KEGG   Tumebacillus avium: CBW65_02730
Entry
CBW65_02730       CDS       T04874                                 
Name
(GenBank) bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
tum  Tumebacillus avium
Pathway
tum00270  Cysteine and methionine metabolism
tum00450  Selenocompound metabolism
tum00670  One carbon pool by folate
tum01100  Metabolic pathways
tum01110  Biosynthesis of secondary metabolites
tum01120  Microbial metabolism in diverse environments
tum01230  Biosynthesis of amino acids
Module
tum_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:tum00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    CBW65_02730
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    CBW65_02730
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CBW65_02730
Enzymes [BR:tum01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     CBW65_02730
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     CBW65_02730
SSDB
Motif
Pfam: S-methyl_trans MTHFR PEP_mutase
Other DBs
NCBI-ProteinID: ARU60090
UniProt: A0A1Y0IIG5
LinkDB
Position
complement(538949..540937)
AA seq 662 aa
MPKKRRFLLYSDFIPLSEHYYIEALRQREGGCSVSSRHELFRQKLGTDVLIGDGAMATWL
YQQGHAVGSSTEELCLKNQEWVREAHMAYLRAGAQVIETNSYAANREALARYGLERKTTR
INRAAVQLARQAVEIAEADAFVVGSIGSIAAARVMTANVEEFRDSFEEQAVALLHEGVDG
LVLETFFDLEELLLALDVVRPLVASSGVPIIAQCSLLDVERTRDGYLLSDAYFKLKEAGA
DMVGLNCRLGPAEILRALERAVVPEGLGLSAFPNAGRPAIVDGEFAYKPNYQYFGDSAVK
LWEQGVSLIGGCCGTTPEHIQAIAGAVSGLKRRPRVNPENAPRIEVFEREVVRFQQSEMP
TIVDLVEKRHTIIVEFDSPRDLDVERYVEGSHELYKAGADAITIADNSLATTRMSNMALG
SIIKRELGIEPVVHVACRDRNLIGQQSHLMGLHALGINQILVITGDPARVGDLPGASTVF
DLTSFDLIRMVKQLNQGVAFSGRPMKNQARFVCGAAFNPHVRNLDAAVARLERKVEAGAD
YIMTQPVYDLETMLAIKEATAHIKVPIFIGIMPLTSTRNAEFLHNEVPGIKISQKSRERI
KRFEGAAARAEGVEMCKELLDEAVKHYNGIYLITPFNYFEMTVELTKHVREITQVTSRAS
TF
NT seq 1989 nt   +upstreamnt  +downstreamnt
atgccaaagaagaggcgttttcttttatattcggactttattccgttatcggagcactac
tacatcgaagcactacgacaaagagagggaggatgcagcgtgagcagtcggcatgagttg
tttcggcaaaaacttggcacagacgtgctgatcggcgacggcgcgatggcgacgtggctg
taccagcaaggccatgcggtcggctcttcaaccgaggagttgtgtttgaaaaatcaagag
tgggtgcgcgaagcccacatggcgtacttgcgtgcaggagcgcaggtgatcgagaccaac
tcctacgcggcgaaccgcgaagcgctcgcccgctacgggctggagcgcaagacgacgcgg
atcaaccgcgcggctgtacagcttgcccgccaggcggtggagatcgccgaagcggatgcg
tttgtcgtcggcagcatcggctcgatcgcggcggcccgcgtgatgaccgccaatgtcgaa
gagttccgcgactcttttgaggaacaggcggtggcgttgcttcacgaaggcgtggacggt
ctggtgctggagacgttcttcgatctggaagaactgctcctcgcgctcgacgtggtgcgt
ccgctcgtcgcatcctccggtgtgccgatcatcgcccagtgctcgctgctcgatgtcgag
cgcacccgggacggctacctgctcagcgatgcgtattttaaattgaaagaagcgggcgcc
gacatggttggcctgaactgccgcctcggtccggccgagatcttgcgggcgctggagcgg
gcggtggtgccggaagggctgggcttgtcggcgttcccgaacgcaggccgcccggcgatc
gtcgacggagagtttgcctataagcccaattatcagtattttggagatagtgcggtcaaa
ctgtgggagcaaggcgtatcgctgatcggcggctgctgcggcacaacgccggagcatatc
caggcgatcgcaggcgccgtgtccggcctgaagcgccgcccgcgtgtcaacccggagaac
gccccgcgcatcgaagtgtttgagcgcgaagtggtgcgcttccagcagagcgagatgccg
accatcgtcgacctcgtggagaaacggcacacgatcatcgtcgagttcgactcgccgcgc
gatctggatgtggagcgctatgtcgaaggctcccatgagctgtacaaggcgggggcggac
gcgatcaccatcgccgacaactcgctggcgaccacgcggatgagcaacatggcgcttggc
tcgatcatcaaacgggagctgggcatcgagccggtcgtgcacgtcgcctgccgcgaccgc
aacctgatcgggcagcagtcgcacctgatggggctgcatgcgctgggcatcaatcagatc
ctcgtcatcaccggcgatccggcccgcgtcggcgacctgccgggggcgagcaccgtgttt
gacctgacgtcgttcgatctgatccgcatggtcaaacagttgaaccaaggcgtcgccttc
tccgggcgtccgatgaagaatcaggcccgcttcgtctgcggcgcagcgttcaacccgcat
gtgcgcaacctcgacgcggcggtcgcccgcctcgaacgcaaagtcgaagcgggggcggac
tacatcatgacccagccggtgtacgatctggaaacgatgctggcgatcaaagaagcgacc
gcgcatatcaaagtcccgatcttcatcggcatcatgcctttgacctcgacgcgcaacgcc
gagtttctgcacaacgaagtgccaggcatcaagatttcgcaaaagtcccgcgagcggatc
aagcgcttcgaaggcgcggctgcacgggcagaaggcgtcgagatgtgcaaagagctgctc
gatgaagcggtcaaacattataacggcatctatctgatcacgccgttcaattatttcgaa
atgacggtcgaactgaccaaacacgtccgcgagatcacacaggtcaccagccgggcaagc
actttttaa

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