KEGG   Thermus thermophilus HB8: TTHA0729
Entry
TTHA0729          CDS       T00220                                 
Symbol
TTHA0729
Name
(GenBank) probable efflux transporter, AcrB/AcrD/AcrF family
  KO
K18138  multidrug efflux pump
Organism
ttj  Thermus thermophilus HB8
Pathway
ttj01501  beta-Lactam resistance
ttj01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:ttj00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    TTHA0729 (TTHA0729)
   01503 Cationic antimicrobial peptide (CAMP) resistance
    TTHA0729 (TTHA0729)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ttj02000]
    TTHA0729 (TTHA0729)
   01504 Antimicrobial resistance genes [BR:ttj01504]
    TTHA0729 (TTHA0729)
Transporters [BR:ttj02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   TTHA0729 (TTHA0729)
Antimicrobial resistance genes [BR:ttj01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    TTHA0729 (TTHA0729)
SSDB
Motif
Pfam: ACR_tran SecD_SecF_C Patched
Other DBs
NCBI-ProteinID: BAD70552
UniProt: Q5SMF3
LinkDB
Position
1:complement(692987..696286)
AA seq 1099 aa
MRENPLVAFFVERFVFATSIFVGMVLVGLLLGLGLGVELLPRFSVPVIAISTSYPGAGPE
EVAEQVSKPLEDALSTLTGVDVIGSSSTEGFSLVFVQFKQGVDVDQGAVEASQKVAAIRS
TLPKDASAPVVQKFDPSASPILYLALEAPGEDLAEVLRYAERTLKPRLQLVSGVADIRLT
GAPKTAIKVYLDPDRLQALGIPPLQVVQALSASALNLPLGALTEEERRLVYTLRATPRTA
SEVAEVLVDPGRGIRVRDVARVEEAREAPTTLNRVNGRPAVVLAVVKTPDANAVAVAQEV
RRALEETSLPPGYRAEVALDTTRFIQAAVEDTVREAFLAALAVSLVVLVFLGKLNSVFSV
ILAIPITLSGAILLFGVLGFTYNLISLLALTVAVGIVVDDSIVVAENIDRYRRMGLGLKE
AVLKGASEVSAAVAAATLSLLAVFLPISFLPGLIGQIFQQFGLGMAAAIGVSWLEALLFL
TVRLAYFPDPDPPTLKEALRAALLLPKDLAWAYRRGFRTALGLLLGLGVAFLLYRQGPLH
LLLLVLYPALLGLGRYLGRLLLDLAGALARLLHEATEGGVRRLTEGYARALEAALARPYL
VLGLAGLAFLSVFPILPRIPFNFTPRADTGVLTATLLLPKDTPLSVSDRAARALEAYFLA
HPAVERVVTTVGASATGGAQVGDPSRVQLQIVLKPKGERPDIFTLTEVFNREGKEALKDF
PGADLRVLAQTGPEAGDADLQFFVTGPDREVLEARVQAIVDRIAEKPYVLNVKSTLEATQ
RERVFVPDPARLSGTGLTPQDVAQTLRLYLSGTQAATARRSGEEYPVVVQADPLRYSGEG
GLLSLPVYAPALQAFLPLGSLGRFEERPSPTLISRRNQAYAAGININLKPEAPGALQVQA
ELEQDLRAAGLLGDGVELVASGLGSFTEELASLAPLAFGLALVLNYLVIASQFNAWRYPL
YLLLPVPLALVGAFWLTYFLGTGLDVISVLGVVMLIGLVTKNAILLLDFASRRMREKPLK
EALVEAARLRLRPILMTTLTVLIISLPLLLGAGEGSEYRRPLGVVILGGMLSSTLLTLFV
VPAAFFAVEGRLARKGGKG
NT seq 3300 nt   +upstreamnt  +downstreamnt
gtgagggaaaaccccctggtggccttcttcgtggagcgcttcgtcttcgccacctccatc
ttcgtgggcatggtcctggtggggctccttctgggcctcgggcttggggtggagctcctt
ccccggttcagcgtccccgtcatcgccatctccaccagctaccccggggccgggcccgag
gaggtggcggagcaggtctccaagcccctggaggacgccctctccaccctcacgggggtg
gacgtcatcggctccagctccacggaggggttcagcctggtcttcgtccagttcaagcaa
ggggtggacgtggaccagggagcggtggaggcgagccagaaggtggccgccatccggagc
accctccccaaggacgcctccgcccccgtggtgcagaagtttgacccctcggcgagcccc
atcctctacctggccctcgaggccccgggggaggacctcgccgaggtcctccgctacgcg
gagaggaccctcaagccccgcctccagctggtctccggcgtggccgacatccggctcacg
ggcgcccccaagacggccatcaaggtctacctggaccccgaccggctccaggccctgggg
atccctcccctccaggtggtccaggccctctccgcctcggccctcaacctccccttgggg
gccctcacggaggaggagcggcgcctggtctacaccctacgcgccaccccccgcaccgcc
tcggaggtggccgaggtcctggtggacccgggccggggcatccgggtgcgggacgtggcc
cgggtggaggaggcccgggaggcccccaccaccctgaaccgggtgaacggccgccccgcc
gtggtcctggccgtggtcaagacgccggacgccaacgccgtggccgtggcccaggaggtg
aggcgggccctggaggagacctccctcccccccgggtaccgggcggaggtcgccctggac
accacccgcttcatccaggccgcggtggaggacacggtgcgggaggcgttcctggccgcc
ctggccgtctccctggtggtcctcgtcttcctggggaagctcaactccgtcttctccgtc
atcctggccatccccatcaccctctccggggccatcctcctcttcggcgttttgggcttc
acctacaacctcatcagcctcctcgccctcaccgtggcggtgggcatcgtggtggacgac
tccatcgtggtggcggaaaacattgaccgctaccgccgcatggggcttggcctcaaggag
gcagtactcaagggggcgagcgaggtgagcgccgccgtggccgcggccacccttagcctc
ctcgccgtcttcctccccataagcttcctcccgggcctcatcggccagatcttccagcag
ttcggcctgggcatggcggcggccatcggggtgagctggctcgaggccctcctcttcctc
accgtccgcctcgcctacttccccgaccccgacccccccaccctcaaggaggccctgcgg
gcggccctcctcctccccaaggacctcgcctgggcctaccgccggggcttccgcaccgcc
ttgggcctcctcctcggcctcggcgtggccttcctcctctaccgccaaggccccctccac
ctcctcctcctcgtcctctacccggccctcctcggcctcgggcgctacctggggaggctc
cttctggacctcgccggggccctggcccggctcctgcacgaggccacggaggggggggtg
cgaaggctcaccgaggggtacgcccgggccctggaggccgccctcgcccggccctacctg
gtcctgggcctggcgggcctcgccttcctctccgtcttccccattttgccccggatcccc
ttcaacttcaccccccgcgcggacaccggggtgctcaccgccaccctcctcctccccaag
gacacgcccctctccgtctccgaccgggcggcgcgggccctagaggcctacttcctcgcc
cacccggcggtggagcgggtggtgaccaccgtgggggcgagcgccaccgggggggcccag
gtgggggacccctcccgggtccagctccagatcgtcctcaagcccaaaggggagcggccg
gacatcttcaccctcaccgaggtcttcaaccgggagggcaaggaggcgcttaaggacttc
cccggagcggacctccgcgtcttagcccagaccggccccgaggcgggggacgcggacctc
cagttcttcgtcaccggccccgaccgggaggtgctggaggcccgggtccaggccatcgtg
gaccggatcgcggagaagccctacgtcctgaacgtgaagagcaccctggaggccacccag
cgggagcgcgtcttcgtccccgaccccgccaggctctccggcaccggcctcactccccag
gacgtggcccagaccctgaggctctacctctccgggacccaggcggccacggccaggcgg
agcggggaggagtaccccgtggtggtgcaggccgaccccctccgctactccggggagggc
ggcctcctctccctccccgtctacgcccccgccctccaggccttcctgcccttaggaagc
ctcggccggtttgaggagcgcccctcccccaccctgatctcccgccgcaaccaggcctac
gccgccgggatcaacatcaacctcaagcccgaggccccaggggccctccaggtccaggcg
gagctggagcaggacctcagggcggcggggctccttggggacggggtggagctcgtggcc
tcggggcttgggagcttcacggaggagctcgcctccctcgcgcccctcgccttcggcctc
gccctcgtcctcaactacctcgtcatcgccagccagttcaacgcctggcgctaccccctc
tacctcctcctccccgtgcccttggccctggtgggggccttctggctcacctacttcctg
ggcacgggcctggacgtgatcagcgtcttgggggtggtgatgctcatcggcctggtgacc
aagaacgccatcctcctcctggacttcgcctcccgccgcatgcgggaaaagcccctcaag
gaggccctggtggaggcggccaggctcaggctgaggcccatcctcatgaccaccctcacc
gtcctcatcatcagcctccccctcctcctcggggccggggaggggtcggagtaccgcagg
cccttgggcgtggtcatcctgggggggatgctctcctccaccctcctcaccctcttcgtg
gtccccgccgccttcttcgcggtggaggggcgcctcgcgcggaaggggggaaaggggtga

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