KEGG   Tupaia chinensis (Chinese tree shrew): 102500041
Entry
102500041         CDS       T02978                                 
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup01521  EGFR tyrosine kinase inhibitor resistance
tup04010  MAPK signaling pathway
tup04014  Ras signaling pathway
tup04015  Rap1 signaling pathway
tup04020  Calcium signaling pathway
tup04144  Endocytosis
tup04151  PI3K-Akt signaling pathway
tup04550  Signaling pathways regulating pluripotency of stem cells
tup04810  Regulation of actin cytoskeleton
tup05200  Pathways in cancer
tup05206  MicroRNAs in cancer
tup05219  Bladder cancer
tup05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:tup00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102500041 (FGFR3)
   04014 Ras signaling pathway
    102500041 (FGFR3)
   04015 Rap1 signaling pathway
    102500041 (FGFR3)
   04020 Calcium signaling pathway
    102500041 (FGFR3)
   04151 PI3K-Akt signaling pathway
    102500041 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102500041 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    102500041 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102500041 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102500041 (FGFR3)
   05206 MicroRNAs in cancer
    102500041 (FGFR3)
   05230 Central carbon metabolism in cancer
    102500041 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    102500041 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102500041 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tup01001]
    102500041 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:tup04090]
    102500041 (FGFR3)
Enzymes [BR:tup01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     102500041 (FGFR3)
Protein kinases [BR:tup01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   102500041 (FGFR3)
CD molecules [BR:tup04090]
 Proteins
  102500041 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set FGFR3_TM C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 102500041
NCBI-ProteinID: XP_014444984
LinkDB
Position
Un
AA seq 808 aa
MGARSCALALCVAVAVMARATSEPLGTELRVVRRAAEVPGPEPSQKEQLVFGSGDTLELS
CHLPGGGPMGPTVWVKDGAGLVPSDRILVGPQRLQVLNASHEDTGAYSCRQQLTQRVLCH
FSVRVTDAPSSGDDEDGEDEAEDTGAPYWTRPERMDKKLLAVPVPAANTVRFRCPAAGNP
TPSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIQQTYT
LDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDG
TPYVTVLKSWISENVEADARLRLANVSERDGGEYLCRATNFIGVAEKAFWLRVHGPQAVE
EDLVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKVSRFPLK
RQVTVSLESNSSMNSNTPLVRIARLSSGEGPTLANVSELELPADPKWELSRARLTLGKPL
GEGCFGQVVMAEAIGIDKERAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNI
INLLGACTQGGPLYVLVEYAAKGNLREYLRARRPPGMDYSFDTCKLPEEQLTFKDLVSCA
YQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPV
KWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPAN
CTHDLYMIMRECWHAVPSQRPTFKQLVEDLDRILTVTSTDEYLDLSVPFEQYSPGGQDTP
SSSSSGDDSVFTHDLLPPAPPSSGGPRT
NT seq 2427 nt   +upstreamnt  +downstreamnt
atgggcgcccggtcctgcgcccttgcgctctgcgtggccgtggcggtcatggcccgcgcc
acctcggagcccctgggcaccgagttgcgcgtggtgcgaagagcggcagaagtcccgggc
cctgaacccagccagaaggagcagttggtcttcggtagtggagacaccctggaactgagc
tgccacctgcctggaggtggtcccatggggcccaccgtctgggtcaaggatggcgcaggg
ctagtgccctcggaccgcatactggtggggccccagcggcttcaggtgttgaatgcctcc
cacgaggacactggggcctacagctgccggcagcagctcacccagcgtgtgctgtgccac
ttcagtgtgcgtgtaacggatgctccatcctcaggagatgatgaagatggggaggacgaa
gctgaagacacaggggccccttactggactcggcctgagcggatggacaagaagctgctg
gctgtgccagtcccagccgccaacacagttcgtttccgctgtccggctgctggcaacccc
actccctccatctcctggctgaagaatggcaaagagttccgtggggagcatcgcataggg
ggcatcaagctacggcaccagcagtggagcctggtcatggagagcgtggtgccctcggac
cgcggcaactacacctgtgtggtggagaacaagttcggcagcattcagcagacgtacacg
ctggacgtgctggagcgctctccgcaccggcccatcctgcaggcggggctgccggccaac
cagacggcagtgctgggcagcgacgtggagttccactgcaaggtgtacagtgacgcccag
ccccacatccagtggctcaagcatgtggaggtgaacggcagcaaggtgggccccgacggc
acgccctacgtcaccgtgctcaagtcctggatcagtgagaatgtggaggccgacgcacgc
ctccgcctggccaatgtgtcggagcgggatgggggcgagtacctctgtcgagccaccaat
ttcataggcgtggctgagaaggccttttggctgcgtgttcatgggccccaagcagttgag
gaggatctggtggaggctgacgaggctggcagtgtgtacgcaggcatcctcagctatggg
gtgggcttcttcctcttcatcctggtggtggcagccgtgacgctctgccgcctgcgcagc
ccccccaagaagggcctgggctcacccaccgtgcacaaggtctcccgtttcccgctcaag
cgacaggtaacagtatccttggagtccaattcgtcgatgaactccaacacgccactggtc
cgcattgcccggctgtcctccggagagggccccacgctggccaacgtctctgagcttgag
ctgcctgctgatcccaagtgggagctctcccgggcccggttgaccctaggcaagcctctc
ggggagggctgctttggccaggtggtcatggcagaggccattggcatcgacaaggagcgt
gctgctaagcccgtcactgtggctgtgaagatgctgaaagacgatgccaccgacaaggac
ctgtcagacctggtgtccgagatggagatgatgaagatgatcggcaagcacaagaacatc
atcaacctgctgggggcctgcacgcagggcgggcccctgtacgtgctggtggagtatgcg
gccaagggcaatctgagggagtacctgcgggcacggcggcctccgggcatggactactcc
ttcgacacctgcaaactgcctgaggagcagctcaccttcaaggacctggtgtcctgtgcc
taccaggtggcccggggcatggagtacctagcctcccagaagtgcatccacagggacctg
gctgcccgcaatgtgctggtgacagaggacaacgtgatgaagatcgcagatttcggcctt
gcccgcgacgtgcacaaccttgactactataagaagaccaccaatggccggctgcctgtg
aaatggatggcacccgaggccttgttcgaccgagtctatacccaccagagtgacgtttgg
tccttcggggtcctgctgtgggagatcttcacgctggggggttcaccatatcctggcatc
ccagtggaggagctctttaagctgctgaaggagggccaccgcatggataagccggccaac
tgcacacacgacctgtacatgatcatgcgggaatgctggcacgccgtaccgtcgcagcgg
cccaccttcaagcagctggtggaggatctggatcgcatcctcaccgtgacgtccacagat
gaatacctggacttgtcggtgccctttgagcagtactccccgggaggccaggacaccccc
agctccagctcctcgggggatgactccgtgtttacccatgacctgctgcctccggcccca
cccagcagcgggggcccaaggacatga

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