Tupaia chinensis (Chinese tree shrew): 102484500
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Entry
102484500 CDS
T02978
Symbol
PIK3R1
Name
(RefSeq) phosphoinositide-3-kinase regulatory subunit 1
KO
K02649
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup01521
EGFR tyrosine kinase inhibitor resistance
tup01522
Endocrine resistance
tup01524
Platinum drug resistance
tup04012
ErbB signaling pathway
tup04014
Ras signaling pathway
tup04015
Rap1 signaling pathway
tup04024
cAMP signaling pathway
tup04062
Chemokine signaling pathway
tup04066
HIF-1 signaling pathway
tup04068
FoxO signaling pathway
tup04070
Phosphatidylinositol signaling system
tup04071
Sphingolipid signaling pathway
tup04072
Phospholipase D signaling pathway
tup04081
Hormone signaling
tup04140
Autophagy - animal
tup04150
mTOR signaling pathway
tup04151
PI3K-Akt signaling pathway
tup04152
AMPK signaling pathway
tup04210
Apoptosis
tup04211
Longevity regulating pathway
tup04213
Longevity regulating pathway - multiple species
tup04218
Cellular senescence
tup04360
Axon guidance
tup04370
VEGF signaling pathway
tup04380
Osteoclast differentiation
tup04510
Focal adhesion
tup04550
Signaling pathways regulating pluripotency of stem cells
tup04611
Platelet activation
tup04613
Neutrophil extracellular trap formation
tup04620
Toll-like receptor signaling pathway
tup04625
C-type lectin receptor signaling pathway
tup04630
JAK-STAT signaling pathway
tup04650
Natural killer cell mediated cytotoxicity
tup04660
T cell receptor signaling pathway
tup04662
B cell receptor signaling pathway
tup04664
Fc epsilon RI signaling pathway
tup04666
Fc gamma R-mediated phagocytosis
tup04668
TNF signaling pathway
tup04670
Leukocyte transendothelial migration
tup04722
Neurotrophin signaling pathway
tup04725
Cholinergic synapse
tup04750
Inflammatory mediator regulation of TRP channels
tup04810
Regulation of actin cytoskeleton
tup04910
Insulin signaling pathway
tup04914
Progesterone-mediated oocyte maturation
tup04915
Estrogen signaling pathway
tup04917
Prolactin signaling pathway
tup04919
Thyroid hormone signaling pathway
tup04923
Regulation of lipolysis in adipocytes
tup04926
Relaxin signaling pathway
tup04929
GnRH secretion
tup04930
Type II diabetes mellitus
tup04931
Insulin resistance
tup04932
Non-alcoholic fatty liver disease
tup04933
AGE-RAGE signaling pathway in diabetic complications
tup04935
Growth hormone synthesis, secretion and action
tup04960
Aldosterone-regulated sodium reabsorption
tup04973
Carbohydrate digestion and absorption
tup05010
Alzheimer disease
tup05017
Spinocerebellar ataxia
tup05020
Prion disease
tup05100
Bacterial invasion of epithelial cells
tup05135
Yersinia infection
tup05142
Chagas disease
tup05146
Amoebiasis
tup05160
Hepatitis C
tup05161
Hepatitis B
tup05162
Measles
tup05163
Human cytomegalovirus infection
tup05164
Influenza A
tup05165
Human papillomavirus infection
tup05166
Human T-cell leukemia virus 1 infection
tup05167
Kaposi sarcoma-associated herpesvirus infection
tup05168
Herpes simplex virus 1 infection
tup05169
Epstein-Barr virus infection
tup05170
Human immunodeficiency virus 1 infection
tup05171
Coronavirus disease - COVID-19
tup05200
Pathways in cancer
tup05203
Viral carcinogenesis
tup05205
Proteoglycans in cancer
tup05206
MicroRNAs in cancer
tup05207
Chemical carcinogenesis - receptor activation
tup05208
Chemical carcinogenesis - reactive oxygen species
tup05210
Colorectal cancer
tup05211
Renal cell carcinoma
tup05212
Pancreatic cancer
tup05213
Endometrial cancer
tup05214
Glioma
tup05215
Prostate cancer
tup05218
Melanoma
tup05220
Chronic myeloid leukemia
tup05221
Acute myeloid leukemia
tup05222
Small cell lung cancer
tup05223
Non-small cell lung cancer
tup05224
Breast cancer
tup05225
Hepatocellular carcinoma
tup05226
Gastric cancer
tup05230
Central carbon metabolism in cancer
tup05231
Choline metabolism in cancer
tup05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
tup05415
Diabetic cardiomyopathy
tup05417
Lipid and atherosclerosis
tup05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
102484500 (PIK3R1)
04014 Ras signaling pathway
102484500 (PIK3R1)
04015 Rap1 signaling pathway
102484500 (PIK3R1)
04370 VEGF signaling pathway
102484500 (PIK3R1)
04630 JAK-STAT signaling pathway
102484500 (PIK3R1)
04668 TNF signaling pathway
102484500 (PIK3R1)
04066 HIF-1 signaling pathway
102484500 (PIK3R1)
04068 FoxO signaling pathway
102484500 (PIK3R1)
04070 Phosphatidylinositol signaling system
102484500 (PIK3R1)
04072 Phospholipase D signaling pathway
102484500 (PIK3R1)
04071 Sphingolipid signaling pathway
102484500 (PIK3R1)
04024 cAMP signaling pathway
102484500 (PIK3R1)
04151 PI3K-Akt signaling pathway
102484500 (PIK3R1)
04152 AMPK signaling pathway
102484500 (PIK3R1)
04150 mTOR signaling pathway
102484500 (PIK3R1)
09133 Signaling molecules and interaction
04081 Hormone signaling
102484500 (PIK3R1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
102484500 (PIK3R1)
09143 Cell growth and death
04210 Apoptosis
102484500 (PIK3R1)
04218 Cellular senescence
102484500 (PIK3R1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102484500 (PIK3R1)
04550 Signaling pathways regulating pluripotency of stem cells
102484500 (PIK3R1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102484500 (PIK3R1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102484500 (PIK3R1)
04613 Neutrophil extracellular trap formation
102484500 (PIK3R1)
04620 Toll-like receptor signaling pathway
102484500 (PIK3R1)
04625 C-type lectin receptor signaling pathway
102484500 (PIK3R1)
04650 Natural killer cell mediated cytotoxicity
102484500 (PIK3R1)
04660 T cell receptor signaling pathway
102484500 (PIK3R1)
04662 B cell receptor signaling pathway
102484500 (PIK3R1)
04664 Fc epsilon RI signaling pathway
102484500 (PIK3R1)
04666 Fc gamma R-mediated phagocytosis
102484500 (PIK3R1)
04670 Leukocyte transendothelial migration
102484500 (PIK3R1)
04062 Chemokine signaling pathway
102484500 (PIK3R1)
09152 Endocrine system
04910 Insulin signaling pathway
102484500 (PIK3R1)
04923 Regulation of lipolysis in adipocytes
102484500 (PIK3R1)
04929 GnRH secretion
102484500 (PIK3R1)
04915 Estrogen signaling pathway
102484500 (PIK3R1)
04914 Progesterone-mediated oocyte maturation
102484500 (PIK3R1)
04917 Prolactin signaling pathway
102484500 (PIK3R1)
04926 Relaxin signaling pathway
102484500 (PIK3R1)
04935 Growth hormone synthesis, secretion and action
102484500 (PIK3R1)
04919 Thyroid hormone signaling pathway
102484500 (PIK3R1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
102484500 (PIK3R1)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
102484500 (PIK3R1)
09156 Nervous system
04725 Cholinergic synapse
102484500 (PIK3R1)
04722 Neurotrophin signaling pathway
102484500 (PIK3R1)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
102484500 (PIK3R1)
09158 Development and regeneration
04360 Axon guidance
102484500 (PIK3R1)
04380 Osteoclast differentiation
102484500 (PIK3R1)
09149 Aging
04211 Longevity regulating pathway
102484500 (PIK3R1)
04213 Longevity regulating pathway - multiple species
102484500 (PIK3R1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102484500 (PIK3R1)
05206 MicroRNAs in cancer
102484500 (PIK3R1)
05205 Proteoglycans in cancer
102484500 (PIK3R1)
05207 Chemical carcinogenesis - receptor activation
102484500 (PIK3R1)
05208 Chemical carcinogenesis - reactive oxygen species
102484500 (PIK3R1)
05203 Viral carcinogenesis
102484500 (PIK3R1)
05230 Central carbon metabolism in cancer
102484500 (PIK3R1)
05231 Choline metabolism in cancer
102484500 (PIK3R1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102484500 (PIK3R1)
09162 Cancer: specific types
05210 Colorectal cancer
102484500 (PIK3R1)
05212 Pancreatic cancer
102484500 (PIK3R1)
05225 Hepatocellular carcinoma
102484500 (PIK3R1)
05226 Gastric cancer
102484500 (PIK3R1)
05214 Glioma
102484500 (PIK3R1)
05221 Acute myeloid leukemia
102484500 (PIK3R1)
05220 Chronic myeloid leukemia
102484500 (PIK3R1)
05218 Melanoma
102484500 (PIK3R1)
05211 Renal cell carcinoma
102484500 (PIK3R1)
05215 Prostate cancer
102484500 (PIK3R1)
05213 Endometrial cancer
102484500 (PIK3R1)
05224 Breast cancer
102484500 (PIK3R1)
05222 Small cell lung cancer
102484500 (PIK3R1)
05223 Non-small cell lung cancer
102484500 (PIK3R1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
102484500 (PIK3R1)
05170 Human immunodeficiency virus 1 infection
102484500 (PIK3R1)
05161 Hepatitis B
102484500 (PIK3R1)
05160 Hepatitis C
102484500 (PIK3R1)
05171 Coronavirus disease - COVID-19
102484500 (PIK3R1)
05164 Influenza A
102484500 (PIK3R1)
05162 Measles
102484500 (PIK3R1)
05168 Herpes simplex virus 1 infection
102484500 (PIK3R1)
05163 Human cytomegalovirus infection
102484500 (PIK3R1)
05167 Kaposi sarcoma-associated herpesvirus infection
102484500 (PIK3R1)
05169 Epstein-Barr virus infection
102484500 (PIK3R1)
05165 Human papillomavirus infection
102484500 (PIK3R1)
09171 Infectious disease: bacterial
05135 Yersinia infection
102484500 (PIK3R1)
05100 Bacterial invasion of epithelial cells
102484500 (PIK3R1)
09174 Infectious disease: parasitic
05146 Amoebiasis
102484500 (PIK3R1)
05142 Chagas disease
102484500 (PIK3R1)
09164 Neurodegenerative disease
05010 Alzheimer disease
102484500 (PIK3R1)
05017 Spinocerebellar ataxia
102484500 (PIK3R1)
05020 Prion disease
102484500 (PIK3R1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102484500 (PIK3R1)
05418 Fluid shear stress and atherosclerosis
102484500 (PIK3R1)
05415 Diabetic cardiomyopathy
102484500 (PIK3R1)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
102484500 (PIK3R1)
04932 Non-alcoholic fatty liver disease
102484500 (PIK3R1)
04931 Insulin resistance
102484500 (PIK3R1)
04933 AGE-RAGE signaling pathway in diabetic complications
102484500 (PIK3R1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102484500 (PIK3R1)
01524 Platinum drug resistance
102484500 (PIK3R1)
01522 Endocrine resistance
102484500 (PIK3R1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
tup04131
]
102484500 (PIK3R1)
Membrane trafficking [BR:
tup04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
102484500 (PIK3R1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI3K_P85_iSH2
SH2
RhoGAP
SH2_1
SH3_1
SH3_2
AAA_13
SH3_9
Laminin_I
FWWh
Exonuc_VII_L
Motif
Other DBs
NCBI-GeneID:
102484500
NCBI-ProteinID:
XP_006169589
LinkDB
All DBs
Position
Un
AA seq
725 aa
AA seq
DB search
MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVAHGFSDGQEARPEEIGWLNGYN
ETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTETDSEQQALTLPDLAE
QFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSTPAELRQLLDCDTASVDLEMIDVH
VLADAFKRYLLDLPNPVIPVAVYSEMISLAQEVQSSEEYTQLLKKLIRSPHIPHQYWLTL
QYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFPATSSDSTEHFTKVVEILIATEWSE
RQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA
STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFNSVVELINHYRNESLAQYNPKL
DVKLLYPVSKYQQDQVVKEDNIEAVGFKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQM
KRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEII
DSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG
NENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYAC
SVVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVY
AQQRR
NT seq
2178 nt
NT seq
+upstream
nt +downstream
nt
atgagtgccgagggctaccagtaccgagcgctgtacgactataagaaggaacgagaggaa
gatatcgacttgcacttgggtgacattttgactgtgaataaaggatctttagtagcacat
ggattcagtgatggacaagaagccagacctgaagaaatcggctggttaaatggctataat
gaaaccacgggggagaggggagactttccgggaacttatgtagaatatattggaaggaaa
aaaatctcacccccgacaccaaagccccggccacctcgaccccttcctgttgcaccaggt
tcttctaaaactgaaacagacagtgaacaacaagctttgactcttccagatcttgcagag
cagttcgcccctcctgacattgccccacctcttctgatcaagcttgtggaagccattgaa
aagaaaggtctggaatgttcaactctatacagaacacagagctccagcaccccagcagaa
ttacgacagcttcttgattgtgatacggcttctgtggacttggaaatgatcgatgtgcac
gttttagcagatgctttcaaacgctatctcctggacttaccaaatcctgtcattccagta
gccgtttacagtgaaatgatttctttagcccaagaagtacaaagctccgaagaatatacc
cagctattgaagaagctcattagatcgcctcacatacctcatcagtattggcttacactt
cagtatctgctgaaacatttcttcaagctctctcaaacctccagcaaaaatctcttgaat
gcaagagtgctctcagaaattttcagccctatgcttttcagattcccagcaaccagctct
gatagtaccgaacacttcacaaaagttgtagaaattttaattgcaactgaatggagtgag
cgacagcctgcaccagcactgccacctaagccaccaaaacccactactgtagccaacaac
ggtatgaataacaatatgtccttacaagatgctgaatggtactggggtgatatctcaagg
gaagaagtaaatgaaaaacttcgagatacagcagatgggacctttctggtacgagatgca
tctactaaaatgcatggtgattatactcttacactaaggaaaggaggaaataacaaatta
atcaaaatatttcaccgagatgggaaatatggcttctctgacccattaaccttcaattct
gtggttgaattaataaaccactaccggaatgaatctctagctcagtataatcccaaactg
gatgtgaaattactttatccagtatccaaataccaacaggatcaggttgtcaaagaagat
aatattgaagctgtaggttttaaaaagttacatgaatataacactcagtttcaagaaaag
agtagagaatatgatagattgtatgaagaatatactcgtacttcccaggaaattcaaatg
aaaagaacagctattgaagcatttaatgaaaccataaaaatatttgaagaacagtgccaa
acccaggagaggtacagcaaagagtatatagagaagtttaaacgtgaaggcaatgaaaaa
gaaatacaaaggattatgcataattatgataagttaaagtctcgaatcagtgagattatt
gacagtagaagaagattggaggaagacctcaagaagcaggcagctgagtaccgagagatc
gacaaacgcatgaacagcattaaaccagacctcattcagctgagaaagacgagagaccaa
tacttgatgtggttgacccaaaaaggtgttcggcagaagaagttgaacgaatggttgggc
aatgaaaacactgaggaccaatattccctggtggaagacgatgaggatttgccccaccac
gatgagaagacgtggaatgtcggaagcagcaaccgaaataaagctgaaaacctgttgcgg
gggaagcgagatggcacatttctagtccgggagagcagtaaacagggctgctatgcctgc
tctgtagtggtggacggtgaagtaaagcactgtgtcatcaacaagacggcgaccggctat
ggctttgctgagccctataacttgtacagctctctgaaagaactggtgctacattaccaa
cacacctccctcgtgcagcacaatgactccctcaacgtcacactagcctacccggtatat
gcacagcagaggcgatga
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integrated database retrieval system
