Tupaia chinensis (Chinese tree shrew): 102490996 Help Entry 102490996         CDS       T02978                                  Name (RefSeq) interleukin-6   KO K05405   interleukin 6 Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup01521   EGFR tyrosine kinase inhibitor resistance tup01523   Antifolate resistance tup04060   Cytokine-cytokine receptor interaction tup04061   Viral protein interaction with cytokine and cytokine receptor tup04066   HIF-1 signaling pathway tup04068   FoxO signaling pathway tup04151   PI3K-Akt signaling pathway tup04218   Cellular senescence tup04620   Toll-like receptor signaling pathway tup04621   NOD-like receptor signaling pathway tup04623   Cytosolic DNA-sensing pathway tup04625   C-type lectin receptor signaling pathway tup04630   JAK-STAT signaling pathway tup04640   Hematopoietic cell lineage tup04657   IL-17 signaling pathway tup04659   Th17 cell differentiation tup04668   TNF signaling pathway tup04672   Intestinal immune network for IgA production tup04931   Insulin resistance tup04932   Non-alcoholic fatty liver disease tup04933   AGE-RAGE signaling pathway in diabetic complications tup04936   Alcoholic liver disease tup05010   Alzheimer disease tup05020   Prion disease tup05022   Pathways of neurodegeneration - multiple diseases tup05132   Salmonella infection tup05133   Pertussis tup05134   Legionellosis tup05135   Yersinia infection tup05142   Chagas disease tup05143   African trypanosomiasis tup05144   Malaria tup05146   Amoebiasis tup05152   Tuberculosis tup05161   Hepatitis B tup05162   Measles tup05163   Human cytomegalovirus infection tup05164   Influenza A tup05166   Human T-cell leukemia virus 1 infection tup05167   Kaposi sarcoma-associated herpesvirus infection tup05168   Herpes simplex virus 1 infection tup05169   Epstein-Barr virus infection tup05171   Coronavirus disease - COVID-19 tup05200   Pathways in cancer tup05202   Transcriptional misregulation in cancer tup05321   Inflammatory bowel disease tup05323   Rheumatoid arthritis tup05332   Graft-versus-host disease tup05410   Hypertrophic cardiomyopathy tup05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102490996    04668 TNF signaling pathway     102490996    04066 HIF-1 signaling pathway     102490996    04068 FoxO signaling pathway     102490996    04151 PI3K-Akt signaling pathway     102490996   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     102490996    04061 Viral protein interaction with cytokine and cytokine receptor     102490996  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     102490996  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     102490996    04620 Toll-like receptor signaling pathway     102490996    04621 NOD-like receptor signaling pathway     102490996    04623 Cytosolic DNA-sensing pathway     102490996    04625 C-type lectin receptor signaling pathway     102490996    04659 Th17 cell differentiation     102490996    04657 IL-17 signaling pathway     102490996    04672 Intestinal immune network for IgA production     102490996  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102490996    05202 Transcriptional misregulation in cancer     102490996   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102490996    05161 Hepatitis B     102490996    05171 Coronavirus disease - COVID-19     102490996    05164 Influenza A     102490996    05162 Measles     102490996    05168 Herpes simplex virus 1 infection     102490996    05163 Human cytomegalovirus infection     102490996    05167 Kaposi sarcoma-associated herpesvirus infection     102490996    05169 Epstein-Barr virus infection     102490996   09171 Infectious disease: bacterial    05132 Salmonella infection     102490996    05135 Yersinia infection     102490996    05133 Pertussis     102490996    05134 Legionellosis     102490996    05152 Tuberculosis     102490996   09174 Infectious disease: parasitic    05146 Amoebiasis     102490996    05144 Malaria     102490996    05142 Chagas disease     102490996    05143 African trypanosomiasis     102490996   09163 Immune disease    05323 Rheumatoid arthritis     102490996    05321 Inflammatory bowel disease     102490996    05332 Graft-versus-host disease     102490996   09164 Neurodegenerative disease    05010 Alzheimer disease     102490996    05020 Prion disease     102490996    05022 Pathways of neurodegeneration - multiple diseases     102490996   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102490996    05410 Hypertrophic cardiomyopathy     102490996   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102490996    04932 Non-alcoholic fatty liver disease     102490996    04931 Insulin resistance     102490996    04933 AGE-RAGE signaling pathway in diabetic complications     102490996   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102490996    01523 Antifolate resistance     102490996  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:tup04052]     102490996 Cytokines and neuropeptides [BR:tup04052]  Cytokines   Interleukins    102490996 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL6 Motif Other DBs NCBI-GeneID:  102490996 NCBI-ProteinID:  XP_006146753 LinkDB All DBs Position Un AA seq 280 aa AA seqDB search MSKVQSMLQLTESKILHLPTRKPAMTSLSTRKGALSLAVFFLGLSLMMATADPTIPAPSN TEEIIYKMFYHINLMKNEFGEPTNVCKAKMLPAKSNLNIPLLERKDGCVHIGFNKETCLR RINNGLQEFQVYLEFLEKNLNDTDNVRSVQIYSRALMRTLMSPTTVTSPSPDANASLLEK MQAQDKSMRTETARLILCRLDKFLQYAMRASRINQLHGPDFGLIIIPAYSTTNSYYGRKM MDGKAGEEKPEKLQLTGATGVMEGKVPVTALISNQLKKKV NT seq 843 nt NT seq  +upstreamnt  +downstreamnt atgtctaaggttcaatctatgcttcaactcaccgagagcaaaatacttcatctgcccacc aggaaaccagctatgacttcgctatctacccgaaaaggtgccttaagtctagctgtcttc ttcctgggcctgtcactaatgatggctactgctgatcccaccattccagctccaagtaac actgaagaaataatttacaagatgttctaccatatcaatttaatgaaaaacgagtttggt gagccgactaatgtctgtaaagccaagatgctaccagcaaaaagcaatctgaacattccc ctgctggagaggaaggatgggtgtgtccatattggatttaataaggagacatgcctgagg agaatcaacaatggtcttcaggagtttcaggtatacctagagttcctagagaaaaatctg aatgatacagataatgtgagaagtgtgcagatttattccagagcattgatgcgaacgtta atgtctccgactacagtaacctctcctagtcccgatgcaaatgccagcctgctggagaag atgcaggcacaggacaagtcaatgagaacagaaacagctcgcctcatcctgtgcagactt gataagtttctacagtacgctatgagggcttctcggataaaccagttgcatggacctgat tttgggcttataatcatccctgcctattccaccaccaatagctactatggaaggaaaatg atggacgggaaggcgggagaggagaagcctgaaaagctgcaactaactggagccaccgga gtaatggaggggaaagttccagtcacagcgctgataagcaatcagctgaagaagaaggtg tag

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