Tupaia chinensis (Chinese tree shrew): 102483369 Help Entry 102483369         CDS       T02978                                  Symbol PTK2 Name (RefSeq) protein tyrosine kinase 2   KO K05725   focal adhesion kinase 1 [EC:2.7.10.2] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup01522   Endocrine resistance tup04012   ErbB signaling pathway tup04062   Chemokine signaling pathway tup04148   Efferocytosis tup04151   PI3K-Akt signaling pathway tup04360   Axon guidance tup04370   VEGF signaling pathway tup04510   Focal adhesion tup04670   Leukocyte transendothelial migration tup04810   Regulation of actin cytoskeleton tup04935   Growth hormone synthesis, secretion and action tup05100   Bacterial invasion of epithelial cells tup05135   Yersinia infection tup05146   Amoebiasis tup05163   Human cytomegalovirus infection tup05165   Human papillomavirus infection tup05170   Human immunodeficiency virus 1 infection tup05200   Pathways in cancer tup05202   Transcriptional misregulation in cancer tup05205   Proteoglycans in cancer tup05208   Chemical carcinogenesis - reactive oxygen species tup05222   Small cell lung cancer tup05417   Lipid and atherosclerosis tup05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     102483369 (PTK2)    04370 VEGF signaling pathway     102483369 (PTK2)    04151 PI3K-Akt signaling pathway     102483369 (PTK2)  09140 Cellular Processes   09141 Transport and catabolism    04148 Efferocytosis     102483369 (PTK2)   09144 Cellular community - eukaryotes    04510 Focal adhesion     102483369 (PTK2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     102483369 (PTK2)  09150 Organismal Systems   09151 Immune system    04670 Leukocyte transendothelial migration     102483369 (PTK2)    04062 Chemokine signaling pathway     102483369 (PTK2)   09152 Endocrine system    04935 Growth hormone synthesis, secretion and action     102483369 (PTK2)   09158 Development and regeneration    04360 Axon guidance     102483369 (PTK2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102483369 (PTK2)    05202 Transcriptional misregulation in cancer     102483369 (PTK2)    05205 Proteoglycans in cancer     102483369 (PTK2)    05208 Chemical carcinogenesis - reactive oxygen species     102483369 (PTK2)   09162 Cancer: specific types    05222 Small cell lung cancer     102483369 (PTK2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102483369 (PTK2)    05163 Human cytomegalovirus infection     102483369 (PTK2)    05165 Human papillomavirus infection     102483369 (PTK2)   09171 Infectious disease: bacterial    05135 Yersinia infection     102483369 (PTK2)    05100 Bacterial invasion of epithelial cells     102483369 (PTK2)   09174 Infectious disease: parasitic    05146 Amoebiasis     102483369 (PTK2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102483369 (PTK2)    05418 Fluid shear stress and atherosclerosis     102483369 (PTK2)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102483369 (PTK2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:tup01001]     102483369 (PTK2)    01009 Protein phosphatases and associated proteins [BR:tup01009]     102483369 (PTK2) Enzymes [BR:tup01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      102483369 (PTK2) Protein kinases [BR:tup01001]  Non-receptor tyrosine kinases   FAK family    102483369 (PTK2) Protein phosphatases and associated proteins [BR:tup01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      102483369 (PTK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Focal_AT Pkinase FERM_N_2 FERM_C_FAK1 FERM_M Kinase-like Haspin_kinase FERM_F2 ABC1 Motif Other DBs NCBI-GeneID:  102483369 NCBI-ProteinID:  XP_006152174 LinkDB All DBs Position Un AA seq 1112 aa AA seqDB search MLWGRAGPEALKSAGAICMERRGCGPFPRCWAKEYDRYLASSKKMAAAYLDPNLNHTPNS STKVPLSTGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHK VKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFTQVQTIQYSNSEDKDRKGML QLRIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL ANSEKQGVRTHAVSVSDEISGDETDDYAEIIDEEDTYTMPSKSYGIDEARDYEIQRERIE LGRCIGEGQFGDVHQGVYMSPENPALAVAIKTCKNCTSDSVREKFLQEALTMRQFDHPHI VKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLASLILYAYQLSTALAYLESKRFV HRDIAARNVLVSSNDCVKLGDFGLSRYMEDSTYYKASKGKLPIKWMAPESINFRRFTSAS DVWMFGVCMWEILMHGVKPFQGVKNNDVIGRIENGERLPMPPNCPPTLYSLMTKCWAYDP SRRPRFTELKAQLSTILEEEKVQQEERMRMESRRQATVSWDSGGSDEAPPKPSRPGYPSP RSSEGFYPSPQHMVQTNHYQVSGYPGSHGITAMAGSIYPGQASLLDQTEPWNHRPQEIAM WQPNAEDSTPLDLRGLGQVLPTHLMEERLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGS IDREDGSLQGPTGNQHVYQPVGKPDPAAPPKKPPRPGAPGHLGSLASLGSPGDGYNEGVK PWRLQPQEISPPPTANLDRSNDKVYENVTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLA LRTLLATVDETIPVLPASTHREIEMAQKLLNSDLGELINKMKLAQQYVMTSLQQEYKKQM LTAAHALAVDAKNLLDVIDQARLKMLGQTRPH NT seq 3339 nt NT seq  +upstreamnt  +downstreamnt atgttgtggggacgggcaggacccgaggccctgaagtcagcaggggccatctgtatggag agacgcggctgtggtccatttccaaggtgttgggctaaagaatatgacagatacctagca tctagcaaaaaaatggcagctgcttaccttgatccaaacttgaatcacacgccaaattcc agtacgaaggttcccctaagtactggtatggaacgatcccctggtgcaatggagcgagta ttaaaagtctttcattatttcgaaagcaacagtgagccaaccacctgggccagtatcatc aggcatggagatgctactgatgtcaggggcatcattcagaagatagtggacagtcacaag gtaaagcatgtggcctgctatggattccgtctcagtcacctgcggtcagaggaggttcac tggctccacgtggacatgggcgtctccagtgtgagggagaagtatgagcttgcccaccca ccagaggagtggaagtacgaattaagaattcgttatttgccaaaaggatttctaaaccag tttactgaagacaagccaactctgaatttcttctatcaacaggtgaagagtgattacatg ttagagatagctgaccaagtggaccaggaaattgctttgaagttgggttgtctagaaatt cggcgctcctactgggagatgcgtggcaacgcgctggagaagaagtccaactatgaagta ttagaaaaagatgttggtttaaagcgattttttcctaagagtttactggattctgtcaag gccaaaacactaagaaaattgatccagcaaacatttagacagtttgccaaccttaataga gaagaaagcattctgaagttctttgaaatcctgtctccagtgtacagatttgacaaggaa tgcttcaagtgtgctctcggctcaagctggattatttcagtggagctggcgatcggcccc gaagaagggatcagttacctcacagacaagggctgcaaccccacacatctggctgacttc actcaagtgcagaccattcagtattcaaacagcgaagacaaggacaggaaaggaatgcta cagctgagaatagcaggcgctcccgagcctctgacagtgacggcaccatccctaaccatt gcagagaatatggctgacctgatagatggctactgccggctggtgaatggagccacgcag tcttttatcatcaggccccagaaagaaggtgaacgggctttaccatcaataccaaagttg gctaacagtgaaaagcagggtgtgcgaacacacgccgtctctgtgtcagatgaaattagt ggggacgaaacggacgattatgctgagattatcgatgaagaggatacatataccatgccc tcaaaaagctatggaatagatgaagccagggattatgagattcaaagagaaagaatagaa cttggacgatgtatcggagaaggccaatttggagatgtacatcaaggcgtttacatgagt ccagagaatccagctctggcggttgcaattaaaacatgtaaaaactgtacttcggacagc gtgagagagaaatttcttcaagaagccttaacgatgcgtcagtttgaccatcctcacatt gtgaagctcatcggcgtcattacagagaacccggtctggatcatcatggagctgtgtacc ctcggagagctgaggtcatttttgcaagtaaggaaatacagtttggatctagcatctttg atcctgtatgcctaccagctcagtacagctcttgcgtatctagagagtaagagatttgtt cacagagatattgctgctcgaaatgttctggtgtcctcgaatgactgtgtgaaattagga gactttggattatcccgatacatggaagatagtacttattacaaagcttccaaaggaaaa ttgcctattaaatggatggcgccagagtccatcaatttccgacgttttacctcagctagt gacgtgtggatgtttggtgtgtgcatgtgggagatcctgatgcacggcgtgaagcctttc caaggagtgaagaacaacgacgtgattgggcgcatcgaaaacggggagaggttaccgatg cctccaaactgccctcctaccctctacagccttatgacgaagtgctgggcctacgatccc agccggcggccgcggtttactgagctcaaagctcagctcagcacaatcctagaggaggag aaggtgcagcaagaagaacggatgaggatggagtcccgaagacaggctacggtgtcctgg gactccggagggtccgatgaagcaccgcccaagcccagcaggcctggttatcctagtcca aggtccagcgaaggattttaccccagcccacagcacatggtacagaccaatcactaccag gtctctggctaccctggttcacacggaatcacggccatggctggcagcatctacccaggt caggcatctcttctggaccaaacagaaccatggaaccatagacctcaggagatagccatg tggcagcccaatgcggaggactcgactccgctggatctgcgaggactcgggcaggtgctg ccaacccacctgatggaggagcgactgatccgacagcagcaggagatggaagaggatcag cgctggctggagaaggaggagagattcctgaaacccgacgtgaggctctctcgaggtagc atcgacagggaagacgggagtcttcagggtccgactgggaaccaacacgtgtatcagcct gtggggaagccggatcctgcggctccaccaaagaagcccccacgccccggagcccctggt cacctgggcagccttgccagcctcggcagccctggggacggctataacgagggcgtcaag ccgtggaggctgcagccccaggaaatcagccccccacccaccgccaacctggaccggtcc aatgacaaggtgtatgagaacgtgacgggcctggtgaaagctgtcatcgagatgtccagt aagatccagccggccccgccagaggagtatgtccctatggtgaaggaagtcggcttggcc ctgaggactttgctggccactgtggatgagaccatccctgtcctgccagccagcacgcat cgagagattgagatggcgcagaagttgctgaactctgacctgggagagctcatcaacaag atgaagctggcccagcagtatgtcatgaccagcctgcagcaggagtacaagaagcaaatg ctgaccgcggcccacgccctggccgtggacgccaagaacttactcgacgtcattgaccaa gccagactgaaaatgctggggcagaccagaccgcactga

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