRLVRAATRGDGETGEDVTGNVRTVRAIPLALSGSQWPDEFEVRGEVF
MRRRDFERLNQRLQDAGERGFMNPRNAAAGSLRQLDPAVTASRPLSFFAYGPGAVGDYPL
PETQSAVLDWFGSLGIPVCPERARVSGVDAALAYYRELAQRRAALPYDIDGVVFKVDARE
AQQRIGFVARAPRWAIAYKFPAEERTTRLVAVDFQVGRTGALTPVARLEPVLVGGVMVSN
ATLHNMDEVARKDVRIGDRVVVRRAGDVIPEVVGRAGGERDPQTQAIELPAACPECGSRV
EQEDGKAVARCTGGLVCPAQRREALRHFVSRKALDIEGFGERLIEQLVASGTVANPAELF
ALDAGQLEVFERIGPKSAQNLERALQQARETTLARFVYALGIREVGEVTARALAAHFGAL
EPLMQASVEELESIRDVGPVVARHVASFFAEPHNCEVIAALRAAGVHWSESEPADTGVRP
LEGHTYVLTGSLEEMTREQASERLQALGAKVTGNVSRQTTAVIAGASPGSKRARAEALGV
PVLDEAALRELIG
NT seq 2022 nt   +upstreamnt  +downstreamnt
gtgacgtccctcacggacgccgcgcccgcccgccgggccgcggaattgcgtgaacggatc
gcgcatcatgattggcgctattacgtgctggacgacccggaggtcagcgacgccgagtac
gaccagctgttccgggagctccagcggctcgaggccgaacatccggaactggtggtgccg
gagtcgccgacccagcgggtcagcggagcgctcaccggcgggtttacagcggtgcggcat
cgcctgccgatgctgtcgctgaacaacgcgttctccgaagacgaaatccggtcgttcgac
cggcgcgtccgcgagcgcctcgacgcggatgccgcggtcgattacatggccgagcccaag
ctcgacgggctcgcgatcagcctgctctatcgggacggtcgcctggtgcgggcggccacg
cgcggcgatggcgagaccggcgaggacgtgaccgggaacgtgcgcaccgtgcgcgcgatt
ccgctggcgttgtcgggatcgcagtggccggacgagttcgaggtgcgtggcgaggtgttc
atgcgccgccgggatttcgaacgcctgaaccaacgcctgcaggacgccggcgaacgtggc
ttcatgaatccgcgcaatgccgcggccggaagcctgcgccaactcgatccggcggtgacc
gcaagccggccgctgagcttcttcgcctatggtccgggtgcggtgggcgactacccgctg
ccggagacgcaatccgccgtgctcgactggttcggttcgctcgggatcccggtgtgcccc
gagcgggcccgggtctcgggggtcgacgccgcgctcgcgtactaccgggagctggcgcag
cgccgcgcggcactgccctacgacatcgacggcgtggtgttcaaggtcgatgcgcgggag
gcgcagcagcgcatcgggttcgtggcccgcgcaccgcgctgggcgattgcgtacaagttc
ccggccgaggagcgcactacccggctggtcgcggtggatttccaggtcgggcgcacgggg
gccctgaccccggtggcgcggctggagccggtgctggtcggcggggtgatggtcagcaat
gccacgctgcacaacatggacgaggttgcacgcaaggacgttcgcatcggcgaccgcgtg
gtggtccgccgggccggcgacgtgatcccggaggtggtcgggcgcgcgggcggcgagcgc
gacccgcagacgcaggcgatcgaactgcccgctgcctgccccgagtgcggctctcgggtg
gagcaggaagacggcaaggcggtggcgcgctgcaccggcggtctggtctgtccggcgcag
cggcgcgaggcgcttcgccacttcgtctcgcgcaaggcgctggacatcgagggcttcggg
gaacggctgatcgagcagctggttgcgtcgggtacggtggccaacccggccgagctgttc
gcgctcgatgccgggcaactcgaggtcttcgagcgtatcgggccgaaatcggcgcagaat
ctcgagcgggcgctgcaacaggcccgggaaacgaccctggcccggttcgtctacgcgctc
gggatccgcgaggtcggcgaggtgactgcgcgtgcgctggccgcgcatttcggcgcactg
gaaccgctgatgcaggcctcggtggaggaattggaatcgatccgcgatgtcggtccggtc
gtcgcgcggcatgtcgcgagctttttcgcggagccccacaactgcgaggtgatcgccgcc
ctgcgcgctgccggcgtgcactggtccgagtccgagccggcggatacgggcgtacggccg
ctcgaggggcatacctacgtgttgaccggaagcctcgaggagatgacgcgcgagcaggcg
agcgagcgcctgcaggcgttgggcgcgaaggtcaccggcaacgtctcacggcagacgacc
gcggtgatcgccggcgccagtccgggatccaagcgggcgcgcgccgaggccctgggcgtt
ccggtgctggacgaggccgcgcttcgagagttgatcggctga

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