Thermus thermophilus HB8: TTHA0185
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Entry
TTHA0185 CDS
T00220
Symbol
TTHA0185
Name
(GenBank) pyruvate dehydrogenase complex, pyruvate dehydrogenase E1 component
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
ttj
Thermus thermophilus HB8
Pathway
ttj00010
Glycolysis / Gluconeogenesis
ttj00020
Citrate cycle (TCA cycle)
ttj00620
Pyruvate metabolism
ttj00785
Lipoic acid metabolism
ttj01100
Metabolic pathways
ttj01110
Biosynthesis of secondary metabolites
ttj01120
Microbial metabolism in diverse environments
ttj01200
Carbon metabolism
ttj01210
2-Oxocarboxylic acid metabolism
Module
ttj_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ttj00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
TTHA0185 (TTHA0185)
00020 Citrate cycle (TCA cycle)
TTHA0185 (TTHA0185)
00620 Pyruvate metabolism
TTHA0185 (TTHA0185)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
TTHA0185 (TTHA0185)
Enzymes [BR:
ttj01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
TTHA0185 (TTHA0185)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
BAD70008
UniProt:
Q5SLV8
LinkDB
All DBs
Position
1:complement(180308..183025)
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AA seq
905 aa
AA seq
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MTEKELKAAFQALSPEEKARFLEIENREWLESLEYVLKVEGPERVEELLRLLDEYLFRHG
VYPANRLSTPYLNTLPKEKEPPYPGDLELERRIANILRWNVAMMVTRANKKADGIGGHIA
TYASIAELYEVGFNHFFRGPEAGLDRDLVFFQGHASPGNYARAFLEGRLKEEDLENFRRE
VHPPVPGGRGLSSYPHPWLMPDFWEFPTVSMGLGPIQAIYQARFMRYLEDRGLKPKSSAK
VWAFLGDGEHDEPETVGALHLAARENLDNLIFVVNCNLQRLDGPVRGNSKVIQELERLYR
GAGWRVIKVVWGSAWDELLAKDKEGHLLRRFEALVDGESQRYAAFGGKELRERFFNTPEL
KKLIEGMTDEELTELTRSRGGHDMVKIYAAYKAAVEHRGSPVVILARTIKGYGMGPTVMA
KNVAHQVKKLTEEDLKEARRFLGIPIPEEKLPELPYYHPGPDSPEVRYLLERRKALGGFV
PERRVRFQGGLEVPEEEFFREFYEGSGGREISTTMAFVRILAKLLRHPKIGKYIVPIVPD
EARTFGMEALIAQVGVYSPQGQLYVPVDAGTLTAYKESQKGQILEEGITEAGAMAEFIAA
GTAYAHWGIPTIPFFITYSMFGLQRIGDLVWAAADQRARGFFLGATAGRTTLAGEGLQHQ
DGQSHVYALAAPNLLAYDPAFAYEFAVILEDGLRRMYGRGEDVFYYITIENENYVHPPMP
EPREKVKEGILKGLYLFRAGEGKGPKVQLFGTGPILNEALKAQELLAKYGVVADVWSATS
YKALYVDAIEAERETRLLGKARRPYVQEALEGHEGPIVAATDYLKALPNLIRGYVDRPFA
VLGTDGFGRSDTREALRDFFEVDARHIAYTALALLHGEGKVTKRTLNQARKDLGLKLEEV
PPHRR
NT seq
2718 nt
NT seq
+upstream
nt +downstream
nt
atgacggaaaaggagctgaaggcggccttccaggccctttcgcccgaggagaaggcccgc
ttcctagaaatagagaaccgggagtggctggagtctttggaatacgtcctcaaggtggag
ggccccgagcgggtggaggagctcttgcgccttctggacgagtacctcttccgccatggg
gtctaccccgcaaaccgcctctccaccccctacctcaacaccctccccaaggagaaagag
cccccttaccccggggacctggagctggagcgccgcatcgccaacatcctccgctggaac
gtggccatgatggtcacccgggccaacaagaaggcggacggcatcggggggcacatcgcc
acctacgcctccatcgccgagctttacgaggtgggcttcaaccacttcttccgcgggccg
gaggcggggctggaccgggacctcgtcttcttccagggccacgcctcccccgggaactac
gcccgggcctttttggaggggcggcttaaggaggaggacctggagaacttccgccgcgag
gtccaccccccggtgccggggggccgggggctttccagctacccccacccttggctcatg
cccgacttctgggagttccccacggtctccatgggcctcggccccatccaggccatctac
caggcgcgcttcatgcgctacctcgaggaccgaggcctcaagcccaaaagctccgccaag
gtctgggccttcctcggggacggggagcacgacgagcccgagacggtgggggcgcttcac
ctcgccgcccgggagaacctggacaacctcatcttcgtggtgaactgcaacctccagcgc
ttagacggccccgtgcggggcaactccaaggtcatccaggagctggaaaggctctacagg
ggcgcgggctggcgcgtgatcaaggtggtctggggttcggcctgggacgagctcctcgcc
aaggataaggagggccacctcctccgccgctttgaggccctggtggacggggagagccag
cgctacgccgccttcgggggcaaggagctaagggagcgcttcttcaacacccccgagctt
aagaagctcattgaggggatgacggacgaggagctcaccgagctcacccggtcccggggc
ggccacgacatggtcaagatctacgccgcctacaaggccgcggtggagcacaggggaagc
cccgtggtcatcctcgcccggaccatcaagggctacgggatgggccccacggtcatggcc
aagaacgtggcccaccaggtgaagaagctcaccgaggaggacctgaaggaggcgaggcgc
ttcctcggcatccccattcccgaggagaagcttcccgagctcccctactaccacccgggg
ccggactcccccgaggtccgctacctcctggaacggaggaaggccctgggcggcttcgtg
cccgaaaggagggtgcgcttccaggggggcctcgaggtcccggaggaggagttcttccgg
gagttctacgagggctcaggggggcgggagatctccaccaccatggccttcgtgcgcatc
ctcgccaagctcctccgccaccccaagatcggcaagtacatcgtccccatcgtccccgac
gaggcccgcacctttggcatggaggccctgatcgcccaggtgggcgtctactccccccag
gggcagctctacgtccccgtggacgcgggcaccctcaccgcctacaaggagagccagaag
gggcagatcctggaggaggggatcaccgaggccggggccatggccgagttcatcgccgcc
gggaccgcctacgcccactggggcatccccaccatccccttcttcatcacctactccatg
ttcggcctgcaaaggatcggggacctcgtctgggccgccgccgaccagcgcgcccggggc
ttcttcctcggggccacggcggggcgcaccaccttggcgggggagggccttcagcaccag
gacggccaaagccacgtctacgccctggccgcccccaacctcctcgcctacgatcccgcc
ttcgcctacgagttcgccgtgatcctggaggacggcctccgccgcatgtacggccggggg
gaggacgtcttctactacatcaccattgagaacgagaactacgtccacccccccatgccc
gagccccgggaaaaggtcaaggaggggatcctaaaagggctttacctcttccgggcgggg
gaggggaagggcccaaaagtgcagcttttcggcaccgggcccatcctcaacgaggccctg
aaggcccaggagcttttggccaagtacggcgtggtggcggacgtctggagcgccaccagc
tacaaggccctctatgtggacgccattgaggccgagcgggagacccgccttttgggcaag
gcccgcaggccctacgtgcaggaggccctcgagggccacgaggggcccatcgtggccgcc
accgactacctcaaggccctacccaacctcatccggggatacgtggaccggcccttcgcc
gtcctcggcacggacggcttcggccgctccgacacccgggaggcccttagggacttcttt
gaggtggacgcccggcacatcgcctacaccgccctggccctgctccacggggagggcaag
gtgacgaagaggaccctgaaccaggcgaggaaggacctgggccttaagctggaggaggtg
ccgccccaccggcggtag
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