KEGG   Tupaia chinensis (Chinese tree shrew): 102479515
Entry
102479515         CDS       T02978                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup00670  One carbon pool by folate
tup00790  Folate biosynthesis
tup01100  Metabolic pathways
tup01240  Biosynthesis of cofactors
tup01523  Antifolate resistance
tup04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:tup00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    102479515 (DHFR)
   00670 One carbon pool by folate
    102479515 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    102479515 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    102479515 (DHFR)
Enzymes [BR:tup01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     102479515 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 102479515
NCBI-ProteinID: XP_006143564
UniProt: L9L4C5
LinkDB
Position
Un
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTTSSVEGKQNIVIMGRKTWFS
IPEKNRPLKDRINLVLSRELKEPPQGAHFLAKSLNDALKLIEQPELANQVDMVWIVGGSS
VYKEAMNQPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKF
EVYEKND
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctaaactgcatcgtcgctgtgtcccagaacatgggcatcggcaagaac
ggggacctgccctggcctccgctcaggaatgaatttaagtatttccagagaatgaccaca
acctcttcagtagaaggtaaacaaaatatcgtgattatgggtaggaagacctggttttcc
attcctgaaaagaatcggcctttaaaagacagaattaatttagttctcagtagagaactc
aaggaacctccacaaggagctcattttcttgccaaaagtctgaatgatgccctaaaactt
attgagcaaccagaattagctaatcaagtggacatggtttggatagtgggaggtagttct
gtttataaggaagccatgaaccagccaggccatcttaaactgttcgtgacaaggatcatg
caggattttgaaagtgataccttttttccagaaattgatttggagaaatataaacttctc
ccagaatacccaggtgttctttctgatgtccaggaggagaaaggcattaagtataagttt
gaagtgtatgaaaagaacgactga

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