KEGG   Thermochromatium tepidum: E6P07_09285
Entry
E6P07_09285       CDS       T06573                                 
Symbol
metH
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
ttp  Thermochromatium tepidum
Pathway
ttp00270  Cysteine and methionine metabolism
ttp00450  Selenocompound metabolism
ttp00670  One carbon pool by folate
ttp01100  Metabolic pathways
ttp01110  Biosynthesis of secondary metabolites
ttp01230  Biosynthesis of amino acids
ttp04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:ttp00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    E6P07_09285 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    E6P07_09285 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    E6P07_09285 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    E6P07_09285 (metH)
   04980 Cobalamin transport and metabolism
    E6P07_09285 (metH)
Enzymes [BR:ttp01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     E6P07_09285 (metH)
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding AIRC
Other DBs
NCBI-ProteinID: QGU33149
UniProt: A0A6I6EDU6
LinkDB
Position
complement(2022163..2025924)
AA seq 1253 aa
MIDSNTLIHERLARSILILDGAMGTMIQRQGLTEADYRGARFADWPRDLKGNNDLLVLTR
PEVIDGIHRAYLEAGADIIETNSFNATRIAMADYGMEGLVYEINVAAARLARAAADAYAT
PEKPRFVAGVLGPTNRTASISPDVNDPGARNIDFDTLVAAYAESARGLIAGGADLILIET
IFDTLNAKAAIFAVKQVFDEDGVERPIMLSGTITDQSGRTLTGQTTEAFYNSLRHAEPLS
VGLNCALGPFELRQYVEELARISEFHVSAHPNAGLPNALGGYDLGPEVMATEIAEWARAG
FLNIVGGCCGTTPDHIRAIAEAVAGLPPRVRPTIEPACRLAGLEPLNIGPDTLFVNVGER
TNVTGSARFRRLIKEGDYDTALSIAQEQVDNGAQIIDVNMDEGLLDAVAAMRRFLNLIAA
EPEIARVPVMIDSSKWEVIETGLKCVQGKPIVNSISLKEGEQRFIDQARLCRRYGAAVIV
MAFDEQGQADTQARKVEICTRAYRLLTERVGFPPEDIIFDPNIFAVATGIEEHDHYAVDF
IEATREIKRTLPHALVSGGVSNVSFSFRGNEPVRQALHAVFLYHAIRAGMDMGIVNAGQL
AIYDELPEELRDAVEDVILNRRPDATERLLELAPRYQGEGAGPENRSDLEWRTWPVEKRL
EHALVKGIADFIDEDTEAARQTLGRPLAVIEGPLMQGMDLVGDLFGAGKMFLPQVVKSAR
VMKKAVAYLQPFLEAEQAEGGAEASSNGKFLIATVKGDVHDIGKNIVAVVLQCNGYEVID
LGVMVPAETILQRARAVGADVIGLSGLITPSLDEMVHVAKEMQRQGLELPLLIGGATTSK
LHTALKIAPQRTAPVIYVPDASRAVGVVSNLLSETQRPGYVAAIAEEYERLRAERDGRAA
TRKSVSILEARANRPALDWAGYEPPRPALLDPEFSETAPWSLALERAGETVIATLADFPL
DDLVHTIDWLPFFRAWELAHSRFPDILDDPVIGEEARMLYAEAQVFLERLVAERWLQARA
VFGFFPANGIGDDDIALYADAARTQRLATLHHLRQQMPRAGGRQQANFCLSDFIAPAECG
RPDWIGAFAVTAGVGIEGPLARFVADQDDYSAILLKALADRLAESFAERLHQLVRTRYWG
YATDEQLSNEELIAEHYRGIRPAPGYAACPDHTEKGTLWRLLEPDRRIGLILTENFAMLP
AASVSGWYFAHPEARYFGVGRIQRDQVEDYAQRKGWTLDEAERWLAPVLGYEP
NT seq 3762 nt   +upstreamnt  +downstreamnt
atgatagattccaataccctgattcacgagcgcctcgcgcgctcgatcctcatcctcgac
ggcgccatgggcaccatgatccagcgccaggggctgaccgaggccgattatcgcggcgcg
cgctttgccgattggccgcgcgacctcaagggcaacaatgatctgctggtgctcacccgg
cccgaggtgatcgacggcatccatcgcgcctatctggaggccggcgctgacatcatcgag
accaacagcttcaatgccacccgcatcgccatggccgattacgggatggaggggctcgtc
tacgagatcaatgtcgcggcggctcgactggcgcgcgcggccgccgatgcctacgcgacg
ccggagaaaccgcgtttcgtcgccggggtgctcggaccgaccaatcgcaccgcctcgatc
tcgcccgatgtcaatgacccgggtgcgcgcaacatcgacttcgataccctggtcgcggcc
tatgccgagtcggcgcgcggtctgatcgcaggcggcgccgatctgatcctgatcgagacc
atctttgataccctgaacgccaaggcggcgatctttgcggtcaagcaggtgttcgacgag
gacggggtcgagcgcccgatcatgctctcgggcaccatcaccgatcaatcgggtcggacc
ctgaccggtcagaccaccgaggccttctacaactcactgcgccatgccgagcccctcagc
gtggggctcaactgcgcccttggccccttcgagctgcgccagtatgtcgaggagctggcc
cggatcagtgagtttcatgtctcggcccatcccaacgccggtctgccgaacgcgctcggc
ggttatgacctcggacccgaggtgatggcgaccgagatcgccgagtgggcgcgcgcgggg
ttcctcaacatcgttggcggttgctgtggcaccacgccggatcatatccgcgccatcgcc
gaggccgtggcgggcctgcccccgcgcgtgcggccgaccatcgagcccgcctgccgactg
gcgggtctggaaccgctgaacatcggcccagacaccctgttcgtcaatgtcggcgagcgg
accaatgtcacgggttcggcgcggtttcggcgcctgatcaaggagggcgattacgacacg
gcgctcagcatcgcccaggagcaggtcgacaacggcgcccagatcatcgatgtgaacatg
gacgagggcctgctcgacgccgtggcagcgatgcgccggttcctgaacctgatcgccgcc
gagcccgagatcgcccgggtgccggtgatgatcgattcctccaagtgggaggtgatcgag
accggactcaaatgcgtccagggcaagccgatcgtcaactcgatctcactcaaggagggt
gagcaaaggttcatcgaccaggcgcggctgtgtcggcgctatggtgcagcggtcatcgtc
atggccttcgacgagcagggccaggccgacacccaggcgcgcaaggtcgagatctgtacc
cgggcctaccggctgctgaccgagcgggttggcttcccgcccgaggacatcatcttcgac
cccaacatctttgccgtggccaccggcatcgaggaacacgaccactacgcggtcgatttc
atcgaggccacgcgcgagatcaaacgcaccctgccgcatgccctggtctcggggggggtg
tccaatgtctccttctcctttcgcggcaacgaaccggtgcgccaggcgctccatgccgtc
ttcctctatcacgccatccgggccgggatggatatggggatcgtcaatgccggccagctt
gccatctatgacgagctacccgaggagctgcgcgatgcggtcgaggatgtgatcttaaac
cgccgtccggacgccaccgagcgcctgctcgagctggccccgaggtaccagggtgaaggc
gctggacctgagaacaggtccgatctggaatggcgcacctggccggtcgagaaacggctt
gagcacgcgctggtcaagggtatcgccgacttcatcgatgaggacaccgaggccgcgcgt
cagaccctcgggcgcccgctggcggtgatcgagggcccgctgatgcagggcatggacctc
gtcggcgacctgttcggtgcgggcaagatgttcctgccgcaggtggtgaaatcggcgcgg
gtgatgaagaaggcggtggcctatctccagcccttcctggaggccgagcaggccgagggc
ggcgccgaggcgagcagcaacggcaagttcctgatcgccacggtcaagggcgacgtccac
gacatcggcaagaacatcgtcgccgtggtcttgcagtgcaatggctatgaggtcatcgac
ctcggggtcatggtgccggccgagaccatcctccagcgtgcgcgcgcggtcggtgccgat
gtgatcgggctctcgggtctgatcacgccctcgctcgacgagatggtgcacgtggccaag
gagatgcagcgtcaggggcttgagctgccgctgctgatcggcggtgccaccacctccaaa
ctgcacactgccctcaagatcgccccccagcgcacggccccggtcatctatgtgccggat
gcctcacgggccgtgggcgtggtctccaacctgctgagcgagacccagcgcccaggctat
gtggccgccattgccgaggagtacgagcgcctgcgcgccgagcgcgatgggcgtgcggcg
acccgtaagtcggtgtcgatcctggaggcgcgtgccaatcgcccggcgctcgactgggcg
ggctatgagccgccgcgaccggcactgctcgaccctgagttcagcgagacggccccctgg
tcgctcgcgctggagcgcgccggcgagacggtgatcgccacgctcgctgattttccgctc
gacgacctggtgcacaccatcgactggctccccttctttcgcgcctgggagctggcacac
agccgcttcccggacatcctcgacgacccagtgatcggcgaggaggcgcgcatgctctat
gccgaggcccaggtatttctggaacggctggtggccgagcgctggctccaggcacgcgcg
gtgtttggtttctttcccgccaatgggatcggggacgacgacatcgcactctatgccgac
gcggcgcgcacccagcggctcgcgaccctgcaccacctgcgccagcagatgccacgcgct
ggcggacgccaacaggccaatttctgtctctccgacttcatcgccccagccgagtgcgga
cgccctgactggatcggggcctttgccgtcacggcgggggtggggatcgaggggcctctg
gcgcggttcgtggccgatcaggatgactacagcgcgatcctgctcaaggcgctcgccgac
cggctggccgaatcattcgccgagcggctgcaccaactggtgcgcacccgctattggggc
tatgcgacggatgagcagctcagcaacgaagagctcattgccgagcattatcggggcatc
cgaccagcgcccggctatgccgcctgcccggatcacaccgagaaggggacgctctggagg
ctgctcgaacccgaccggcgcatcggtcttatcctcaccgaaaactttgccatgctgccg
gcggcgtcagtctcgggctggtacttcgcccaccccgaggcgcgctatttcggtgtgggg
cgcatccagcgcgatcaggtcgaggactatgcccagcgcaagggttggaccctggatgag
gccgagcgctggctggcgccggtgctgggctatgagccctga

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