Tupaia chinensis (Chinese tree shrew): 102490639 Help Entry 102490639         CDS       T02978                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup00230   Purine metabolism tup01100   Metabolic pathways tup01522   Endocrine resistance tup04015   Rap1 signaling pathway tup04022   cGMP-PKG signaling pathway tup04024   cAMP signaling pathway tup04062   Chemokine signaling pathway tup04072   Phospholipase D signaling pathway tup04081   Hormone signaling tup04082   Neuroactive ligand signaling tup04114   Oocyte meiosis tup04211   Longevity regulating pathway tup04213   Longevity regulating pathway - multiple species tup04261   Adrenergic signaling in cardiomyocytes tup04270   Vascular smooth muscle contraction tup04371   Apelin signaling pathway tup04540   Gap junction tup04611   Platelet activation tup04713   Circadian entrainment tup04714   Thermogenesis tup04723   Retrograde endocannabinoid signaling tup04724   Glutamatergic synapse tup04725   Cholinergic synapse tup04726   Serotonergic synapse tup04727   GABAergic synapse tup04728   Dopaminergic synapse tup04750   Inflammatory mediator regulation of TRP channels tup04911   Insulin secretion tup04912   GnRH signaling pathway tup04913   Ovarian steroidogenesis tup04914   Progesterone-mediated oocyte maturation tup04915   Estrogen signaling pathway tup04916   Melanogenesis tup04918   Thyroid hormone synthesis tup04921   Oxytocin signaling pathway tup04923   Regulation of lipolysis in adipocytes tup04924   Renin secretion tup04925   Aldosterone synthesis and secretion tup04926   Relaxin signaling pathway tup04927   Cortisol synthesis and secretion tup04928   Parathyroid hormone synthesis, secretion and action tup04934   Cushing syndrome tup04935   Growth hormone synthesis, secretion and action tup04970   Salivary secretion tup04971   Gastric acid secretion tup04972   Pancreatic secretion tup04976   Bile secretion tup05012   Parkinson disease tup05030   Cocaine addiction tup05031   Amphetamine addiction tup05032   Morphine addiction tup05034   Alcoholism tup05163   Human cytomegalovirus infection tup05166   Human T-cell leukemia virus 1 infection tup05200   Pathways in cancer tup05207   Chemical carcinogenesis - receptor activation tup05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:tup00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102490639 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102490639 (ADCY5)    04371 Apelin signaling pathway     102490639 (ADCY5)    04072 Phospholipase D signaling pathway     102490639 (ADCY5)    04024 cAMP signaling pathway     102490639 (ADCY5)    04022 cGMP-PKG signaling pathway     102490639 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102490639 (ADCY5)    04081 Hormone signaling     102490639 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102490639 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     102490639 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102490639 (ADCY5)    04062 Chemokine signaling pathway     102490639 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     102490639 (ADCY5)    04923 Regulation of lipolysis in adipocytes     102490639 (ADCY5)    04912 GnRH signaling pathway     102490639 (ADCY5)    04913 Ovarian steroidogenesis     102490639 (ADCY5)    04915 Estrogen signaling pathway     102490639 (ADCY5)    04914 Progesterone-mediated oocyte maturation     102490639 (ADCY5)    04921 Oxytocin signaling pathway     102490639 (ADCY5)    04926 Relaxin signaling pathway     102490639 (ADCY5)    04935 Growth hormone synthesis, secretion and action     102490639 (ADCY5)    04918 Thyroid hormone synthesis     102490639 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     102490639 (ADCY5)    04916 Melanogenesis     102490639 (ADCY5)    04924 Renin secretion     102490639 (ADCY5)    04925 Aldosterone synthesis and secretion     102490639 (ADCY5)    04927 Cortisol synthesis and secretion     102490639 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102490639 (ADCY5)    04270 Vascular smooth muscle contraction     102490639 (ADCY5)   09154 Digestive system    04970 Salivary secretion     102490639 (ADCY5)    04971 Gastric acid secretion     102490639 (ADCY5)    04972 Pancreatic secretion     102490639 (ADCY5)    04976 Bile secretion     102490639 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     102490639 (ADCY5)    04727 GABAergic synapse     102490639 (ADCY5)    04725 Cholinergic synapse     102490639 (ADCY5)    04728 Dopaminergic synapse     102490639 (ADCY5)    04726 Serotonergic synapse     102490639 (ADCY5)    04723 Retrograde endocannabinoid signaling     102490639 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102490639 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     102490639 (ADCY5)    04213 Longevity regulating pathway - multiple species     102490639 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     102490639 (ADCY5)    04714 Thermogenesis     102490639 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102490639 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     102490639 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102490639 (ADCY5)    05163 Human cytomegalovirus infection     102490639 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     102490639 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     102490639 (ADCY5)    05031 Amphetamine addiction     102490639 (ADCY5)    05032 Morphine addiction     102490639 (ADCY5)    05034 Alcoholism     102490639 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102490639 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102490639 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102490639 (ADCY5) Enzymes [BR:tup01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102490639 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  102490639 NCBI-ProteinID:  XP_006154659 LinkDB All DBs Position Un AA seq 1088 aa AA seqDB search MPRCCAGPGAAPDCGDGGSSTGSGAGPGAVLSLGACCLALLQIFRSKKFPSDKLERLYQR YFFRLNQSSLTMLMAVLVLVCLVMLAFHAARPPLQLPYLAVLAAAVGVILVMAVLCNRAA FHQDHMGLACYALIAVVLAVQVVGLLLPQPRSASEGIWWTVFFIYTIYTLLPVRMRAAVL SGVLLSALHLAISLRTNAQDQFLLKQLVSNVLIFSCTNIVGVCTHYPAEVSQRQAFQETR ECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAKQEDMMFHKIYIQKHDNVSILF ADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLRIKILGDCYYCVSGLPEARAD HAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVHCGVLGLRKWQFDVWSNDVTLA NHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAYLKEHSIETFLILRCTQKRKEE KAMIAKMNRQRTNSIGHNPPPWGAERPFYNHLGGNQVSKEMKRMGFEDPKDNWFSVCFPE DEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEKKYSKQVDDRFGAYVACASLVFL FICFVQITIVPHSVFMLSVYLTCFLLLALVVSVSVIYSCVKLFPTPLQTLSRKIVRSKMN STLVGVFTITLVFLSAFVNMFMCNSTDLLGCLAEEHNLSVSQVNACHVVESVVNYSLGEE RGFCGSSWPNCNFPEYFTYSVLLSLLACSVFLQISCIGKLVLMLAIELIYVLVVEVPGVT LFDNADLLVTANAIDFNNNGTSQCPEHATKVALKVVTPIIISVFVLALYLHAQQVESTAR LDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAHFLARERRNDELYYQSCECVAVM FASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEDRFKQLEKIKTIGSTYMAAS GLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFNNFQMKIGLNIGPVVAGVIGARK PQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAANTYQLECRGVVKVKGKGEMMTYF LNGGPPLS NT seq 3267 nt NT seq  +upstreamnt  +downstreamnt atgccccgctgctgcgcagggcccggggccgcccccgactgcggggatggcggcagttcc actggctcaggcgcgggacccggcgcggtgctgtccctgggtgcctgctgcctggcgttg ctgcagatattccgctccaagaagttcccgtcggacaagctggagcggctgtaccagcgc tatttcttccgcctgaaccagagcagcctcaccatgctcatggccgtgctggtgctcgtg tgcctcgtcatgttggcctttcacgcggcgcggcccccgctgcagctgccctacctggcg gtgctggcggctgccgtgggtgtgatcctcgtcatggccgtgctctgcaaccgcgccgcc tttcaccaggaccacatgggcctggcctgctatgcgctcatcgccgtggtgctggccgtc caggtggtgggcctgctgctgccccagccgcgcagcgcttccgagggcatctggtggacc gtgttcttcatctacaccatctacacgctgctgcccgtgcgcatgcgggccgcagtgctc agcggggtgctcctgtctgccctccacctggccatctccctgcgcaccaacgcccaggac cagttcctgctcaagcagcttgtctccaacgtcctcatcttctcctgcaccaacatcgtg ggcgtctgcacccactaccctgccgaagtctcccagagacaggccttccaggagacccgg gaatgcatccaggcaagactccactcacagcgggagaaccagcagcaggagcggctcctg ctgtctgtccttccccgtcacgttgccatggagatgaaagcagacatcaacgccaagcag gaggatatgatgttccataagatttacatccagaagcatgacaacgtgagcatcctgttc gctgacatcgagggcttcaccagcctggcatcccagtgcactgctcaggaattggtcatg accctcaacgagctcttcgcccgcttcgacaagctggcagcggagaatcactgtttacgt attaagatcctgggggactgttattactgtgtctcggggctgcctgaagccagggctgac cacgcccactgctgcgtggagatgggcatggacatgatcgaggccatctcgttggtccgg gaggtgacaggggtgaacgtgaacatgcgcgtgggaattcacagcgggcgagtacactgc ggtgtccttggtctcaggaagtggcagttcgacgtctggtctaacgacgtcacactggcc aaccacatggaggccggcggcaaagcaggacgcatccacatcaccaaggccacactcaac tacctgaacggcgactacgaggtggagcccggctgcgggggtgagcgcaacgcctacctc aaggagcacagcattgagaccttcctcatcctgcgctgcacccagaagcggaaagaagag aaggccatgatcgccaagatgaaccgccagaggaccaactccattgggcacaacccacca ccctggggcgccgagcgccccttctacaaccacctgggcggcaaccaggtgtcaaaggag atgaagcgcatgggttttgaagaccccaaggacaactggttttctgtctgtttccccgag gatgaagtggatgagtttctgggccgggccatcgatgccaggagcattgacaggctgcga tctgagcacgtccgcaaattcctcctgaccttcagggagcctgacttagagaagaagtac tccaagcaggtggatgaccgattcggtgcctacgtggcgtgtgcctcgctcgtcttcctc ttcatctgctttgtccagatcaccatcgtgccccactccgtgttcatgctgagtgtctat ctgacctgcttcctgctgctggccctggtggtgtccgtgtctgtcatctactcctgcgtg aagctcttccccaccccactgcagaccctctccaggaagattgtgcggtccaagatgaac agcaccctggttggggtcttcaccatcaccctggtgttcctgtcggcctttgtcaacatg ttcatgtgcaactccacggacctgctgggctgcctcgcagaggagcacaacctcagcgtg agccaggtcaacgcgtgccacgtggtggagtcggtggtcaactacagcctgggcgaggag cggggcttctgtggcagctcctggcccaactgcaacttccctgagtacttcacctacagc gtgctgctcagcctgctggcctgctccgtgttcctgcagatcagctgcatcgggaagctg gtgctcatgctggccatcgagctcatttacgtgctagtcgttgaagtgcccggcgtcacg ctcttcgataacgccgacctgctggtcaccgccaatgccatagacttcaacaacaacggg acctcccagtgccctgagcatgcgaccaaggtggcgctgaaggtggtgacgcccatcatc atctcggtctttgtgctggccctgtacctgcatgcccagcaggtggagtccactgcccgc ctcgacttcctctggaaactgcaggccacggaggagaaggaggagatggaggagctgcag gcctacaaccggcgcctgctgcacaacatcctgcccaaggacgtggccgcccacttcctg gcccgcgagcggcgcaacgacgagctgtactaccagtcctgcgagtgcgtggccgtcatg ttcgcctccatcgccaacttctccgagttctacgtggagctggaggccaacaacgagggc gttgagtgcctgcggctgctcaacgagatcatcgccgacttcgatgagatcatcagtgag gatcggttcaagcagctggagaagatcaagaccattggcagcacctacatggccgcctcg ggcctcaacgactccacctacgacaaggtgggcaagacccacatcaaggctctggccgac tttgccatgaagctgatggaccagatgaagtacatcaacgagcactccttcaacaacttc cagatgaagatcgggctcaacatcggccctgtggtggccggggtgattggggcccgcaag ccccagtacgacatctggggcaataccgtgaacgtggccagccgcatggacagcactggt gtgcccgaccgtatccaggtcaccacggacatgtaccaggtgctggctgccaacacatac cagctggagtgccgaggcgtggtcaaagtcaagggcaagggcgagatgatgacctacttc ctcaatggagggcccccgctcagttag

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