Thermus thermophilus SG0.5JP17-16: Ththe16_0206
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Entry
Ththe16_0206 CDS
T01867
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
tts
Thermus thermophilus SG0.5JP17-16
Pathway
tts00010
Glycolysis / Gluconeogenesis
tts00020
Citrate cycle (TCA cycle)
tts00620
Pyruvate metabolism
tts00785
Lipoic acid metabolism
tts01100
Metabolic pathways
tts01110
Biosynthesis of secondary metabolites
tts01120
Microbial metabolism in diverse environments
tts01200
Carbon metabolism
tts01210
2-Oxocarboxylic acid metabolism
Module
tts_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
tts00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Ththe16_0206
00020 Citrate cycle (TCA cycle)
Ththe16_0206
00620 Pyruvate metabolism
Ththe16_0206
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Ththe16_0206
Enzymes [BR:
tts01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Ththe16_0206
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
AEG32639
UniProt:
F6DIB3
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All DBs
Position
190619..193336
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AA seq
905 aa
AA seq
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MTEKELKAAFQALSPEEKARFLEIENREWLESLEYVLKVEGPERVEELLRLLDEYLFRHG
VYPANRLSTPYLNTLPKEKEPPYPGDLELERRIANILRWNVAMMVTRANKKADGIGGHIA
TYASIAELYEVGFNHFFRGPEAGLDRDLVFFQGHASPGNYARAFLEGRLKEEDLENFRRE
VHPPVPGGRGLSSYPHPWLMPDFWEFPTVSMGFGPIQAIYQARFMRYLEDRGLKPKSSAK
VWAFLGDGEHDEPETVGALHLAAREGLDNLIFVVNCNLQRLDGPVRGNSKVIQELERLYR
GAGWHVIKVVWGSAWDELLAKDKEGHLLRRFEALVDGESQRYAAFGGKELRERFFNTPEL
KKLIEGMTDEELTELTRSRGGHDLVKIYAAYKAAVEHKGSPVVILACTIKGYGMGPSVMA
KNVAHQVKKLTEEDLKEARRFLGIPVPEEKLEELPYYHPGPDSPEVKYLLERRKALGGFV
PERRVRFKGGLEVPDEAFFREFYEGSGGREISTTMAFVRILAKLLRHPAVGKYIVPIVPD
EARTFGMEALIAQVGIYSPQGQLYIPVDAGTLTAYKESREGQILEEGITEAGAMADFIAA
GTAYAHWGIPTIPFLITYSMFGLQRIGDLVWAAADQRTRGFFLGATAGRTTLAGEGLQHQ
DGQSHVYALAAPNLLAYDPAFAYEFAVILEDGLRRMYGKGEDVFYYITIENENYVHPPMP
EPREKVKEGILKGLYLFRAGEGKGPKVQLFGTGPILNEALKAQELLAQYGVVAEVWSATS
YKALYYDAIEAEREARLLGKPRKPYVVEALEGHEGPIVAATDYLKALPNLIRGYLDRPFA
VLGTDGFGRSDTREALRDFFEVDARHIAYTALALLHGEGKVTKRTLNQARKDLGLKLEEV
PPHRR
NT seq
2718 nt
NT seq
+upstream
nt +downstream
nt
atgacggaaaaggagctgaaggcggccttccaggccctttcgcccgaggagaaggcccgc
ttcctagaaatagagaaccgggagtggctggagtctttggagtacgtcctcaaggtggag
ggccccgagcgggtggaagagctcttgcgccttctggacgagtacctcttccgccatggg
gtttaccccgcaaaccgcctctccaccccctacctcaacacccttcccaaggagaaggag
cccccttaccccggggacctggagctggagcgccgcatcgccaacatcctccgctggaac
gtggccatgatggtcacgcgggccaacaagaaggcggacggcatcggggggcacatcgcc
acctacgcctccatcgccgagctttacgaggtgggcttcaaccacttcttccgggggccg
gaggcggggctggaccgggacctggtcttcttccaggggcacgcctcccccgggaactac
gcccgggccttcctggagggaaggcttaaggaggaggatttagagaacttccgccgcgag
gtccacccgcccgtgcccgggggccgggggctttccagctacccccacccctggctcatg
cccgacttctgggagttccccacggtctccatgggctttggccccatccaggccatctac
caggcccgcttcatgcgctacctcgaggaccgaggcctcaagcccaaaagctccgccaag
gtctgggccttcctgggggacggggagcacgacgagcccgagaccgtgggcgccctgcat
ctggcggcccgggaggggctggacaacctcatcttcgtcgtgaactgcaacctccagcgc
ctggacggccccgtgcggggcaactccaaggtcatccaggagctggagaggctctatagg
ggcgcgggctggcacgtgatcaaggtggtctggggctcggcctgggacgagctcctcgcc
aaggataaggagggccacctcctccgccgctttgaggccctggtggacggggaaagccag
cgctacgccgccttcggggggaaggagcttagggagcgcttcttcaacacccccgagctt
aagaagctcattgaggggatgacggacgaggagctcaccgagctcacccgctcccggggc
ggccacgacctggtcaagatctacgccgcctacaaggccgcggtggagcacaaggggagc
cccgtggttatcctggcctgcaccatcaagggctacggcatggggccctcggtcatggcc
aaaaacgtggcccaccaggtgaagaagctcaccgaggaggacctgaaggaggcgaggcgc
ttcctagggattcccgtccccgaggagaagctggaggagcttccctattaccacccgggg
ccggactccccggaggtcaagtacctcctggaaaggaggaaggccctcgggggcttcgtg
cccgaaaggagggtgcgcttcaaggggggcctcgaggttccggacgaggcgttcttccgg
gagttctacgagggctcgggggggcgggagatctccaccaccatggccttcgtgcgcatc
ctggccaagctcctccgtcaccccgccgtgggcaagtacatcgtccccatcgtccccgac
gaggcccgtaccttcggcatggaggccctcatcgcccaggtgggcatctactcccctcag
gggcagctctacatccccgtggacgccgggaccctcaccgcctacaaggagagccgggag
ggccagatcctggaggaggggatcacggaggccggggccatggccgacttcatcgctgcc
ggcaccgcctacgcccactggggcatccccaccatccccttcctcatcacctactccatg
ttcggcctgcaacgcatcggggacctggtctgggccgctgccgaccagcgcacccggggc
ttcttcctcggggccacggcggggcgcaccaccctggcgggggagggccttcagcaccag
gacggccaaagccacgtctacgccctggccgcccccaacctcctcgcctacgaccccgct
ttcgcctacgagttcgccgtgatcctggaggacggcctccgccgcatgtacggcaagggg
gaggacgtcttctactacatcaccattgagaacgagaactacgtccacccccccatgccc
gagccccgggaaaaggtcaaggaggggatcctaaaagggctttacctcttccgggcgggg
gaggggaagggcccgaaggtgcagcttttcggcaccgggcccatcctcaacgaggccctg
aaggcccaggagctattggcccagtacggcgtggtggccgaggtctggagcgccaccagc
tacaaggccctctactacgacgccatcgaggcggagcgggaggcccgccttttgggcaag
ccccggaagccctacgtggtggaggccctcgagggccacgagggccccatcgtggccgcc
accgactacctcaaggccctgcccaacctcatccggggctacctggaccggcccttcgcc
gtcttgggcaccgacggcttcggccgctccgacacccgggaggccttaagggacttcttt
gaggtggatgcccggcacatcgcctacaccgccttggccctgctccacggggagggcaag
gtgacgaagaggaccctgaaccaggcgcggaaggaccttggccttaagctggaggaggtg
ccgccccaccggcgctag
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