Tupaia chinensis (Chinese tree shrew): 102495244
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Entry
102495244 CDS
T02978
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup01524
Platinum drug resistance
tup04010
MAPK signaling pathway
tup04071
Sphingolipid signaling pathway
tup04141
Protein processing in endoplasmic reticulum
tup04210
Apoptosis
tup04530
Tight junction
tup04668
TNF signaling pathway
tup04714
Thermogenesis
tup04722
Neurotrophin signaling pathway
tup04932
Non-alcoholic fatty liver disease
tup04936
Alcoholic liver disease
tup05010
Alzheimer disease
tup05012
Parkinson disease
tup05014
Amyotrophic lateral sclerosis
tup05016
Huntington disease
tup05017
Spinocerebellar ataxia
tup05022
Pathways of neurodegeneration - multiple diseases
tup05208
Chemical carcinogenesis - reactive oxygen species
tup05417
Lipid and atherosclerosis
tup05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
102495244 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102495244 (MAP3K5)
04668 TNF signaling pathway
102495244 (MAP3K5)
04071 Sphingolipid signaling pathway
102495244 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
102495244 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
102495244 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
102495244 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
102495244 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
102495244 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
102495244 (MAP3K5)
05012 Parkinson disease
102495244 (MAP3K5)
05014 Amyotrophic lateral sclerosis
102495244 (MAP3K5)
05016 Huntington disease
102495244 (MAP3K5)
05017 Spinocerebellar ataxia
102495244 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
102495244 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
102495244 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
102495244 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
102495244 (MAP3K5)
04932 Non-alcoholic fatty liver disease
102495244 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
102495244 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tup01001
]
102495244 (MAP3K5)
Enzymes [BR:
tup01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
102495244 (MAP3K5)
Protein kinases [BR:
tup01001
]
Serine/threonine kinases: STE group
STE11 family
102495244 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
102495244
NCBI-ProteinID:
XP_006144438
LinkDB
All DBs
Position
Un
AA seq
1298 aa
AA seq
DB search
MKGNCRRGGSGGGRRTTVAYVISEASQGQLVVSESEALQSLREACETVGATLETLHFGKL
DFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDTNSDSLQSL
KEIICQKNTMCTGNYTFVPYMVTPHNKVYCCDSSFMKGLTELMQPNFELLLGPICLPLVD
RFVQLLKVAQASSSQYFRESILSDIRKARNLYTGKELAAELARIRQRVDNIEVLTADIVI
NLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDRAKALDIM
IPMVQSEGQVASDMYCLVGRIYKDMFLDSNFTDTESRDHGASWFKKAFESEPTLQSGINY
AVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLANDHMRVI
QASEKLFKLKTPAWYLKSIVETILIYKHFVKLPTEQPVAKQELVDFWMDFLVEATKTDVT
VVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASSVRGVSIS
KFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRNTEEGDCEGDSLEYDY
EYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIALHKHLKHK
NIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQILEGLKYLH
DNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAPEIIDKGP
RGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMSAEAKAFI
LKCFEPDPDKRACANDLLMDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLPVPVLVED
TSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDVKGIRTLFLGIPDENFEDHSAPPSPE
EKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGSEEPKLKWEHITTLVASLR
EFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIKPHWMFAL
DSIIRKAVQTAITILVPELRPHFSIASESDTADQEDLDIDDHEEQPSNQTVRRPQAVIED
AVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEELVRKERELQALLHQAIEE
KDQEIKHLKLKSQPIDIPGVPVCHLNSPRTNTEDSELTDWLRENGADEDTISRFLAEDYT
LVDVLYYVTRDDLKCLRLRGGMLCTLWKAIVDFRDKQT
NT seq
3897 nt
NT seq
+upstream
nt +downstream
nt
atgaagggaaactgccgccggggaggaagcgggggcggccgacggaccacggtggcatat
gtgatcagcgaagcgagccaagggcagctggtggtgtccgagagcgaggccctgcagagc
ctgcgggaggcgtgcgaaacggtgggcgccaccctggagacgctgcattttggtaaactg
gactttggggaaaccacggtgctggatcgtttttacaatgcagatattgctgtggtggaa
atgagtgatgccttccggcagccgtctttgttttaccaccttggggtgcgagaaagcttc
agcatggccaacaacatcatcctatactgtgataccaactcggactctctgcagtcactg
aaggaaatcatttgccagaagaatactatgtgcactgggaactacacctttgttccttac
atggtcacgccacataataaggtctactgctgtgacagcagcttcatgaaggggttgaca
gagctcatgcagcccaactttgagctgcttcttgggcccatctgcttacctcttgtggat
cgttttgttcaacttctgaaggtggcacaagcaagttccagccagtatttccgagaatct
atactcagtgatatcagaaaagctcggaatttatacactggtaaagaattggcagctgaa
ttggccagaattcgacaacgagtagacaatatagaagtcttgacagcagatattgtcata
aatctgttactttcctacagagatatccaggactatgattctattgtgaagctggtagag
actttagaaaaactgccaacctttgacttggcctcccatcaccatgtgaagtttcattat
gcctttgcactgaacaggagaaatctccctggagatagagcaaaagctcttgatattatg
atccccatggtacaaagtgaagggcaagttgcttcagatatgtattgcctagttggtcgg
atctacaaagatatgtttttggactctaattttacagacactgaaagtagagaccatgga
gcttcttggttcaaaaaggcatttgaatctgagccaacactacagtcaggaattaattat
gcggtcctcctcttggcagcagggcaccaatttgaatcttcctttgagctccggaaagtt
ggggtgaagctaagtagccttcttggtaaaaaaggaaacttggaaaaacttcagagctac
tgggaagttggattttttctgggggccagtgtcctggccaatgaccacatgagagtcatt
caagcatctgaaaagctttttaaactgaagacaccagcatggtacctcaagtctatcgta
gagacaattttgatatataagcattttgtgaaactgcctacagaacagcccgtggccaag
caggaactcgtggacttttggatggattttctggttgaagccacaaagacagatgttaca
gtagttaggtttccagtattaatattagaaccaactaaaatctatcaaccctcttatttg
tctatcaacaatgaagtcgaggaaaagacaatatccatttggcatgtgcttcctgatgac
aagaaaggtatacatgagtggaattttagtgcctcttctgtaaggggagtgagtatttct
aaatttgaagaacgatgctgtttcctttatgtgcttcacaactctgatgattttcaaatc
tatttttgtacagaactccattgtaaaaagttttttgaaatggtgaacaccattactgaa
gagaaggggagaaacacagaagaaggagactgtgaaggtgactccctggagtatgactat
gaatatgatgaaaatggtgacagagtcgtcctaggaaaaggcacatacgggatagtctac
gcgggtcgagacttgagcaaccaagtcagaattgctattaaagaaatcccagagagagat
agcagatactctcagcccctacatgaagaaatagcattgcataagcatctgaagcacaaa
aatattgtccagtatctgggctctttcagtgagaatggtttcattaaaatcttcatggag
caggtcccaggaggaagtctttctgctcttctgcgttccaaatggggcccgttaaaagac
aatgagcaaacgattggcttttatacaaagcaaatactggaaggattaaaatacctccat
gataatcagatagtgcaccgtgatataaagggtgacaacgtgttgataaatacctacagt
ggtgttcttaagatctctgacttcgggacatcaaagagacttgctggcatcaacccgtgt
actgaaacttttactggtactcttcagtacatggccccagaaataatagacaaaggaccg
agagggtatggaaaagcagcggacatttggtctttgggctgcacaatcatcgagatggcc
acgggaaaaccaccattttatgaactaggagaaccccaagcagcaatgttcaaggtggga
atgttcaaagtccaccccgagatccctgagtccatgtctgcagaggccaaggcgttcata
ctgaaatgttttgaaccagaccccgacaagagagcctgtgccaacgacttgcttatggat
gagttcttaaaagtttcaagcaaaaagaaaaagacacaacctaagctttcagctctttca
gctggatcaaatgagtatctcaggagcatctccttgcccgtgcccgtcctggtggaggac
accagcagcagcagcgagtatggctcggtctcacccgacacggagctgaaggtggacccc
ttctctttcaaaacaagagccaagtcctgtggagaaaaagatgtaaaaggaatacggaca
ctctttttgggcattccagatgagaattttgaagaccacagcgcacccccttcccctgaa
gagaaggattctggattcttcatgctcaggaaggacagtgagaggcgagccacccttcac
aggatcctgactgaagaccaagacaaagttgtgaggaacttgatggaatcattagctcag
gggtctgaagaaccgaaactgaagtgggagcacatcacaacccttgttgcaagcctccga
gaatttgtaagatccacggaccgaaaaatcattgccaccacactgtccaagctgaaattg
gagctggacttcgacagccacggcattagccaagtgcaggtggttctctttggttttcaa
gatgctgtcaacaaagtgcttcggaatcataacatcaagccacactggatgtttgcctta
gacagtattatccgcaaggcagtacagacggctatcaccattctggttccagaactgagg
ccacattttagcattgcatctgagagtgacaccgcggatcaagaagacctggatatagat
gaccacgaggaacagccttccaatcaaactgtccgaagacctcaagctgtcattgaagat
gccgtggctacctcaggggtgagcacactcagttctactgtatcgcacgattcccagagt
gctcaccgatcactgaacgtacagcttggaaggatgaaaatagaaacaaatagattacta
gaagaattggttcggaaagagagagaattacaagcactccttcatcaagctattgaagaa
aaagaccaagaaattaaacatctgaagcttaagtcacaaccaatagatattcctggggta
ccagtgtgtcacctaaattctcctcgcacaaatactgaggattctgaacttactgactgg
ctgagagaaaatggagctgatgaagacactataagtcggtttctggctgaggattacaca
ctagtggatgttctctactatgtgacacgtgatgatctaaagtgcctgagactaaggggc
ggtatgctgtgcacactgtggaaggccattgttgactttcgagacaaacagacttga
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integrated database retrieval system
