KEGG   Thermochromatium tepidum: E6P07_00200
Entry
E6P07_00200       CDS       T06573                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
ttp  Thermochromatium tepidum
Pathway
ttp03030  DNA replication
ttp03410  Base excision repair
ttp03420  Nucleotide excision repair
ttp03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:ttp00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    E6P07_00200 (ligA)
   03410 Base excision repair
    E6P07_00200 (ligA)
   03420 Nucleotide excision repair
    E6P07_00200 (ligA)
   03430 Mismatch repair
    E6P07_00200 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ttp03032]
    E6P07_00200 (ligA)
   03400 DNA repair and recombination proteins [BR:ttp03400]
    E6P07_00200 (ligA)
Enzymes [BR:ttp01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     E6P07_00200 (ligA)
DNA replication proteins [BR:ttp03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     E6P07_00200 (ligA)
DNA repair and recombination proteins [BR:ttp03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     E6P07_00200 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     E6P07_00200 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     E6P07_00200 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      E6P07_00200 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 HHH_5 BRCT Nlig-Ia DNA_ligase_ZBD HHH PTCB-BRCT 5_3_exonuc Transposase_20 UPF0758_N DUF4796_N
Other DBs
NCBI-ProteinID: QGU31550
UniProt: A0A6I6EBL9
LinkDB
Position
43948..46029
AA seq 693 aa
MTSSDIARRIEALRAEIRHHNHRYYVLDDPEIPDAEYDRLFAELQRLEAEHPELITPDSP
TQRVGAEVRPDLSEVRHSVPMISLDNAMNDAQLVEFHRRITAALPELDPVPYTAEPKFDG
LAISLRYESGVLVLAATRGDGTRGEDVTHNARVIPSVPLRLLGGDWPEVLEVRGEVYMPR
AGFDRLNADLEARGERPFANPRNAAAGSLRQLDPRIAAQRPLRFCAYGWGEISGETGTSQ
FEMLQRLAGWGLPISPELRRVAGLDGCRAYFEALAQRRAVLDYDIDGVVFKLDHLPAQAA
LGATAHHPRWAIARKFPAQEALTEVEAVEFQVGRTGAVTPVARLRPVRIGGVTVSKATLH
NLDEVRRKDVRIGDTVSIRRAGDVIPEIVRVLVERRPDGARPVELPTRCPVCGSDVIQPE
GEAVARCSGGLWCPAQRKEAIRHFASRRALDIEGLGEKLIEQLVDLDWVREPADLYGLTA
DRLASLDRMGERSAANLIAALERSKETTLARFVFALGIRGVGETTAQQLAEHFGRIEALM
AARVEELVTIKGIGPVVAAHIVGFMAQPHNRAAIAHLLAAGIHWPEVERSASAPAEPSAL
PLSDKTFVITGTLSRPRHAVAAQLRALGAKVTESLSKKTDYLLAGTAPGSKLAQAERLGV
RVIDEAGLDTLIARHQLPLEGEAISRDTTGGMR
NT seq 2082 nt   +upstreamnt  +downstreamnt
gtgacctcctcggatatcgcccggcgcatcgaggcgctgcgcgccgagatccgccatcac
aatcatcgctattatgtactcgacgacccggagatcccggacgccgagtacgatcggctg
tttgccgagctccagcgcttggaggccgaacaccccgagctgatcacccccgactcgccc
acccagcgggtcggcgccgaggtgcgtccagatctcagcgaggttcggcattccgtcccc
atgatctcgctcgacaatgcgatgaacgacgcgcagctggtcgagttccatcgtcgtatc
accgccgccctgcctgagctcgatcctgtgccctataccgccgagcccaagttcgacggc
ctggcgatcagcctgcgttatgagtccggcgtcctggtgttggccgccacccgtggcgat
ggcacgcgcggcgaggacgtgacccacaatgcgcgcgttatcccgagcgtgccgctgcgg
cttttggggggggactggcccgaggtgttggaggtgcgcggcgaggtctatatgccgcgc
gccggattcgatcggctcaacgccgacctggaggcgcgcggcgagcgtcccttcgccaat
ccgcgcaacgccgccgccggcagcctgcgtcagctcgatccgcgcatcgccgcccagcgc
ccgttgcgcttttgcgcctatggctggggcgagatttcgggcgagacgggcacgagtcag
ttcgagatgctccagcgtctggcgggttgggggttaccgatctcgcccgagctgcggcgg
gtggcgggactcgacggctgtcgcgcctatttcgaggcattggcgcagcgacgcgcggtg
ctcgactacgacatcgacggggtggtgttcaaactcgaccacctgccggcacaggcagcg
ctcggggccacggcacaccatccgcgctgggccatcgcgcgcaagtttccggcccaggag
gccctgaccgaggtcgaggcggtcgagttccaggtcgggcgcaccggggcggtgaccccg
gtagcgcgactgcgtccggtaaggatcggcggcgtgaccgtctccaaggccacgctgcac
aatctcgacgaggttcggcgcaaggacgtgcgcatcggggataccgtctccatccgccgc
gcgggcgatgtgatccctgagatcgtccgtgtgctggtcgagcggcgtccggacggggcg
cgtccagtcgaactaccgacccggtgtccggtctgcgggtcggacgtgatccagcccgag
ggcgaggcggtcgcacgctgtagcggtgggctttggtgtccggcccagcgcaaggaggca
atccggcattttgcctcgcgccgggcactggatatcgaagggctgggcgagaagctcatc
gagcaactggtcgatctggactgggtgcgcgagccggcggatctctatggtctgactgcc
gaccgcttggcctcgttggaccgcatgggcgagaggtcggcagccaatctgatcgcggcg
ctggagcgcagcaaagagacgacgctggcgcgcttcgtctttgcgctcgggatccgcggg
gtcggtgagaccacggcgcaacaactggcagagcatttcggcaggatcgaggcgctgatg
gcggcgcgcgtcgaggagctggtcacgatcaagggcatcggcccggtggtggcggcccac
atcgtcggttttatggcccagccgcacaatcgcgcggcgatcgcccatctgcttgccgct
gggatccactggcccgaggtcgagcgctcggcttcagcccccgccgaaccgagcgcctta
cccctgagcgacaagaccttcgtcatcaccggtacgctcagccgcccgcgtcacgcggtg
gcggcccagttgcgcgccctgggcgccaaggtgacagagagcctctccaagaagaccgat
tatctcctggcaggtacggcgcccgggtcgaagctcgcccaggccgagaggctgggggtg
agggtgatcgatgaggccgggctggacaccttgatcgcgcggcaccagctcccacttgag
ggggaagccatttccagagacaccacagggggtatgcgatga

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