Tupaia chinensis (Chinese tree shrew): 102471949 Help Entry 102471949         CDS       T02978                                  Symbol JAK3 Name (RefSeq) Janus kinase 3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup04062   Chemokine signaling pathway tup04151   PI3K-Akt signaling pathway tup04217   Necroptosis tup04550   Signaling pathways regulating pluripotency of stem cells tup04630   JAK-STAT signaling pathway tup04658   Th1 and Th2 cell differentiation tup04659   Th17 cell differentiation tup05161   Hepatitis B tup05162   Measles tup05166   Human T-cell leukemia virus 1 infection tup05169   Epstein-Barr virus infection tup05200   Pathways in cancer tup05203   Viral carcinogenesis tup05223   Non-small cell lung cancer tup05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102471949 (JAK3)    04151 PI3K-Akt signaling pathway     102471949 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     102471949 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     102471949 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     102471949 (JAK3)    04659 Th17 cell differentiation     102471949 (JAK3)    04062 Chemokine signaling pathway     102471949 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102471949 (JAK3)    05203 Viral carcinogenesis     102471949 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     102471949 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102471949 (JAK3)    05161 Hepatitis B     102471949 (JAK3)    05162 Measles     102471949 (JAK3)    05169 Epstein-Barr virus infection     102471949 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     102471949 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:tup01001]     102471949 (JAK3) Enzymes [BR:tup01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102471949 (JAK3) Protein kinases [BR:tup01001]  Non-receptor tyrosine kinases   JAK family [OT]    102471949 (JAK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2_1 FERM_F1 FERM_F2 Jak1_Phl Kinase-like ABC1 Kdo SH2 Haspin_kinase Motif Other DBs NCBI-GeneID:  102471949 NCBI-ProteinID:  XP_006147238 LinkDB All DBs Position Un AA seq 1077 aa AA seqDB search MTPPSEETPLIPQCSSSISSSEAGALHVLLPPRGPGPPQCLTFSFGDLSAEELCVHAAKA SGILPVYSSLFALTTEDLSCWFPPSHIFSVEDAGTQVLLYRLRFRFPNWFGQEKSHRFGL RKDLGSAVVDLPVLEHLFAQHRSDLVSGRLPVGLGLKEQGECLSLAVLDLARMALEQAQR PAELLKTVSYKACLPPGLRALIEGLSFVTRKRIRRTVRQALRRVAAGLADRYSLMHAGAQ DGQGLLRVAGGSGIAWSHGEGEAFQPFGDFPEILDISIKQAPRVGPAGEHRLVTITRTDN HILEAEFPGLLQALSFVALVDGYFRLTTDSQHYFCKEVAPPRLLEEVAERCHGPITLDFA IDKLKTGGSIPGSYVLRRSPKDFDSFLLTVCVQTPLGPDYKGCLIRRDPTQTFSLVGLCR PYNSLRELLAACWDGGLHVDGVALNLTSCCVPRPKEKSNLIVIRRGCGLSSSSPVGPQFH CQLSQMTFQKIPANSLEWHENLGHGSFTKIYRGCLHEAVDGEARKTEVLLKVIDAKHRNC MESFLEAASLMSQVSYQHLVLLHGVCMAGDSTMVQEFVPLGAIDTYLRKRGHLVAASWKL QVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGADGSPPFIKLSDPGVSPSVLSLEMLT DRIPWVAPECLQEARTLGLEADKWGFGATAWEVFSGVTMPVSTLDPAQKLQFYTGRQQLP APKWTELALLIQDCMDYEPGRRPSFRAVIRDLNSLITSDYELLSDSTPGALAPPDGLWSG AQLYAWQDPTIFEERHLKYISQLGKGNFGTVELCRYDPLGDNTGALVAVKQLQHSGPDQQ RDFQREIQILKAMHSDFIVKYRGVSYGPGRQSLRLVMEYLPSGCLRDFLQRHRARLDAGR LLLYASQICKGMEYLGSRRCVHRDLAARNILVENEAHVKIADFGLAKLLPLDKDYYKVRK QGASPVPWYAPESLSDNIFSRQSDVWSFGVVLYELFTYSDKSCSPSAEFLRMMGCELDVP ALCRLLELLTEGQRLPAPPACPGEVHELMKLCWASSPQDRPPFSVLGPQLDALWNKS NT seq 3234 nt NT seq  +upstreamnt  +downstreamnt atgacccctccgagtgaagagacccccctgatcccccagtgctccagtagcatctcgtct tccgaagctggcgccctgcatgtgctgctgcccccccgaggccctgggcccccccagtgc ctcactttctcttttggggacctctcggccgaggagctgtgtgtgcacgccgccaaggcc agtggcatcctgccggtgtattcttccctctttgctctgaccacggaggacctgtcttgc tggtttccacccagccacatcttctccgtggaggacgcaggcacccaagtcctgctctac aggctccgctttcgcttccccaactggttcgggcaggagaagagccaccgcttcgggctt cgcaaggatttgggcagtgccgtggttgaccttccagttctagaacacctctttgcccag caccgaagcgacctggtgagcgggcgcctccccgtgggcctgggccttaaagaacaaggc gaatgtctcagcctggcggtgctggacctggcccggatggcgctggagcaggcccagcgg ccagcagagctactgaagactgtcagctacaaggcctgcctgcccccgggcttacgcgcc ctgatcgagggcctcagcttcgtgacacggaaacgcatccgaaggacggtccgccaggcc ctgcgccgcgtggccgccggcctagccgaccgctattcgctcatgcatgccggtgcccaa gatgggcaggggctgctccgcgtggctggtggcagcgggatcgcctggagccacggagaa ggcgaggccttccagcccttcggggattttccggagatcctggacatcagcattaaacaa gccccgcgcgttggcccggccggggagcaccgtctggtcaccatcacgaggacggataac cacatcctggaggcggagttcccgggcctgctgcaggcgttgtccttcgtggctctcgtg gacggctacttccggctgaccaccgactcccagcactacttctgcaaggaggtggcaccg cctcggctgctggaggaggtggctgaacggtgtcacggtcccatcaccctggattttgcc atcgacaaacttaagactggaggttccattcccggctcctacgtgctccgccgcagcccc aaggacttcgacagcttccttctcactgtctgtgttcagaccccccttggtcctgattac aagggctgcctcatccggagggaccccacacaaaccttctccctggttggcctctgccgg ccctacaacagccttcgagagctcctggcagcgtgctgggatggtggcttacacgtggat ggggtggcgttgaacctcacttcctgctgcgttcccagacccaaagaaaaatccaacctg atcgtgatccggaggggttgtggcctgtcctcgtcatctcccgttgggccccagttccac tgccagctgagccagatgacatttcaaaagatccctgccaacagcctggagtggcatgag aacttgggccatgggtccttcactaagatttaccggggctgcctccatgaggctgtggat ggggaggcccgcaagacagaggtgctgctgaaggtgatagacgccaagcataggaattgc atggagtccttcctggaagccgcgagcttgatgagccaagtgtcctaccagcatctcgtg ttgctccacggcgtgtgcatggccggagacagcaccatggtgcaggaattcgtccccctg ggagccatagacacctacctgcgcaaacgtggccacctggtggccgccagctggaagctg caggtgatcaagcaactggcctatgccctcaactatctggaggacaaaggtctcccccat ggcaatgtctcagcccggaaggtgctcctggcccgggagggggctgatgggagtccgcct ttcattaagctgagtgaccccggtgtcagccccagtgtgctcagcttggagatgctcact gataggattccttgggtggcccccgagtgtctccaggaagcccggacactgggtctggaa gctgacaagtggggcttcggcgccaccgcctgggaggtgttcagcggcgtcacgatgccc gtcagcaccctggatcccgcccagaagctgcagttctatacagggcggcagcagctaccg gcgcccaagtggactgagctggctctgctgatccaggactgcatggactacgagccgggc cggagaccctccttccgagccgtcatccgggacctcaacagcctcatcacgtcagattac gagctcctctcggattccacgcctggcgctctggcgccccctgacgggctgtggagtggt gcccagctctacgcctggcaggaccccacgatcttcgaggagcgacacctcaagtacatc tcccagctgggcaagggcaatttcggcaccgtggagctgtgccgctatgacccgctgggc gacaacaccggcgccctggtggccgtgaagcagctgcagcacagcgggcccgaccagcag cgggacttccagcgcgagatccagatcctcaaagccatgcacagcgacttcatcgtcaag taccgcggcgtcagctacggccctggccgccagagtctccgcctggtcatggagtacctg cccagcggctgcctgcgcgacttcttgcagcgacaccgcgcgcgcctggacgccggccgc ctcctcctctacgcctcgcagatctgcaagggaatggagtacctgggttcccgccgctgc gtgcaccgcgacctggccgcccggaacatcctggtggagaacgaggcgcacgtcaagatc gctgacttcggcctggccaagctgctgccgctggataaagactactacaaagtgagaaag caaggcgccagtccagtgccttggtacgcccccgagtccctctcagacaacatcttctcg cgccagtcggacgtctggagcttcggggtggtcctgtacgagctcttcacctacagcgac aagagctgcagcccctcggccgagttcctccggatgatggggtgtgagctcgatgtcccc gctctctgccgcctcctggagctgctgaccgaaggccagaggttgccagcacctcccgcc tgccctggcgaggttcacgaactcatgaagctctgctgggcttctagcccccaggaccgg ccgccattcagcgtcttgggtccccagctcgacgcgctatggaataaaagttga

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