Tupaia chinensis (Chinese tree shrew): 102496137 Help Entry 102496137         CDS       T02978                                  Symbol IL6 Name (RefSeq) interleukin-6   KO K05405   interleukin 6 Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup01521   EGFR tyrosine kinase inhibitor resistance tup01523   Antifolate resistance tup04060   Cytokine-cytokine receptor interaction tup04061   Viral protein interaction with cytokine and cytokine receptor tup04066   HIF-1 signaling pathway tup04068   FoxO signaling pathway tup04151   PI3K-Akt signaling pathway tup04218   Cellular senescence tup04620   Toll-like receptor signaling pathway tup04621   NOD-like receptor signaling pathway tup04623   Cytosolic DNA-sensing pathway tup04625   C-type lectin receptor signaling pathway tup04630   JAK-STAT signaling pathway tup04640   Hematopoietic cell lineage tup04657   IL-17 signaling pathway tup04659   Th17 cell differentiation tup04668   TNF signaling pathway tup04672   Intestinal immune network for IgA production tup04931   Insulin resistance tup04932   Non-alcoholic fatty liver disease tup04933   AGE-RAGE signaling pathway in diabetic complications tup04936   Alcoholic liver disease tup05010   Alzheimer disease tup05020   Prion disease tup05022   Pathways of neurodegeneration - multiple diseases tup05132   Salmonella infection tup05133   Pertussis tup05134   Legionellosis tup05135   Yersinia infection tup05142   Chagas disease tup05143   African trypanosomiasis tup05144   Malaria tup05146   Amoebiasis tup05152   Tuberculosis tup05161   Hepatitis B tup05162   Measles tup05163   Human cytomegalovirus infection tup05164   Influenza A tup05166   Human T-cell leukemia virus 1 infection tup05167   Kaposi sarcoma-associated herpesvirus infection tup05168   Herpes simplex virus 1 infection tup05169   Epstein-Barr virus infection tup05171   Coronavirus disease - COVID-19 tup05200   Pathways in cancer tup05202   Transcriptional misregulation in cancer tup05321   Inflammatory bowel disease tup05323   Rheumatoid arthritis tup05332   Graft-versus-host disease tup05410   Hypertrophic cardiomyopathy tup05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     102496137 (IL6)    04668 TNF signaling pathway     102496137 (IL6)    04066 HIF-1 signaling pathway     102496137 (IL6)    04068 FoxO signaling pathway     102496137 (IL6)    04151 PI3K-Akt signaling pathway     102496137 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     102496137 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     102496137 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     102496137 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     102496137 (IL6)    04620 Toll-like receptor signaling pathway     102496137 (IL6)    04621 NOD-like receptor signaling pathway     102496137 (IL6)    04623 Cytosolic DNA-sensing pathway     102496137 (IL6)    04625 C-type lectin receptor signaling pathway     102496137 (IL6)    04659 Th17 cell differentiation     102496137 (IL6)    04657 IL-17 signaling pathway     102496137 (IL6)    04672 Intestinal immune network for IgA production     102496137 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102496137 (IL6)    05202 Transcriptional misregulation in cancer     102496137 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102496137 (IL6)    05161 Hepatitis B     102496137 (IL6)    05171 Coronavirus disease - COVID-19     102496137 (IL6)    05164 Influenza A     102496137 (IL6)    05162 Measles     102496137 (IL6)    05168 Herpes simplex virus 1 infection     102496137 (IL6)    05163 Human cytomegalovirus infection     102496137 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     102496137 (IL6)    05169 Epstein-Barr virus infection     102496137 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     102496137 (IL6)    05135 Yersinia infection     102496137 (IL6)    05133 Pertussis     102496137 (IL6)    05134 Legionellosis     102496137 (IL6)    05152 Tuberculosis     102496137 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     102496137 (IL6)    05144 Malaria     102496137 (IL6)    05142 Chagas disease     102496137 (IL6)    05143 African trypanosomiasis     102496137 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     102496137 (IL6)    05321 Inflammatory bowel disease     102496137 (IL6)    05332 Graft-versus-host disease     102496137 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     102496137 (IL6)    05020 Prion disease     102496137 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     102496137 (IL6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102496137 (IL6)    05410 Hypertrophic cardiomyopathy     102496137 (IL6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102496137 (IL6)    04932 Non-alcoholic fatty liver disease     102496137 (IL6)    04931 Insulin resistance     102496137 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     102496137 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102496137 (IL6)    01523 Antifolate resistance     102496137 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:tup04052]     102496137 (IL6) Cytokines and neuropeptides [BR:tup04052]  Cytokines   Interleukins    102496137 (IL6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL6 IL23 Motif Other DBs NCBI-GeneID:  102496137 NCBI-ProteinID:  XP_006169903 LinkDB All DBs Position Un AA seq 208 aa AA seqDB search MTSLSTSTFSPVAFSLGLLLVMATALPTPVLLGEDSQDGAILNIPEPTSTDKTEDLAKYI LEEINVLKQEACDSIYKCRVALAKNNLNLPKMAEKDGCFHNGFNKDTCLMRIITGLLEFQ VYIEFLKNNVNEKSSARAVQIGTKALMLMLKQKETYPSIVPTPDPTSNASLMVKMQSQEE WLKKVTVRLILRSLEDFLQYTVRASRLM NT seq 627 nt NT seq  +upstreamnt  +downstreamnt atgacctccttgtccacaagcaccttcagtccagttgccttctccctggggctgctccta gtgatggctactgctcttcccacaccagttctcctgggagaagattcccaagatggtgcc attctaaatataccagaacccacctccacagataaaactgaagatctcgctaagtacatc cttgaagaaatcaatgtactgaaacaagaggcatgtgacagtatttacaagtgcagggtt gcactggcaaaaaacaatctgaaccttccaaagatggcagaaaaagatggatgcttccat aatggatttaataaggatacttgcctgatgagaatcatcactggtcttttggagtttcag gtatatatagagtttctcaagaacaatgttaatgaaaagagcagtgccagagctgtgcag attggtaccaaagccctgatgctgatgctgaagcaaaaggaaacgtatccaagtatagtt cccacccctgacccaacttcaaatgccagcttgatggtgaagatgcagtctcaagaggag tggctaaagaaggtgacagtccgactcatcctgcgcagcctggaggatttcctgcagtat actgtgagggcttctcggctaatgtag

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