Tupaia chinensis (Chinese tree shrew): 102485136
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Entry
102485136 CDS
T02978
Symbol
PTPN11
Name
(RefSeq) protein tyrosine phosphatase, non-receptor type 11
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup04014
Ras signaling pathway
tup04072
Phospholipase D signaling pathway
tup04148
Efferocytosis
tup04360
Axon guidance
tup04625
C-type lectin receptor signaling pathway
tup04630
JAK-STAT signaling pathway
tup04650
Natural killer cell mediated cytotoxicity
tup04660
T cell receptor signaling pathway
tup04670
Leukocyte transendothelial migration
tup04722
Neurotrophin signaling pathway
tup04920
Adipocytokine signaling pathway
tup04931
Insulin resistance
tup05168
Herpes simplex virus 1 infection
tup05205
Proteoglycans in cancer
tup05208
Chemical carcinogenesis - reactive oxygen species
tup05211
Renal cell carcinoma
tup05220
Chronic myeloid leukemia
tup05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
102485136 (PTPN11)
04630 JAK-STAT signaling pathway
102485136 (PTPN11)
04072 Phospholipase D signaling pathway
102485136 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
102485136 (PTPN11)
09150 Organismal Systems
09151 Immune system
04625 C-type lectin receptor signaling pathway
102485136 (PTPN11)
04650 Natural killer cell mediated cytotoxicity
102485136 (PTPN11)
04660 T cell receptor signaling pathway
102485136 (PTPN11)
04670 Leukocyte transendothelial migration
102485136 (PTPN11)
09152 Endocrine system
04920 Adipocytokine signaling pathway
102485136 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
102485136 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
102485136 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
102485136 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
102485136 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102485136 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
102485136 (PTPN11)
05211 Renal cell carcinoma
102485136 (PTPN11)
09172 Infectious disease: viral
05168 Herpes simplex virus 1 infection
102485136 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
102485136 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
tup01009
]
102485136 (PTPN11)
Enzymes [BR:
tup01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
102485136 (PTPN11)
Protein phosphatases and associated proteins [BR:
tup01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
102485136 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
PTPlike_phytase
Y_phosphatase3
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
102485136
NCBI-ProteinID:
XP_006148032
LinkDB
All DBs
Position
Un
AA seq
593 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDEYSLKEYGVMRVRNVKESAAHDYTLRELKLSKVGQGNTERTVWQYHF
RTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIR
EKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGH
EYTNIKYSLTDQTSGDQSPLPPCTPTPPCAEMREDNARVYENVGLMQQQKSFR
NT seq
1782 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaatatcaccggcgtagaggcagaaaacctactg
ctgacgagaggagttgatggcagttttttggcaagacccagtaaaagcaaccctggagac
ttcacgctttctgttagaaggaatggagctgtcacccacatcaagattcagaacactggt
gattactatgacctgtacggaggggagaagtttgccactctggctgaactggtccagtat
tacatggagcaccacgggcagttaaaggagaagaatggagatgttattgagctcaaatat
cctctgaactgtgcagatcctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattactaaccgagaaaggaaaacatggtagctttcttgtgcgagagagc
cagagccaccctggagatttcgttctgtctgtccgcaccggtgatgacaaaggggagagc
aatgacggcaaatctaaagtgactcatgtcatgattcgctgtcaggaactgaaatacgat
gtcggtggaggagaacggtttgattctttgacagatcttgtggaacattacaagaagaat
cctatggtggaaacgctgggcacagtactacagctcaagcagcccctcaacacaactcgt
attaatgctgctgaaatagaaagtcgagttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggtttttgggaagaattcgagacactacaacaacaggagtgtaaa
cttctctatagccgaaaagagggtcagaggcaagaaaataaaaataaaaatagatataaa
aacattctgccctttgatcataccagggtcgtcctgcatgatggtgatcccaacgagcct
gtttccgattacatcaatgcgaatattatcatgcctgaatttgaaaccaagtgcaacaat
tcaaagcctaagaagagttatatcgccacacaaggctgcctgcaaaacacggtaaacgac
ttttggcggatggtgttccaggagaactcgcgagtgattgtcatgacaacaaaagaagta
gagagagggaagagtaaatgtgtcaagtactggcccgatgagtactcactgaaagaatat
ggggtcatgcgtgttaggaatgtcaaagaaagtgctgcgcatgactacacgttaagggaa
cttaaactctccaaggtcggacaagggaatacggagagaacggtctggcagtaccacttt
cggacctggccggaccacggagtgcccagtgaccctggaggtgtgctggacttcttagag
gaggtgcaccataaacaggagagcatcatggacgcagggccagttgtggtgcactgcagt
gctggaattggccggacaggaacattcatcgtgattgacatcctgattgacattatcaga
gagaaaggtgtcgactgtgacatcgacgttcccaaaaccatccagatggtgcggtcccag
aggtcagggatggtccagacagaagcacagtaccgatttatctacatggccgtccagcat
tatattgaaacactacagcgcaggattgaggaagagcagaagagcaagaggaaagggcac
gaatataccaatattaagtattccctaacggaccagacaagcggagatcagagccccctc
ccgccttgcaccccaacgccaccctgtgcggaaatgagagaagataatgctagagtctat
gaaaacgtgggcctgatgcaacagcagaaaagtttcagatga
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