KEGG   Thunnus thynnus (Atlantic bluefin tuna): 137171222
Entry
137171222         CDS       T11154                                 
Symbol
pik3r1
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1
  KO
K02649  phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
tty  Thunnus thynnus (Atlantic bluefin tuna)
Pathway
tty04012  ErbB signaling pathway
tty04068  FoxO signaling pathway
tty04070  Phosphatidylinositol signaling system
tty04081  Hormone signaling
tty04140  Autophagy - animal
tty04150  mTOR signaling pathway
tty04210  Apoptosis
tty04218  Cellular senescence
tty04370  VEGF signaling pathway
tty04510  Focal adhesion
tty04620  Toll-like receptor signaling pathway
tty04625  C-type lectin receptor signaling pathway
tty04810  Regulation of actin cytoskeleton
tty04910  Insulin signaling pathway
tty04914  Progesterone-mediated oocyte maturation
tty05100  Bacterial invasion of epithelial cells
tty05168  Herpes simplex virus 1 infection
Brite
KEGG Orthology (KO) [BR:tty00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    137171222 (pik3r1)
   04370 VEGF signaling pathway
    137171222 (pik3r1)
   04068 FoxO signaling pathway
    137171222 (pik3r1)
   04070 Phosphatidylinositol signaling system
    137171222 (pik3r1)
   04150 mTOR signaling pathway
    137171222 (pik3r1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    137171222 (pik3r1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    137171222 (pik3r1)
  09143 Cell growth and death
   04210 Apoptosis
    137171222 (pik3r1)
   04218 Cellular senescence
    137171222 (pik3r1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    137171222 (pik3r1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    137171222 (pik3r1)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    137171222 (pik3r1)
   04625 C-type lectin receptor signaling pathway
    137171222 (pik3r1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    137171222 (pik3r1)
   04914 Progesterone-mediated oocyte maturation
    137171222 (pik3r1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    137171222 (pik3r1)
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    137171222 (pik3r1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tty04131]
    137171222 (pik3r1)
Membrane trafficking [BR:tty04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    137171222 (pik3r1)
SSDB
Motif
Pfam: PI3K_P85_iSH2 SH2 RhoGAP SH2_1 SH3_1 AAA_13 SH3_9 Laminin_I SH3_2 PI_PP_I
Other DBs
NCBI-GeneID: 137171222
NCBI-ProteinID: XP_067431171
LinkDB
Position
19:complement(7156355..7187516)
AA seq 740 aa
MSAEGYQYRALYDYKKEREEDIDLRVGDILLVSKGALVALGYTDGLEQRPDEIGWLPGFN
ETTQEKGDFPGTYVEYIGKKWISPPTPKPRPLRPLPVAPGSFKAETDSDSEQGEFNTGPQ
KCITGFCLLDLTEQFSLPETSPPMLARLLEAIEKKGLDNPTLYRTFTAGGGLEVRQYFDC
DPPSADLDQLELPILCDGLRRYLQDLPQPIIPTAIYAQMVHTAKEVVNPEECAQLLRRIA
SNPSLPSQYWLTLHCLLRHFARVCQNGSKNLLSARALGEIFSPVFFRQQASSCEPSLDAH
IKIIEVLVTSEWSESQAAPALPPKPPKPTSVSNNGMNNSMALQDAEWYWGDISREEVNEK
LRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELIN
HYRNESLAQYNPKLDVKLLYPVSKHQQDQVVKEDNIEAVGRKLCEYHQQYQEKNKEYDRL
YEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFRREGNDKEIQRIMG
NYEKLKSRISEIVDSKRRLEEDLKKQAADYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQ
KGVRQKKLNEWLGIKNENTEDQYSMVDDDEDLPHHDERSWKLGNINRLQAEALLQGKRDG
TFLVRDSSKAGCYACSVVVDGEVKHCVINKTPSGYGFAEPYNLYGSLKELVLHYQHTSLV
QHNDSLNVTLAYPVYAQQRR
NT seq 2223 nt   +upstreamnt  +downstreamnt
atgagtgctgaaggatatcaatacagggcgctttatgactacaagaaggagagggaggag
gacattgatctgcgtgtgggggatatactgttggtaagcaaaggggcactggtggccctt
gggtacactgatgggctggaacagaggccagatgagattggctggctgcccggcttcaac
gaaaccactcaggaaaaaggggacttccctgggacatatgtcgagtacattggaaagaaa
tggatctctccccccacgcccaagccacggcccctcagacccttacctgtagctccaggc
tccttcaaggcggagacagactcggactcggagcaaggtgagttcaacaccggaccacag
aagtgtataacaggcttctgtctgctggacttgacggagcagttttcccttccagagaca
tctccgcccatgctagccagactgctggaagctattgagaagaaaggtctggataacccc
acattatatcggacatttactgctggtggtggacttgaagtcagacaatattttgattgt
gatcctccctcagcagacttggatcaattggaacttccgatcctgtgtgatggtctgcgt
aggtacctgcaggatcttccccagcccatcatccccactgcaatatatgctcaaatggtc
cacactgccaaagaggtggtgaatcctgaagaatgtgcccagctgctacgtcgcattgcc
agcaacccgagcctgccttcacaatactggctaaccctccactgtctgctaaggcatttc
gctagggtgtgccaaaacggctctaagaacttgctctctgccagagcgctgggcgagatc
tttagccctgtgtttttcagacaacaggccagcagttgtgaacccagcttggacgctcac
atcaagatcattgaggttctggtgaccagtgaatggagtgaaagtcaggcagctccagct
ctacctccaaagccacccaagcccacatctgtgagtaacaacggtatgaacaacagcatg
gctctacaagacgctgaatggtactggggagacatctcaagggaggaggtcaatgaaaaa
ctgagggacactgcggacggtacgtttttggtgcgagacgcctctacaaaaatgcacggc
gactacaccctgactctgaggaaaggaggaaacaacaaactcattaagatattccaccgg
gatgggaagtacggcttctcagaccctctgaccttcagctccgtcgttgagctcatcaac
cactatcgcaacgagtcactggctcagtacaaccccaagctagacgtcaaactgctgtac
ccggtctccaaacaccagcaggatcaggtggtgaaagaagacaacatcgaagcggtgggg
aggaaactctgtgagtaccaccagcagtaccaggagaagaacaaagagtacgaccgtctg
tatgaagaatacaccagaacatcacaagaaatccaaatgaaaaggacagctattgaggct
tttaatgaaactataaagatctttgaggagcaatgccaaacacaagagcggtacagcaaa
gagtatatcgagaagttcagaagagaaggcaacgacaaggagatccagaggattatgggc
aactacgagaagttgaaatccaggataagtgaaatcgtagacagcaagcgtcgactggag
gaagatctgaagaaacaagcggcagactacagagagatcgacaagaggatgaacagcatc
aagcctgacctcatccagctccgcaagaccagagaccagtatctcatgtggttgactcag
aagggagtcagacagaagaaactcaacgagtggctgggaatcaagaacgagaacacagaa
gatcaatattctatggtggacgatgatgaagatcttcctcatcacgatgaacggtcctgg
aagttgggcaacatcaaccgactacaggcggaggctctcctccagggcaagagagacgga
acattcctggttcgagacagcagcaaagcaggatgctacgcctgcagcgttgtcgtggac
ggtgaggtgaagcactgcgtcatcaacaagaccccctcaggttatggcttcgccgagccg
tacaacctgtacggctcgttaaaagaactcgtacttcactaccagcacacgtctttggtc
cagcacaatgactctctgaatgtgacgctagcgtaccctgtttatgcccagcagagacgg
tga

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