KEGG   Tupaia chinensis (Chinese tree shrew): 102495430
Entry
102495430         CDS       T02978                                 
Symbol
PAK1
Name
(RefSeq) p21 (RAC1) activated kinase 1
  KO
K04409  p21-activated kinase 1 [EC:2.7.11.1]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup04010  MAPK signaling pathway
tup04012  ErbB signaling pathway
tup04014  Ras signaling pathway
tup04024  cAMP signaling pathway
tup04062  Chemokine signaling pathway
tup04360  Axon guidance
tup04392  Hippo signaling pathway - multiple species
tup04510  Focal adhesion
tup04625  C-type lectin receptor signaling pathway
tup04650  Natural killer cell mediated cytotoxicity
tup04660  T cell receptor signaling pathway
tup04666  Fc gamma R-mediated phagocytosis
tup04810  Regulation of actin cytoskeleton
tup05132  Salmonella infection
tup05170  Human immunodeficiency virus 1 infection
tup05205  Proteoglycans in cancer
tup05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:tup00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102495430 (PAK1)
   04012 ErbB signaling pathway
    102495430 (PAK1)
   04014 Ras signaling pathway
    102495430 (PAK1)
   04392 Hippo signaling pathway - multiple species
    102495430 (PAK1)
   04024 cAMP signaling pathway
    102495430 (PAK1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102495430 (PAK1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102495430 (PAK1)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    102495430 (PAK1)
   04650 Natural killer cell mediated cytotoxicity
    102495430 (PAK1)
   04660 T cell receptor signaling pathway
    102495430 (PAK1)
   04666 Fc gamma R-mediated phagocytosis
    102495430 (PAK1)
   04062 Chemokine signaling pathway
    102495430 (PAK1)
  09158 Development and regeneration
   04360 Axon guidance
    102495430 (PAK1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102495430 (PAK1)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    102495430 (PAK1)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    102495430 (PAK1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    102495430 (PAK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tup01001]
    102495430 (PAK1)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tup04131]
    102495430 (PAK1)
   03036 Chromosome and associated proteins [BR:tup03036]
    102495430 (PAK1)
Enzymes [BR:tup01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102495430 (PAK1)
Protein kinases [BR:tup01001]
 Serine/threonine kinases: STE group
  STE20 family
   102495430 (PAK1)
Membrane trafficking [BR:tup04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    102495430 (PAK1)
 Endocytosis
  Macropinocytosis
   Kinases
    102495430 (PAK1)
Chromosome and associated proteins [BR:tup03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     102495430 (PAK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal APH DSHCT
Other DBs
NCBI-GeneID: 102495430
NCBI-ProteinID: XP_006150037
LinkDB
Position
Un
AA seq 544 aa
MSNNGLDIQDKPPAPPMRNTSTMIGAGSKDAGALNHGSKPLPPNPEEKKKKDRFYRSILP
GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN
PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKAVSETPAVPPVSEDEDDD
DDAAPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENTTTPPDALTRNTEK
QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM
NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM
DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR
STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT
PELQNPEKLSSIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT
KNNH
NT seq 1635 nt   +upstreamnt  +downstreamnt
atgtcaaataacggcctagacattcaagacaaacccccagcccctccaatgagaaacacc
agcactatgattggagctggcagcaaagatgctggagccctaaaccacggttccaaacct
ctgcctccaaacccagaggagaagaagaaaaaggaccgattttaccgatccatcttacca
ggagataaaacaaataaaaagaaggagaaggagcggccagagatctcccttccttcagat
tttgaacacacaattcatgtcggttttgatgctgtcacgggggaatttacagggatgcca
gagcagtgggcccgtttgcttcagacatcaaatatcaccaagtcggagcagaagaaaaac
ccacaggctgtcctggacgtgttggaattctacaactcaaaaaagacttccaatagccag
aagtacatgagcttcacagataagtcagctgaggattataattcttctaacactttgaac
gtgaaggctgtgtctgagacccccgcggtgccgccagtttcagaagatgaagatgatgac
gacgacgctgccccaccgcccgtgattgctccgcgccccgagcacacaaagtctgtctat
acgcggtctgtgatcgagccacttcctgttactcccactcgggatgtagccacatctccc
atttctcccaccgagaataccaccactccaccagacgctttgacccggaatactgagaag
cagaagaagaagcccaaaatgtctgatgaggagatcttggagaaattacggagcatagtg
agtgtgggcgatcctaagaagaaatatacacggtttgagaagattggacaaggtgcttcg
ggcactgtgtacactgcaatggacgtggccacaggacaggaggtggccattaagcagatg
aatcttcagcagcagccgaagaaagagctgattattaatgagattctggtcatgagggaa
aacaagaacccaaacattgtgaactacttggacagttaccttgtgggagatgagctgtgg
gttgtcatggaatacttggctggaggctccttgacagacgtggtgacagaaacctgcatg
gatgaaggccagattgcagctgtgtgccgggagtgtttgcaggctctggagtttctgcat
tcaaaccaggtcattcacagagacatcaagagtgacaatattctgttgggaatggatggc
tctgtcaagctaactgattttggattctgtgcacagataaccccagagcagagtaaacgg
agcaccatggtgggaaccccatactggatggcgccagaggttgtcacacggaaggcctat
gggcccaaggttgatatctggtccttgggcatcatggccatcgaaatgattgaaggggaa
cccccttacctcaatgaaaaccctctgagagccttgtacctcattgccaccaacgggacc
ccggagcttcagaacccagagaagctgtcatctatcttccgggactttctgaaccgttgt
cttgagatggacgtggagaagaggggttcagctaaagagctgcttcagcatcagttcctg
aagattgccaagcctctctccagcctgacaccactgattgccgcagcaaaggaggcaacc
aagaacaatcactag

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