Thunnus thynnus (Atlantic bluefin tuna): 137181226
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Entry
137181226 CDS
T11154
Symbol
itcha
Name
(RefSeq) itchy E3 ubiquitin protein ligase a isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
tty Thunnus thynnus (Atlantic bluefin tuna)
Pathway
tty04120
Ubiquitin mediated proteolysis
tty04144
Endocytosis
tty04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
tty00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
137181226 (itcha)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
137181226 (itcha)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
137181226 (itcha)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tty04131
]
137181226 (itcha)
04121 Ubiquitin system [BR:
tty04121
]
137181226 (itcha)
Enzymes [BR:
tty01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
137181226 (itcha)
Membrane trafficking [BR:
tty04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
137181226 (itcha)
Ubiquitin system [BR:
tty04121
]
Ubiquitin ligases (E3)
HECT type E3
137181226 (itcha)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
137181226
NCBI-ProteinID:
XP_067442881
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Position
4:12975392..12990990
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AA seq
882 aa
AA seq
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MKAQLQVTVLSAKLKENKKNWFGPSPYVEVAVDGQSKRTEKCNNTHSPKWKQAVTVIVTP
VSKLIFRVWSHQTLKADILLGMATLEISETLKANDLKLCEVVQTLQLSSDRDSRDIVGDL
SVCLDGMQVDPETFASAERNHASVPNGKARQNGDTGKRASIDMSPSSDSDEWVIVPNGHA
VNGTGSPSRSPGGSTALRPPRPARPPPPTPRRPAASPTSSSSSTPSELSEGPATDGSSQA
SASGCSDQQDDSGAGAGAGAGAGAGAGAGAATASSSQTTSVPKPGASASAAPAAAAPRIT
PMNNGPLPPGWEQRVDQNGRMYYVDHIEKRTTWERPDPLPTGWERRVDPMGRVYYVDHMT
RTTTWQRPTQESVRNYEEWQHQRSQLQGAMQQFNQRFIYGLQDQLAATANKEFDPMGPLP
HGWEKRTDTNGRVYFVHHPTRTTQWEDPRTQGLLNDKPLPEGWEMRFTVDGIPYFVDHNR
RTTTYIDPRTGKSSLENGPQITYVRDFKAKVQYFRFWCQQLSMPQHIKITVSRKTLFEDS
FQQIMSFHPQDLRRRLWIIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYC
LQINPASYINPDHLKYFKFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPLALKDLESID
PEFYNSLIWIKDNNIEECGLEMFFSVDKEILGEVTTHELKPDGGNVQVTEENKEEYIRLV
AEWRLSRGVEEQTQAFFEGFNEVLPQQYLQYFDAKELEVMLCGMQEIDLVDWQRNTIYRH
YARSSKQILWFWQFVKEMDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGK
ENWLPRSHTCFNRLDLPPYKSYEQLKEKLMFAIEETEGFGQE
NT seq
2649 nt
NT seq
+upstream
nt +downstream
nt
atgaaggcccaattgcaagtcacagtgctttcagccaagctgaaggaaaacaaaaagaac
tggtttggtcccagtccatatgttgaggtagctgtggatggccagtcaaagagaactgag
aaatgcaacaacacgcatagtcctaaatggaagcaggctgtcactgtaattgtgactcct
gtcagcaagctgatctttcgtgtttggagccaccagacactgaaggcagacatcctacta
ggaatggccacactggagatcagtgagacccttaaggctaatgatctgaaattgtgtgag
gtggtgcagacactgcagctgtcctctgacagagactcccgggatattgtaggtgacctg
tcagtctgcttggatggcatgcaggtggacccagaaacctttgcctcggcagagagaaat
catgcttctgttccaaatggaaaggccagacaaaatggagacactggcaaaagggccagc
atagacatgtctccctccagtgactcagacgagtgggtcattgtacctaatggtcatgct
gtgaacggtacaggctctccttcccggtctccagggggctccaccgctttacgtccccct
agacctgctcgcccgccacctcctacaccccgtagacctgcagcctcaccaacttcttct
agcagttctactcccagtgagctgagcgaaggcccagctaccgatggctcctctcaggca
tctgcaagcgggtgttcagatcagcaagatgactctggtgcaggtgccggtgcaggtgca
ggtgcaggtgcaggtgcaggtgcaggagcagcaacagcgagttcctcacagacaacaagt
gtccccaaaccaggggcctctgcctcagcagctccagccgcagctgctcctagaatcaca
cccatgaacaacggtcccttgccaccagggtgggagcaaagggtggaccaaaatggacgt
atgtactacgtggatcacattgagaagagaacaacctgggagaggcctgaccctctgcct
acagggtgggagcgcagggtggacccgatgggtagggtgtactatgtcgaccacatgacc
cgaactaccacgtggcaacgccccacgcaggagtcagtgcgtaattatgaggagtggcag
caccagcgtagccagctgcagggagccatgcagcagtttaaccagaggttcatttatggg
ctccaagaccagctggcagccacagccaataaagagtttgacccaatgggacctttgccg
catggttgggagaagagaacagacaccaacggcagagtgtattttgttcatcacccgact
cgaacgacacagtgggaagaccccaggacgcaagggttgctgaatgacaagcctctgcca
gagggctgggagatgaggttcacggtggatggtattccctactttgtagaccacaacaga
cgaaccacgacctacattgaccctcgcacaggaaaatcctcgcttgagaatggaccacag
ataacctacgtcagggacttcaaagccaaagtgcaatacttcagattctggtgtcagcaa
ttgtcgatgcctcagcacattaagattaccgtctccaggaaaaccttgtttgaggattca
ttccaacagatcatgagcttccaccctcaagatctgaggcggagactttggattattttc
cctggagaggaaggcttggactacggaggcgtggccagggaatggttcttcttgctttct
catgaggtactgaaccccatgtactgtttattcgagtatgctggcaaggacaactactgc
ctgcaaatcaaccctgcctcctacatcaaccctgatcacctcaagtacttcaagttcatc
gggcgcttcattgccatggccttgttccacggcaaattcatcgacacaggtttctccctg
cccttctacaagcgtatcctgaacaaacctctggctctcaaagacctggagtccatagat
ccagagttttacaactctctcatctggatcaaggacaataacatagaggagtgtggtctg
gagatgttcttctcagtagacaaggagatcctgggggaggtcaccacccacgagctgaaa
ccagacggagggaacgttcaagtaactgaggaaaataaggaggaatacatcaggttagtt
gcagagtggaggctgtccagaggtgtggaggagcagactcaggctttctttgagggcttc
aatgaagttctgccccagcagtaccttcagtactttgatgctaaggaattagaggtgatg
ctgtgcgggatgcaagagatagacctagtggactggcagagaaacaccatctacagacat
tatgcccgaagtagcaagcagatcctttggttctggcagtttgtaaaggagatggacaac
gagaagaggatgagactgctgcagtttgtcacaggaacttgtcgtcttcctgtgggtggc
ttcgctgacctgatgggaagcaacggcccccaaaagttctgcattgagaaagtgggcaaa
gagaactggcttccacgaagccacacatgctttaatcgtctggaccttcctccttacaag
agctatgagcagctgaaggagaaactcatgttcgccatagaggagacagagggctttggg
caggagtaa
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