Tupaia chinensis (Chinese tree shrew): 102490242
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Entry
102490242 CDS
T02978
Symbol
ROCK2
Name
(RefSeq) Rho associated coiled-coil containing protein kinase 2
KO
K17388
Rho-associated protein kinase 2 [EC:
2.7.11.39
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup04022
cGMP-PKG signaling pathway
tup04024
cAMP signaling pathway
tup04062
Chemokine signaling pathway
tup04071
Sphingolipid signaling pathway
tup04270
Vascular smooth muscle contraction
tup04310
Wnt signaling pathway
tup04360
Axon guidance
tup04510
Focal adhesion
tup04520
Adherens junction
tup04530
Tight junction
tup04611
Platelet activation
tup04670
Leukocyte transendothelial migration
tup04810
Regulation of actin cytoskeleton
tup04921
Oxytocin signaling pathway
tup05132
Salmonella infection
tup05135
Yersinia infection
tup05163
Human cytomegalovirus infection
tup05200
Pathways in cancer
tup05205
Proteoglycans in cancer
tup05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
102490242 (ROCK2)
04071 Sphingolipid signaling pathway
102490242 (ROCK2)
04024 cAMP signaling pathway
102490242 (ROCK2)
04022 cGMP-PKG signaling pathway
102490242 (ROCK2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102490242 (ROCK2)
04520 Adherens junction
102490242 (ROCK2)
04530 Tight junction
102490242 (ROCK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102490242 (ROCK2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102490242 (ROCK2)
04670 Leukocyte transendothelial migration
102490242 (ROCK2)
04062 Chemokine signaling pathway
102490242 (ROCK2)
09152 Endocrine system
04921 Oxytocin signaling pathway
102490242 (ROCK2)
09153 Circulatory system
04270 Vascular smooth muscle contraction
102490242 (ROCK2)
09158 Development and regeneration
04360 Axon guidance
102490242 (ROCK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102490242 (ROCK2)
05205 Proteoglycans in cancer
102490242 (ROCK2)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
102490242 (ROCK2)
09171 Infectious disease: bacterial
05132 Salmonella infection
102490242 (ROCK2)
05135 Yersinia infection
102490242 (ROCK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102490242 (ROCK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tup01001
]
102490242 (ROCK2)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
tup03036
]
102490242 (ROCK2)
Enzymes [BR:
tup01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
102490242 (ROCK2)
Protein kinases [BR:
tup01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
102490242 (ROCK2)
Chromosome and associated proteins [BR:
tup03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
102490242 (ROCK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH_MRCK
PH
C1_1
Cortex-I_coil
APH
Pkinase_C
Motif
Other DBs
NCBI-GeneID:
102490242
NCBI-ProteinID:
XP_014444991
LinkDB
All DBs
Position
Un
AA seq
1391 aa
AA seq
DB search
MADELAFNFAANRFKTDGLNSLVLDLDFPALRKNKNIDNFLNRYEKIVKKIRGLQMKAED
YDVVKVIGKRGAFGEVQLVRHKASQKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSP
WVVQLFCAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWAKFYTAEVVLALDAIHSMGL
IHRDVKPDNMLLDKHGHLKLADFGTCMKMDEAGMVHCDTAVGTPDYISPEVLKSQGGDGY
YGRECDWWSVGVFLFEMLVGDTPFYADSLVGTYSKIMDHKNSLCFPEDAEISKHAKNLIC
AFLTDREVRLGRNGVEEIKQHPFFKNDQWNWDNIRETAAPVVPELSSDIDSSNFDDIEDD
KGDVETFPIPKAFVGNQLPFIGFTYYRENLLLSDSPSCRENDSIQSRKNEESQEDIKWAA
RISDSPVRTSVLTLDQRCSSPEQLHVMIQKKLYTLEEHLSNEIQAKEELEQKCKSVNARL
EKTIKELEEEITLRKNVESSLRQLEREKALLQHKNAEFQRKADHEADKKRNLENDVNSLK
DQLEDLKKRNQNSQISTEKVNQLQRQLDETNALLRTESDTAARLRKTQAESSKQIQQLES
NNRDLQDKNCLLETAKLKLEKEYINLQSALESERRDRTHGSEIINDLQGRISGLEEDLKN
GKILLAKVELEKRQLQERFADLEKEKSNMEIDMTYQLKVTQQSLEQEEAEHKATKARLAD
KNKIYESIEEAKSEAMKEMEKKLLEERTLKQKVENLLLEAEKKCSILDCDLKQSQQKMNE
LLKQKDVLNEDVRNLTLKIEQETQKRCLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEM
KLSLEKQNAELRKERQDADGQMKELQDQLEAEQYFSTLYKTQVRELKEECEEKTKLCKEL
QQKKQELQDERDSLAAQLEITLTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARH
KQELTEKDATIASLEETNRTLTSDVANLANEKEELNNKLKDAQEQLSRLKDEEISIAAVK
AQFEKQLLNERTLKTQAVNKLAEIMNRKEPVKRGSDTDMRRKEKENRKLHMELKSEREKL
TQQMIKYQKELNEMQAQIAEESQIRIELQMTLDSKDSDIEQLRSQLQALHIGLDSSSIGS
GPGDAEADDSFPESRLEGWLSLPVRNNTKKFGWVKKYVIVSSKKILFYDSEQDKEQSNPY
MVLDIDKLFHVRPVTQTDVYRADAKEIPRIFQILYANEGESKKEQEFPVEPVGEKSNYIC
HKGHEFIPTLYHFPTNCEACMKPLWHMFKPPPALECRRCHIKCHKDHMDKKEEIIAPCKV
YYDISTAKNLLLLANSTEEQQKWVSRLVKKIPKKPPAPDPFARSSPRTSMKIQQNQSIRR
PSRQLAPNKPS
NT seq
4176 nt
NT seq
+upstream
nt +downstream
nt
atggctgatgaacttgccttcaactttgctgcaaacagatttaaaactgatggcttaaat
tccttggtccttgatttggattttcctgctttgaggaaaaacaagaatatagataacttt
ttaaatagatatgagaaaattgtgaaaaaaatcagaggtctgcagatgaaggcagaagac
tatgatgttgtaaaggttatcggaaaaagaggtgcttttggtgaagtccagttggttcgt
cataaggcatcacagaaggtttatgccatgaagcttcttagtaagtttgaaatgataaaa
agatcagattctgcttttttctgggaagaaagagatattatggcctttgccaatagtccc
tgggtggttcagctcttttgtgcctttcaagatgataggtatctgtacatggtaatggag
tacatgcctggtggtgaccttgtaaaccttatgagtaattacgatgtgcctgaaaagtgg
gccaaattttacactgctgaagttgtccttgctctggacgcaatacactccatgggtctc
attcacagggacgtgaagcccgacaacatgctcttggataaacacggacatctaaaatta
gcagattttggcacatgtatgaagatggatgaagcaggcatggtacactgtgacacagca
gttgggacacctgattatatatcacctgaggttctgaaatctcaagggggtgatggttac
tatgggcgagaatgtgattggtggtctgtaggtgttttcctttttgagatgctagtgggg
gatactccattttatgcagattcacttgtaggaacatatagcaaaatcatggatcataag
aattcattatgttttcctgaagatgcagaaatttcaaagcatgcgaagaatctcatctgt
gccttcttaaccgatagggaggtacgactcgggagaaatggagtcgaagaaattaaacag
caccctttctttaagaacgatcagtggaattgggataacataagagagacggcagctcct
gtggtccctgagctcagcagtgacatagacagcagcaattttgatgacatcgaagatgat
aaaggagatgtagaaactttcccaattcctaaagcttttgtgggaaatcagctgcctttt
ataggattcacctactacagagaaaatttgttattaagtgactctccatcttgtagagaa
aatgattcaatacaatcaagaaaaaatgaagaaagccaagaggatataaaatgggcagca
agaatttctgattcccctgtgcgaactagtgtgctcacattagaccaacgctgcagcagc
ccagagcagttacacgtgatgattcagaaaaaactgtatacattagaagaacaccttagc
aatgagatccaagccaaagaggagctagagcagaagtgcaaatctgttaacgctcgccta
gagaagacgatcaaggagctagaggaagagattactttgaggaaaaatgtggaatcatca
ttaagacaattagaaagagaaaaggctcttcttcagcacaaaaatgcagaattccagcgg
aaagctgatcatgaagcagacaagaaacgaaatttggaaaatgatgttaacagcttaaaa
gatcaacttgaagatttgaaaaaaagaaatcaaaactcccaaatatccaccgaaaaagtg
aatcaactccagagacaactggatgaaaccaatgctttgctgcggacagaatccgatacc
gcagcccgtttaagaaaaacccaggcagaaagttccaaacagattcagcagctggaatct
aacaatagagacctgcaagataaaaactgcctgcttgagactgccaagttaaaacttgaa
aaggagtatatcaatcttcagtctgctctggaatctgaacggagggaccggacgcatggg
tcagaaataattaatgatctacaaggtagaatatctggcctggaagaagatttaaagaat
ggcaaaatcttactagcaaaagtagaactggaaaagaggcaattgcaggagagatttgct
gatttggaaaaggaaaagagcaacatggaaatagatatgacataccaactaaaagttaca
cagcagagcttggaacaagaagaggctgagcacaaggccacaaaagcacggctggcagat
aagaataagatctacgagtccattgaagaagcgaaatcagaagctatgaaagaaatggaa
aagaagctcttggaggaaaggactttaaaacagaaagtggaaaacctgttgctggaggct
gagaagaagtgctctatattagactgcgacctcaaacagtcacagcagaagatgaacgag
ctccttaaacagaaggatgtgctaaacgaggatgttagaaacttgacattaaaaatagag
caggaaactcagaagcgctgtttgacacaaaatgacttgaagatgcaaacccagcaggtt
aacactctaaagatgtcagaaaagcagttaaaacaagagaataatcatctcatggaaatg
aaactgagcttggaaaaacaaaatgctgaacttcgaaaagaacggcaagacgcagacggg
cagatgaaagaacttcaggaccagctcgaagctgagcagtatttctcaaccctctataaa
acacaagttagggaacttaaggaagagtgtgaagaaaagaccaaactttgtaaagaactg
cagcaaaagaaacaggaattacaggatgaaagggactccttggctgcccagctggagatc
accttgaccaaagccgattcagagcagctggcccgttccatcgccgaggaacaatattcc
gatctggaaaaagagaagatcatgaaagagctggagatcaaagagatgatggctagacac
aagcaggagcttacggaaaaggacgccaccattgcatcccttgaagaaactaataggaca
ctaactagtgatgttgccaatcttgctaatgagaaagaagaattaaacaacaaactgaaa
gacgctcaagaacaactatcaaggttgaaagatgaagagataagcatagcagctgttaaa
gcacaattcgagaaacagctgctaaacgagagaacactcaaaactcaagctgtgaacaag
ttggctgagatcatgaatcgtaaagaacctgtcaagcgcggcagcgacacggatatgcgg
agaaaagagaaggagaataggaagctacacatggagctgaagtctgagcgggaaaagctg
acccagcagatgatcaagtatcagaaagagctgaatgaaatgcaggcgcaaatagctgaa
gagagccagattcgaattgagctgcagatgacgctggacagcaaggacagtgacatcgag
cagctgcggtcgcagctgcaggccctgcacatcggtctggacagttccagtatcggcagc
gggccgggggacgccgaggcagatgacagctttccagaatcaagactagaaggatggctt
tcactgcctgtgcgaaacaacactaagaaatttggatgggttaaaaagtatgtgattgtg
agcagtaagaagattcttttctatgacagcgaacaagacaaagagcagtctaatccttac
atggtcctggatatagacaagttatttcacgtgcggcccgtcacacagacagatgtgtat
agagcagatgctaaagaaatcccaaggatattccagattctatatgccaatgaaggagaa
agtaagaaggagcaagaatttccagtggagcccgtgggagaaaagtctaattatatttgc
cacaaagggcatgagtttattcctactctttatcatttcccgaccaactgcgaggcttgt
atgaaacctctgtggcacatgtttaagccacccccggctttagagtgtcgtcgctgccat
attaaatgtcataaagaccacatggacaaaaaggaagagatcatagcgccttgcaaagtg
tattatgatatttcaacggcaaagaatctattattgttagcaaattctacagaagagcag
caaaagtgggtgagtcggttggtgaaaaagatacctaaaaagccccctgctccagaccct
ttcgcaaggtcatctcctagaacctcgatgaagatacaacaaaaccagtctatcagacgg
ccgagtcggcagctcgccccaaacaagccaagctaa
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integrated database retrieval system
