Tupaia chinensis (Chinese tree shrew): 102468873 Help Entry 102468873         CDS       T02978                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup00230   Purine metabolism tup01100   Metabolic pathways tup01522   Endocrine resistance tup04015   Rap1 signaling pathway tup04020   Calcium signaling pathway tup04022   cGMP-PKG signaling pathway tup04024   cAMP signaling pathway tup04062   Chemokine signaling pathway tup04072   Phospholipase D signaling pathway tup04081   Hormone signaling tup04082   Neuroactive ligand signaling tup04114   Oocyte meiosis tup04211   Longevity regulating pathway tup04213   Longevity regulating pathway - multiple species tup04261   Adrenergic signaling in cardiomyocytes tup04270   Vascular smooth muscle contraction tup04371   Apelin signaling pathway tup04540   Gap junction tup04611   Platelet activation tup04713   Circadian entrainment tup04714   Thermogenesis tup04720   Long-term potentiation tup04723   Retrograde endocannabinoid signaling tup04724   Glutamatergic synapse tup04725   Cholinergic synapse tup04727   GABAergic synapse tup04750   Inflammatory mediator regulation of TRP channels tup04911   Insulin secretion tup04912   GnRH signaling pathway tup04913   Ovarian steroidogenesis tup04914   Progesterone-mediated oocyte maturation tup04915   Estrogen signaling pathway tup04916   Melanogenesis tup04918   Thyroid hormone synthesis tup04921   Oxytocin signaling pathway tup04923   Regulation of lipolysis in adipocytes tup04925   Aldosterone synthesis and secretion tup04926   Relaxin signaling pathway tup04927   Cortisol synthesis and secretion tup04928   Parathyroid hormone synthesis, secretion and action tup04934   Cushing syndrome tup04935   Growth hormone synthesis, secretion and action tup04970   Salivary secretion tup04971   Gastric acid secretion tup04972   Pancreatic secretion tup04976   Bile secretion tup05032   Morphine addiction tup05142   Chagas disease tup05146   Amoebiasis tup05163   Human cytomegalovirus infection tup05166   Human T-cell leukemia virus 1 infection tup05200   Pathways in cancer tup05207   Chemical carcinogenesis - receptor activation tup05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:tup00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102468873 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102468873 (ADCY1)    04371 Apelin signaling pathway     102468873 (ADCY1)    04020 Calcium signaling pathway     102468873 (ADCY1)    04072 Phospholipase D signaling pathway     102468873 (ADCY1)    04024 cAMP signaling pathway     102468873 (ADCY1)    04022 cGMP-PKG signaling pathway     102468873 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102468873 (ADCY1)    04081 Hormone signaling     102468873 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102468873 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     102468873 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102468873 (ADCY1)    04062 Chemokine signaling pathway     102468873 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     102468873 (ADCY1)    04923 Regulation of lipolysis in adipocytes     102468873 (ADCY1)    04912 GnRH signaling pathway     102468873 (ADCY1)    04913 Ovarian steroidogenesis     102468873 (ADCY1)    04915 Estrogen signaling pathway     102468873 (ADCY1)    04914 Progesterone-mediated oocyte maturation     102468873 (ADCY1)    04921 Oxytocin signaling pathway     102468873 (ADCY1)    04926 Relaxin signaling pathway     102468873 (ADCY1)    04935 Growth hormone synthesis, secretion and action     102468873 (ADCY1)    04918 Thyroid hormone synthesis     102468873 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     102468873 (ADCY1)    04916 Melanogenesis     102468873 (ADCY1)    04925 Aldosterone synthesis and secretion     102468873 (ADCY1)    04927 Cortisol synthesis and secretion     102468873 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102468873 (ADCY1)    04270 Vascular smooth muscle contraction     102468873 (ADCY1)   09154 Digestive system    04970 Salivary secretion     102468873 (ADCY1)    04971 Gastric acid secretion     102468873 (ADCY1)    04972 Pancreatic secretion     102468873 (ADCY1)    04976 Bile secretion     102468873 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     102468873 (ADCY1)    04727 GABAergic synapse     102468873 (ADCY1)    04725 Cholinergic synapse     102468873 (ADCY1)    04720 Long-term potentiation     102468873 (ADCY1)    04723 Retrograde endocannabinoid signaling     102468873 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102468873 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     102468873 (ADCY1)    04213 Longevity regulating pathway - multiple species     102468873 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     102468873 (ADCY1)    04714 Thermogenesis     102468873 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102468873 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     102468873 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102468873 (ADCY1)    05163 Human cytomegalovirus infection     102468873 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     102468873 (ADCY1)    05142 Chagas disease     102468873 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     102468873 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102468873 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102468873 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102468873 (ADCY1) Enzymes [BR:tup01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102468873 (ADCY1) SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6688 DUF6594 Motif Other DBs NCBI-GeneID:  102468873 NCBI-ProteinID:  XP_006166099 LinkDB All DBs Position Un AA seq 842 aa AA seqDB search MYGVFVRILTERSQRKAFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGYGHERNSF LKTHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS NVMTCEDDDKRRALRTASEKLRNRSSFSANVVQTTPGTRVNRYLSRLLEARQPELELADL NFFTLKYKHAEREQKYHQLQDEYFTSAVVLALILAALFGLVYLLVIPQSLAVLLLLVFCI CFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWGWSPKSNI SLAVISSGSRHPVLPALPCESTHHALLCCLVGTLPLAIFLRVSSVPKMILLSGLTTSYIL VLELSGYTKAGGGASSGRSYEPILAILLFSCALALHARQVDVRLRLDYLWAAQAEEERDD MERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELD GNNMGVECLRLLNEIIADFDELMEKDFYKDLEKIKTIGSTYMAAVGLAPTVGTKAKKSIS SHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNV ASRMDSTGVQGRIQLYSKDGALALVFKQQPARLPRSAGKVLGWSRMGTALIQSLWPMFHD RQ NT seq 2529 nt NT seq  +upstreamnt  +downstreamnt atgtacggcgtcttcgtgcggatccttaccgagcgctcgcagaggaaggcattcctacag gcccggagctgcattgaggaccggctgcgactggaggatgagaacgagaagcaggagcgg ctcctcatgagcctcctgccccggaacgttgccatggagatgaaggaggacttcctcaag cccccggagaggattttccacaagatttacatccagaggcacgacaatgtgagcatcctg tttgcagacatcgttggcttcacaggcttggcatcccagtgcacagcccaggagctggtg aaactcctcaatgagctctttggaaagttcgacgagttagccacggagaaccactgtcgt cgcatcaagatcctgggggattgttactactgcgtgtcaggtctcacccagcccaagact gaccacgcccactgctgcgtggagatggggcttgacatgatcgacaccatcacgtctgtg gccgaggccactgaggtggacctgaacatgcgcgtggggctgcacaccggtcgggtcctc tgtggtgtcctgggcctgcgcaagtggcaatacgatgtgtggtccaacgacgtgacccta gccaatgtcatggaagccgctggcctgccagggaaggttcacatcacaaagacaacctta gcgtgcctgaatggagactatgaggtggagccgggttatggacatgagaggaacagtttc ttgaaaactcacaacattgagacctttttcattgtgccatcccatcggcggaagatattt ccaggcctgattctgtcggatatcaagcctgccaagaggatgaagttcaagactgtgtgc tacctgctggtgcagctcatgcactgccggaagatgttcaaggctgagatccccttctcc aatgtcatgacctgtgaggatgatgacaagcggagggcactgagaactgcctcggagaaa ctcagaaaccgctcatccttctctgcgaatgtggtccaaaccacgcccggcacgcgtgtc aacaggtacctcagccgcctcttggaagcccgccagccggagctggagcttgctgatctg aacttcttcaccctgaagtacaaacatgccgagcgggagcaaaagtaccaccagcttcag gacgagtatttcaccagcgccgtcgtcctcgccctcatcctggctgccttattcggcctt gtctaccttctggtaatcccacagagcctggccgtcctgctcctgctagtgttctgcatc tgcttcctggtggcgtgtgtcctgtacctgcacatcactcgggtccagtgttttccaggg tgcctgacgattcagattcgcaccgtgctgtgtattttcatcgtggtcttaatctactca gtagcccaaggttgtgtggtgggctgcctcccctggggttggagccccaagtccaacatt tccctggcggtcatctcgtctgggagccgacaccctgtgctgcctgctctgccctgtgag tccacgcaccatgccctgctctgctgcctggtgggcaccctcccgctcgccatcttcctg cgggtgtcctctgtgccaaaaatgatcctgctgtctgggctcaccacgtcttacatcctg gtcctggagctcagcgggtacaccaaggctgggggcggcgccagctcgggacgcagctat gagcccatcctggccattctgctgttctcgtgtgcactggccctgcacgcacggcaggtg gacgtcaggctgcggttggactacctctgggccgcgcaggcagaagaggagcgagatgac atggagagagtgaagctggacaacaagcggatcctcttcaacctcctgccagcccacgtg gcccagcacttcctcatgtccaatccccggaacatggacctttactaccagtcctactcc caggtgggtgtcatgttcgcctccatcccgaacttcaatgacttctacattgagctggat ggcaacaacatgggtgtggagtgtctgcggcttcttaatgagatcatcgctgacttcgat gagctcatggagaaagacttttacaaggacctagagaagatcaagaccattgggagcacc tacatggctgcagtgggactggcgcccacagtggggaccaaggctaagaagtctatctcc tcccacctgagcacgctggccgactttgccattgagatgtttgacgtcctggatgagatc aactaccagtcttataacgacttcgtcctccgtgttggcatcaacgtcggccccgtggtg gctggggtgattggcgcgcgcaggccgcagtacgacatctgggggaacacggtcaatgtg gctagtcgaatggacagcaccggcgtccagggcagaatccagctttactctaaagatgga gcattggccctagtgttcaagcagcaacctgcaaggctgcctcgttcggctggaaaggtc ttaggctggtcgcgcatggggacagcactgattcagtctctgtggccaatgtttcatgat cggcagtga

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