Tupaia chinensis (Chinese tree shrew): 102498355 Help Entry 102498355         CDS       T02978                                  Symbol CASP8, Caspase-8 Name (RefSeq) caspase 8   KO K04398   caspase 8 [EC:3.4.22.61] Organism tup  Tupaia chinensis (Chinese tree shrew) Pathway tup01524   Platinum drug resistance tup04115   p53 signaling pathway tup04210   Apoptosis tup04215   Apoptosis - multiple species tup04217   Necroptosis tup04620   Toll-like receptor signaling pathway tup04621   NOD-like receptor signaling pathway tup04622   RIG-I-like receptor signaling pathway tup04623   Cytosolic DNA-sensing pathway tup04625   C-type lectin receptor signaling pathway tup04657   IL-17 signaling pathway tup04668   TNF signaling pathway tup04932   Non-alcoholic fatty liver disease tup04936   Alcoholic liver disease tup05010   Alzheimer disease tup05016   Huntington disease tup05022   Pathways of neurodegeneration - multiple diseases tup05132   Salmonella infection tup05134   Legionellosis tup05142   Chagas disease tup05145   Toxoplasmosis tup05152   Tuberculosis tup05160   Hepatitis C tup05161   Hepatitis B tup05162   Measles tup05163   Human cytomegalovirus infection tup05164   Influenza A tup05165   Human papillomavirus infection tup05167   Kaposi sarcoma-associated herpesvirus infection tup05168   Herpes simplex virus 1 infection tup05169   Epstein-Barr virus infection tup05170   Human immunodeficiency virus 1 infection tup05200   Pathways in cancer tup05203   Viral carcinogenesis tup05416   Viral myocarditis tup05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:tup00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     102498355 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     102498355 (CASP8)    04215 Apoptosis - multiple species     102498355 (CASP8)    04217 Necroptosis     102498355 (CASP8)    04115 p53 signaling pathway     102498355 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     102498355 (CASP8)    04621 NOD-like receptor signaling pathway     102498355 (CASP8)    04622 RIG-I-like receptor signaling pathway     102498355 (CASP8)    04623 Cytosolic DNA-sensing pathway     102498355 (CASP8)    04625 C-type lectin receptor signaling pathway     102498355 (CASP8)    04657 IL-17 signaling pathway     102498355 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102498355 (CASP8)    05203 Viral carcinogenesis     102498355 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102498355 (CASP8)    05161 Hepatitis B     102498355 (CASP8)    05160 Hepatitis C     102498355 (CASP8)    05164 Influenza A     102498355 (CASP8)    05162 Measles     102498355 (CASP8)    05168 Herpes simplex virus 1 infection     102498355 (CASP8)    05163 Human cytomegalovirus infection     102498355 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     102498355 (CASP8)    05169 Epstein-Barr virus infection     102498355 (CASP8)    05165 Human papillomavirus infection     102498355 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     102498355 (CASP8)    05134 Legionellosis     102498355 (CASP8)    05152 Tuberculosis     102498355 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     102498355 (CASP8)    05142 Chagas disease     102498355 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     102498355 (CASP8)    05016 Huntington disease     102498355 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     102498355 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102498355 (CASP8)    05416 Viral myocarditis     102498355 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     102498355 (CASP8)    04932 Non-alcoholic fatty liver disease     102498355 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     102498355 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:tup01002]     102498355 (CASP8) Enzymes [BR:tup01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      102498355 (CASP8) Peptidases and inhibitors [BR:tup01002]  Cysteine peptidases   Family C14: caspase family    102498355 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  102498355 NCBI-ProteinID:  XP_006153097 LinkDB All DBs Position Un AA seq 497 aa AA seqDB search MVLGKGEQVSNTSSYLLTRMDFNLCLYEIGEQLESDELASLKFLSLDYIPHKKQEPIRDA LSLFQTLQEKRMLEESNLSFLKELLFQINRVDLLTRCLNTSKEEMERELQIPGRAQISAY RVMLFQIAEDVTKLELRSFKFFLRQEISKCKLDDDMSLLDIFVEMEKRVILGERNLDVLK RICDQINKSLLLKIRDYEELSRERRGSLERSADGPSNGEGPSGMLAMADSSREQDSESQT LDKVYRMKSKPRGYCLIFNNHNFSQARMEVPKHQSIKDRNGTDVDAEALDKTFSELHFEI VHYKDCTAKNICDILKFYQRKNHNSKDCFVCCILSHGDKGIVYGTDGQEASIYELTSYFT GSKCPSLAGKPKVFFIQACQGDNYHKGVPYETDSEEREAYLEMDSPERRYIPDEADFLLG MATVNNCVSYRSTVEGSWYIQSLCQSLRERCPRGDDILTILTEVNYDVSNKDDRIHKGKQ MPQPTFTLRKKLYFSLH NT seq 1494 nt NT seq  +upstreamnt  +downstreamnt atggtgctggggaagggagagcaggtttctaatacatcctcctacctcttgacgagaatg gattttaatctatgtctgtatgaaattggggagcaactggaaagtgatgaactggcctcc ctcaagttcctgagcctggactacatccctcataagaagcaggaacccatccgggatgcc ctaagtttgtttcagacactccaggaaaagaggatgttggaggaaagcaatctgtccttc ttgaaggagttgcttttccaaattaatagagtggatctgctgaccagatgcttaaacact agcaaggaggagatggagagagagcttcagatcccaggcagggctcagatttctgcctac agggtcatgctttttcagattgcagaagatgtcaccaaactggaattacgttcttttaag ttttttttgaggcaggagatctccaaatgtaaactggatgatgacatgagcttgcttgat atttttgtagagatggagaagagagtcatcctaggggaaagaaatctggacgtcctaaaa agaatctgcgaccaaatcaacaagagcctgctgttgaaaatccgtgattatgaagaatta agcagagagagaagagggagccttgaaaggagtgcagatggaccttcaaatggggagggg ccatctggaatgctggcaatggcggattcttctagagaacaagacagtgagtcacagaca ttggacaaggtttatcgaatgaaaagtaaacctcggggctactgtctgatcttcaacaat cacaattttagccaagcacgtatggaggtacccaaacatcagagcattaaggacaggaat ggaacagacgtggatgcagaggctttagacaagaccttcagtgaacttcattttgagata gtacattacaaagactgcactgctaaaaatatctgtgatattttgaaattctaccaacgc aagaatcacaatagcaaggattgcttcgtctgctgtatcctctcccatggagacaagggc attgtctacggcactgatggacaggaggcctccatatatgagctgacctcttattttact ggttccaagtgcccttcccttgctgggaaacccaaagtcttttttattcaggcttgtcaa ggggataactaccacaaaggggtaccttatgaaaccgactcagaggagagggaagcttat ttggaaatggactcacctgaaaggagatatatcccagatgaagctgactttctgttgggg atggccacagtgaacaactgtgtttcctatcgaagcactgtagagggatcctggtatatc cagtcactttgccagagtctgagagaaagatgtccccgaggcgatgatattctcaccatc ctgactgaagtaaactatgacgtgagcaataaggatgacaggatacacaaggggaaacaa atgccacaacccaccttcacactaagaaaaaaactctacttctctcttcactga

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